CATH Domain 1luaA01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.10280	Methylene-tetrahydromethanopterin dehydrogenase, N-terminal domain

Domain Context

CATH Clusters

Superfamily	Methylene-tetrahydromethanopterin dehydrogenase, N-terminal domain
Functional Family

Enzyme Information

1.5.1.5	Methylenetetrahydrofolate dehydrogenase (NADP(+)). based on mapping to UniProt P55818 5,10-methylenetetrahydrofolate + NADP(+) = 5,10- methenyltetrahydrofolate + NADPH.
1.5.1.-	With NAD(+) or NADP(+) as acceptor. based on mapping to UniProt P55818

UniProtKB Entries (1)

MTDA_METEA

Methylorubrum extorquens AM1

Bifunctional protein MdtA

PDB Structure

PDB	1LUA
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of methylene-tetrahydromethanopterin dehydrogenase from methylobacterium extorquens AM1. Ermler, U., Hagemeier, C.H., Roth, A., Demmer, U., Grabarse, W., Warkentin, E., Vorholt, J.A. Structure