The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
GPCR, family 2, extracellular hormone receptor domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
613
3D
4dlqA01 - 75.8
2
611
3D
4dloB01 - 84.8
3
373 - - 71.3
4
298 - - 71.2
5
187
3D
3l2jB02 - 80.0
6
169
3D
2jndA00 - 42.8
7
142
3D
3ehuB03 - 76.3
8
117 - - 74.6
9
109
3D
4lf3F00 - 87.7
11
105
3D
3n7sB00 - 74.5
12
99
3D
5ii0C00 - 71.6
13
98
3D
5e94H00 - 71.5
10
98 - - 46.1
14
89
3D
2xdgB01 - 86.0
15
86 - - 66.7
16
78 - - 91.4
17
61 - - 84.0
18
58 - - 86.2
19
47
3D
4hj0B00 - 63.7
20
43 - - 14.6
21
40 - - 93.9
22
pituitary
33 - - 75.1
23
33 - - 80.1
24
32 - - 72.9
25
22 - - 59.3
26
17 - - 54.8
27
16 - - 9.2
28
Cadherin plus 7TM domain
15 - - 17.6
29
13 - - 81.3
30
11 - - 46.4
31
10 - - 79.0
32
8 - - 40.0
36
7 - - 64.2
37
7 - - 82.7
33
7 - - 88.6
35
7 - - 10.4
34
7 - - 16.1
38
5 - - 52.5
39
4 - - 58.8
40
4 - - 6.5
41
3 - - 47.2
42
3 - - 5.6
61
2 - - 0.0
48
2 - - 18.7
55
2 - - 0.0
68
2 - - 24.3
60
2 - - 0.0
63
2 - - 0.0
43
2 - - 34.9
44
2 - - 34.0
62
2 - - 2.1
49
2 - - 21.5
50
2 - - 9.5
56
2 - - 0.0
58
2 - - 40.4
51
2 - - 0.0
57
2 - - 19.5
46
2 - - 39.3
64
2 - - 6.3
45
2 - - 36.2
52
2 - - 0.0
65
2 - - 2.1
53
2 - - 0.0
66
2 - - 0.0
59
2 - - 7.4
67
2 - - 0.0
47
2 - - 40.8
54
pituitary
2 - - 0.0
78
1 - - 0.0
89
1 - - 0.0
80
1 - - 0.0
82
1 - - 0.0
69
1 - - 0.0
90
1 - - 0.0
81
1 - - 0.0
76
1 - - 0.0
84
1 - - 0.0
77
1 - - 0.0
79
1 - - 0.0
83
Fragment
1 - - 0.0
70
1 - - 0.0
71
1 - - 0.0
85
1 - - 0.0
74
1 - - 0.0
86
1 - - 0.0
75
1 - - 0.0
87
1 - - 0.0
72
1 - - 0.0
73
1 - - 0.0
88
1 - - 0.0