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1 keywords

CATH Domain 1m0eA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.150 Vaccinia Virus protein VP39

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P05102
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P05102
MTH1_HAEPH
Haemophilus parahaemolyticus
Modification methylase HhaI

PDB Structure

PDB 1M0E
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
ZEBULARINE: A NOVEL DNA METHYLATION INHIBITOR THAT FORMS A COVALENT COMPLEX WITH DNA METHYLTRANSFERASES
Zhou, L., Cheng, X., Connolly, B.A., Dickman, M.J., Hurd, P.J., Hornby, D.P.
J.MOL.BIOL.
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