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1 keywords

CATH Domain 1khcA01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.30 Roll
Topology 2.30.30 SH3 type barrels.
Homologous Superfamily 2.30.30.140  

Domain Context

CATH Clusters

Superfamily 2.30.30.140
Functional Family DNA (Cytosine-5)-methyltransferase 3B isoform 3

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt O88509
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

O88509
DNM3B_MOUSE
Mus musculus
DNA (cytosine-5)-methyltransferase 3B

PDB Structure

PDB 1KHC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds.
Qiu, C., Sawada, K., Zhang, X., Cheng, X.
Nat.Struct.Biol.
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