CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10860 | Leucine Dehydrogenase, chain A, domain 1 |
Domain Context
CATH Clusters
| Superfamily | Leucine Dehydrogenase, chain A, domain 1 |
| Functional Family | Methylenetetrahydrofolate dehydrogenase [NAD(+)] |
Enzyme Information
| 1.5.1.15 |
Methylenetetrahydrofolate dehydrogenase (NAD(+)).
based on mapping to UniProt Q02046
5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.
|
UniProtKB Entries (1)
| Q02046 |
MTD1_YEAST
Saccharomyces cerevisiae S288C
Methylenetetrahydrofolate dehydrogenase [NAD(+)]
|
PDB Structure
| PDB | 1EE9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Protein Sci.
|
