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1 keywords

CATH Domain 1o7qA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.90 Alpha-Beta Complex
Topology 3.90.550 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Homologous Superfamily 3.90.550.10 Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family Histo-blood group ABO system transferase

Enzyme Information

2.4.1.87
N-acetyllactosaminide 3-alpha-galactosyltransferase.
based on mapping to UniProt P14769
UDP-alpha-D-galactose + beta-D-galactosyl-(1->4)-beta-N-acetyl-D- glucosaminyl-R = UDP + alpha-D-galactosyl-(1->3)-beta-D-galactosyl- (1->4)-beta-N-acetylglucosaminyl-R.
-!- Acts on beta-galactosyl-1,4-N-acetylglucosaminyl termini on asialo- alpha(1)-acid glycoprotein and N-acetyllactosamine (beta-D- galactosyl-1,4-N-acetyl-beta-D-glucosamine), but not on 2'-fucosylated-N-acetyllactosamine. -!- The non-reducing terminal N-acetyllactosamine residues of glycoproteins can also act as acceptor. -!- Formerly EC 2.4.1.124 and EC 2.4.1.151.

UniProtKB Entries (1)

P14769
GGTA1_BOVIN
Bos taurus
N-acetyllactosaminide alpha-1,3-galactosyltransferase

PDB Structure

PDB 1O7Q
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity.
Zhang, Y., Swaminathan, G.J., Deshpande, A., Boix, E., Natesh, R., Xie, Z., Acharya, K.R., Brew, K.
Biochemistry
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