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CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.30.50
Functional Family

Enzyme Information

4.2.1.84
Nitrile hydratase.
based on mapping to UniProt Q7SID3
An aliphatic amide = a nitrile + H(2)O.
-!- Acts on short-chain aliphatic nitriles, converting them into the corresponding acid amides. -!- Does not act on these amides or on aromatic nitriles (cf. EC 3.5.5.1).

UniProtKB Entries (1)

Q7SID3
NHAB_PSETH
Pseudonocardia thermophila
Cobalt-containing nitrile hydratase subunit beta

PDB Structure

PDB 1UGR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding
Miyanaga, A., Fushinobu, S., Ito, K., Shoun, H., Wakagi, T.
Eur.J.Biochem.
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