CATH Domain 2hrtA07

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.1440	Multidrug efflux transporter AcrB pore domain

Domain Context

CATH Clusters

Superfamily	Multidrug efflux transporter AcrB pore domain
Functional Family	Multidrug efflux pump subunit AcrB

Enzyme Information

UniProtKB Entries (1)

ACRB_ECOLI

Escherichia coli K-12

Multidrug efflux pump subunit AcrB

PDB Structure

PDB	2HRT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Seeger, M.A., Schiefner, A., Eicher, T., Verrey, F., Diederichs, K., Pos, K.M. Science