CATH Domain 2m0pA00

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CATH Classification

Level	CATH Code	Description
	4	Few Secondary Structures
	4.10	Irregular
	4.10.400	Low-density Lipoprotein Receptor
	4.10.400.10	Low-density Lipoprotein Receptor

Domain Context

CATH Clusters

Superfamily	Low-density Lipoprotein Receptor
Functional Family	LDL receptor related protein 2

Enzyme Information

UniProtKB Entries (1)

LRP2_HUMAN

Homo sapiens

Low-density lipoprotein receptor-related protein 2

PDB Structure

PDB	2M0P
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Gentamicin binds to the megalin receptor as a competitive inhibitor using the common ligand binding motif of complement type repeats: insight from the nmr structure of the 10th complement type repeat domain alone and in complex with gentamicin. Dagil, R., O'Shea, C., Nykjar, A., Bonvin, A.M., Kragelund, B.B. J.Biol.Chem.