CATH Classification

Domain Context

CATH Clusters

Superfamily Chorismate lyase-like
Functional Family Chorismate pyruvate-lyase

Enzyme Information

4.1.3.40
Chorismate lyase.
based on mapping to UniProt P26602
Chorismate = 4-hydroxybenzoate + pyruvate.
-!- Catalyzes the first step in the biosynthesis of ubiquinone in Escherichia coli and other Gram-negative bacteria. -!- The yeast Saccharomyces cerevisiae can synthesize ubiquinone from either chorismate or tyrosine.

UniProtKB Entries (1)

P26602
UBIC_ECOLI
Escherichia coli K-12
Chorismate pyruvate-lyase

PDB Structure

PDB 2AHC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural analysis of ligand binding and catalysis in chorismate lyase
Smith, N.N., Roitberg, A.E., Rivera, E., Howard, A., Holden, M.J., Mayhew, M., Kaistha, S., Gallagher, D.T.
Arch.Biochem.Biophys.