CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Malate dehydrogenase 2, mitochondrial

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P40926
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P40926
MDHM_HUMAN
Homo sapiens
Malate dehydrogenase, mitochondrial

PDB Structure

PDB 2DFD
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Human Malate Dehydrogenase Type 2
Ugochukwu, E., Shafqat, N., Rojkova, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Oppermann, U.
To be Published