CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.20 | Single Sheet |
|
2.20.28 | Rubrerythrin, domain 2 |
|
2.20.28.20 | Methionyl-tRNA synthetase, Zn-domain |
Domain Context
CATH Clusters
| Superfamily | Methionyl-tRNA synthetase, Zn-domain |
| Functional Family | Methionine--tRNA ligase 1 |
Enzyme Information
| 6.1.1.10 |
Methionine--tRNA ligase.
based on mapping to UniProt P00959
ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met).
-!- In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9.
|
UniProtKB Entries (1)
| P00959 |
SYM_ECOLI
Escherichia coli K-12
Methionine--tRNA ligase
|
PDB Structure
| PDB | 1F4L |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
How methionyl-tRNA synthetase creates its amino acid recognition pocket upon L-methionine binding.
J.Mol.Biol.
|