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1 keywords

CATH Domain 1y11A02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.70 Alpha-Beta Plaits
Homologous Superfamily 3.30.70.1230 Nucleotide cyclase

Domain Context

CATH Clusters

Superfamily Nucleotide cyclase
Functional Family pH-sensitive adenylate cyclase Rv1264

Enzyme Information

4.6.1.1
Adenylate cyclase.
based on mapping to UniProt P9WMU9
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.

UniProtKB Entries (1)

P9WMU9
Y1264_MYCTU
Mycobacterium tuberculosis H37Rv
PH-sensitive adenylate cyclase Rv1264

PDB Structure

PDB 1Y11
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of a pH-sensing mycobacterial adenylyl cyclase holoenzyme
Tews, I., Findeisen, F., Sinning, I., Schultz, A., Schultz, J.E., Linder, J.U.
Science
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