CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.970 | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.970 |
| Functional Family | 1-deoxy-D-xylulose-5-phosphate synthase |
Enzyme Information
| 2.2.1.7 |
1-deoxy-D-xylulose-5-phosphate synthase.
based on mapping to UniProt P77488
Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO(2).
-!- The enzyme forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis. -!- Formerly EC 4.1.3.37.
|
UniProtKB Entries (1)
| P77488 |
DXS_ECOLI
Escherichia coli K-12
1-deoxy-D-xylulose-5-phosphate synthase
|
PDB Structure
| PDB | 2O1S |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal Structure of 1-Deoxy-D-xylulose 5-Phosphate Synthase, a Crucial Enzyme for Isoprenoids Biosynthesis.
J.Biol.Chem.
|
