The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Ribosomal protein S18

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ribosomal protein S18

This superfamily entry includes the ribosomal protein S18, found in the small subunit (30S) of the bacterial ribosome, as well as eubacterial S18, metazoan mitochondrial S18, algal and plant chloroplast S18 and cyanelle S18.

S18 is thought to be involved in binding of the aminoacyl-tRNA complex, due to its location within the platform (P) region. S18 is well exposed on the surface of the E. coli ribosome, and is a secondary rRNA binding protein. Along with other ribosomal proteins (S15 and S6), S18 contributes to the formation of the tree-helix junction in the central domain of 16S rRNA (three-helix junction). The S18 protein, unlike S15 and S6, contains a single small element of regular secondary structure, yet it forms a compact structure tightly packed against S6 and the RNA.

PFAM:PF01084, INTERPRO:IPR036870,PMID:11007480,DOI:10.1126/science.288.5463.107

GO Diversity

Unique GO annotations
23 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
21657 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 338
Domain clusters (>95% seq id): 6
Domain clusters (>35% seq id): 4
Unique PDBs: 336
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 44
Unique EC:
Unique GO: 23
Unique Species: 21657