CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.950 |
Domain Context
CATH Clusters
| Superfamily | 1.10.10.950 |
| Functional Family | Protein Rep68 |
Enzyme Information
| 3.6.4.12 |
DNA helicase.
based on mapping to UniProt P03132
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
| P03132 |
REP68_AAV2S
Adeno-associated virus 2 Srivastava/1982
Protein Rep68
|
PDB Structure
| PDB | 1U0J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of adeno-associated virus type 2 Rep40-ADP complex: Insight into
nucleotide recognition and catalysis by superfamily 3 helicases
Proc.Natl.Acad.Sci.USA
|
