CATH Classification

Domain Context

CATH Clusters

Superfamily Peptidase S8/S53 domain
Functional Family Tripeptidyl peptidase 2

Enzyme Information

3.4.14.10
Tripeptidyl-peptidase II.
based on mapping to UniProt Q9V6K1
Release of an N-terminal tripeptide from a polypeptide.
-!- A cytosolic enzyme active at neutral pH. -!- Inhibited by diisopropyl fluorophosphate. -!- Belongs to peptidase family S8. -!- Formerly EC 3.4.14.8.

UniProtKB Entries (1)

Q9V6K1
TPP2_DROME
Drosophila melanogaster
Tripeptidyl-peptidase 2

PDB Structure

PDB 3LXU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Hybrid molecular structure of the giant protease tripeptidyl peptidase II.
Chuang, C.K., Rockel, B., Seyit, G., Walian, P.J., Schonegge, A.M., Peters, J., Zwart, P.H., Baumeister, W., Jap, B.K.
Nat.Struct.Mol.Biol.