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CATH Superfamily 3.90.850.10

Fumarylacetoacetase-like, C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Fumarylacetoacetase-like, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
2-oxo-hepta-3-ene-1,7-dioic acid hydratase
255
3D
 2eb6E00 - 71.6
2
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
237
3D
 2dfuD02 - 93.9
3
Fumarylacetoacetate hydrolase domain-containing 1
231
3D
 6fohB00 - 94.9
4
Fumarylacetoacetase
230
3D
 2hzyB02 - 80.5
5
FAA hydrolase family protein
113 - - 73.8
6
2-keto-4-pentenoate hydratase
104
3D
 2wqtT00 - 12.8
7
Fumarylacetoacetate hydrolase family protein
86
3D
 1nr9D00 - 83.0
8
FAA hydrolase family protein
63 - - 88.6
9
Fumarylacetoacetase
59 - - 79.0
10
FAA hydrolase family protein
51 - - 62.3
11
Fumarylacetoacetase
43 - - 83.9
12
Putative 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase
37 - - 70.0
13
4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase
28 - - 3.4
14
Uncharacterized mitochondrial hydrolase FMP41
26
3D
 1nkqF00 - 83.5
15
2-keto-4-pentenoate hydratase
15 - - 17.4
16
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase
Catechol pathway
15 - - 63.3
17
Acylpyruvase FAHD1, mitochondrial
14 - - 68.4
30
2-dehydro-3-deoxy-D-arabinonate dehydratase
13
3D
 3bqbZ02 - 0.0
18
Putative hydrolase
12 - - 6.4
20
Putative 4-hydroxyphenylacetate degradation bifunctional isomerase
10 - - 80.1
19
Fumarylacetoacetate hydrolase
10 - - 5.0
21
2-keto-4-pentenoate hydratase
9 - - 38.9
22
Hypothetical_protein_-_conserved
9 - - 13.5
23
Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase + cyclase/dehydrase
9 - - 8.0
24
2-keto-4-pentenoate hydratase
8 - - 13.6
26
2-keto-4-pentenoate hydratase
6 - - 17.3
25
5-oxo-1,2,5-tricarboxilic-3-penten aciddecarboxilase/isomer
6 - - 55.7
27
Fumarylacetoacetate_
FAA
5 - - 43.3
29
Fumarylacetoacetate hydrolase domain-containing protein 2A
4 - - 13.4
28
FAA hydrolase family protein
4 - - 9.5
32
Uncharacterized protein
3 - - 0.0
31
Putative hydratase
3 - - 1.4
39
2 - - 0.0
35
Uncharacterized protein
2 - - 0.0
36
2-hydroxyhexa-2,4-dienoate hydratase
2 - - 0.0
40
Mitochondrion protein, putative
2 - - 6.0
37
2 - - 9.2
41
2-hydroxypenta-2,4-dienoate hydratase
2 - - 0.0
43
2 - - 0.0
33
2 - - 0.6
38
Hydratase
2 - - 0.0
42
2 - - 0.0
34
2 - - 0.0
51
1 - - 0.0
48
1 - - 0.0
46
1 - - 0.0
45
1 - - 0.0
52
1 - - 0.0
53
1 - - 0.0
44
1 - - 0.0
49
1 - - 0.0
50
1 - - 0.0
47
1 - - 0.0