CATH Domain 1z00B00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family	DNA repair endonuclease XPF isoform X2

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt Q92889

UniProtKB Entries (1)

ERCC1_HUMAN

Homo sapiens

DNA excision repair protein ERCC-1

PDB Structure

PDB	1Z00
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	The Structure of the Human ERCC1/XPF Interaction Domains Reveals a Complementary Role for the Two Proteins in Nucleotide Excision Repair Tripsianes, K., Folkers, G., Ab, E., Das, D., Odijk, H., Jaspers, N.G.J., Hoeijmakers, J.H.J., Kaptein, R., Boelens, R. Structure