The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
FAD/NAD(P)-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
112468
30768
EC
3D
1kf6A01 - 94.2
112809
25266
EC
- - 64.3
112565
19708
EC
- - 96.8
113530
18512
EC
3D
3oz2A01 - 96.6
112452
17523
EC
3D
1fl2A02 - 92.9
113557
15224
EC
- - 94.2
112733
13823
EC
3D
1fl2A01 - 88.8
112787
13582
EC
3D
1gerA01 - 67.3
112229
Hg(II
12261
EC
3D
1zk7A01 - 79.9
113436
11730
EC
3D
1w4xA01 - 94.5
113158
9155
EC
3D
1d4cA02 - 91.6
112741
9080
EC
3D
1knpA01 - 95.0
113610
7988
EC
3D
1vrqB01 - 87.6
113044
7248
EC
- - 89.9
113441
7215
EC
3D
2rghA01 - 93.7
113138
6769
EC
- - 89.2
113575
5995
EC
3D
1cl0A01 - 90.2
112570
uracil-5-
5820
EC
3D
3g5qA01 - 93.8
113090
uracil-5-
5528
EC
- - 97.7
112567
4640
EC
- - 89.7
9767
P
4602 - - 15.5
113553
+
3975
EC
- - 88.1
78176
+
3945
EC
- - 40.4
112693
P
3838 - - 97.2
113784
3778
EC
- - 73.5
72451
3742
EC
- - 97.1
112736
3581 - - 80.4
113199
3488
EC
3D
3awiA02 - 93.8
10097
3267 - - 76.0
112473
3085
EC
3D
1ebdA01 - 39.8
112932
2935
EC
3D
3lzwA01 - 87.7
50216
2612
EC
- - 16.0
112069
2364
EC
- - 96.3
112903
2310
EC
3D
1rp0A02 - 94.6
112759
2244
EC
- - 73.5
111947
2191
EC
- - 73.3
112550
2123
EC
3D
4j2wA00 - 87.6
112259
3-
3-hydroxy-phenyl
2048
EC
- - 95.4
113911
1772
EC
- - 92.4
112819
1768
EC
- - 96.7
112456
1750
EC
3D
1lpfA01 - 72.4
64278
1616
EC
3D
1ps9A03 - 63.6
112428
1510
EC
3D
2cfyA01 - 82.1
113097
1336
EC
- - 86.2
113168
1308
EC
3D
2hqmA01 - 84.4
112785
1257
EC
- - 89.1
113558
1154
EC
3D
1lqtA02 - 91.9
113543
1123
EC
3D
2bc0A01 - 79.6
113066
1088
EC
3D
2e5vA01 - 91.5
113868
967
EC
3D
1fcdA01 - 92.4
113012
867
EC
3D
1ukvG01 - 84.9
113182
Nadph
817
EC
- - 90.7
4118
812
EC
3D
1zoyA01 - 88.2
111939
754
EC
3D
2q0kA02 - 54.5
111672
682
EC
3D
1e7pA01 - 80.6
9226
579
EC
- - 59.0
112293
579
EC
- - 79.6
114026
568
EC
3D
1fcdA02 - 98.9
112593
564
EC
- - 72.8
112735
L-lysine 6-monooxygenase Lysine N6-hydroxylase
559
EC
- - 88.0
112483
522
EC
- - 80.7
113075
507
EC
3D
5jciA01 - 86.7
112405
490
EC
- - 83.0
113474
489
EC
- - 91.0
112789
488
EC
- - 2.0
113721
NAD(P
479
EC
- - 85.3
1667
469
EC
- - 57.4
113130
uracil-5-
446
EC
- - 88.7
73879
399
EC
- - 3.8
113929
362
EC
- - 95.7
112986
357
EC
- - 83.5
113763
355
EC
- - 85.0
113021
310
EC
- - 74.0
78468
293
EC
3D
1zmcA02 - 75.6
113930
291
EC
3D
5jciA02 - 87.5
113449
284
EC
3D
2bxrA01 - 90.1
1243
274
EC
- - 5.9
111955
273
EC
- - 92.6
113272
262
EC
- - 92.6
113643
261
EC
- - 94.5
114154
AFU_orthologue AFUA_5G03540
228
EC
- - 96.0
112529
216
EC
3D
1zmcA01 - 79.0
113325
213
EC
- - 93.7
23882
P
211 - - 42.1
113851
205
EC
3D
5cqfA00 - 95.0
112990
1
204
EC
- - 78.6
19214
196 - - 0.0
113576
188
EC
- - 93.8
113007
186
EC
- - 93.3
113405
3-
3-hydroxy-phenyl
180
EC
- - 96.2
113996
179
EC
- - 67.3
113477
178 - - 74.6
113298
173 - - 91.7
59439
173
EC
- - 12.0
44846
NADPH
170
EC
3D
3s5wA00 - 55.1
48177
170
3D
1gv4A02 - 79.3
112444
169
EC
- - 55.1
112643
165
EC
3D
1dxlA01 - 70.5
113723
161
EC
- - 81.2
112355
154
EC
- - 49.6
85488
154
EC
3D
1bwcA02 - 82.9
113829
138
EC
- - 80.2
112073
134
EC
- - 58.4
113863
124
EC
- - 84.8
112505
124
EC
- - 67.6
112438
122
EC
3D
1lvlA01 - 36.9
112147
121
EC
3D
1cjcA02 - 68.0
91916
121 - - 0.0
113402
117
EC
3D
1aogA01 - 74.9
113809
117 - - 90.3
113635
116
EC
- - 75.2
113277
115
EC
3D
1gosA01 - 40.3
112858
110
EC
- - 93.1
55890
103
3D
1gv4A01 - 70.9
113128
102
EC
- - 80.1
19606
95 - - 73.1
112945
93 - - 55.1
112385
86
EC
- - 56.8
111571
75 - - 60.7
111999
73
EC
3D
4b63A00 - 61.1
112322
72 - - 60.9
84037
71 - - 43.9
114130
71
EC
- - 60.3
113050
68
EC
- - 84.5
112492
66 - - 91.6
71797
64
EC
- - 0.0
113501
62
EC
- - 79.9
64703
61
EC
- - 17.1
6375
59
EC
- - 73.2
113114
uracil-5-
59
EC
- - 75.9
112445
53
EC
- - 14.2
63506
51
EC
3D
1xdiA01 - 21.8
112348
48
EC
- - 38.8
113620
44
EC
- - 92.9
74171
43
EC
- - 13.7
112745
41
EC
- - 57.2
114114
40 - - 5.8
113427
39
EC
3D
1ng3A01 - 26.0
70358
36 - - 13.9
22655
36 - - 0.0
112968
36
EC
- - 71.9
113884
P
35
EC
- - 93.9
112431
34
EC
- - 28.1
113555
32
EC
- - 26.9
73213
P
29
EC
- - 15.7
113801
27
3D
4wctA01 - 60.3
104350
27
3D
1b37A01 - 2.0
67474
25
EC
- - 5.5
39655
25
EC
- - 0.0
12145
20
EC
- - 20.3
112960
20 - - 48.7
113483
19 - - 92.3
112573
19 - - 86.9
112878
19
EC
3D
3ab1A01 - 51.9
68574
18
EC
3D
2nvkX01 - 23.2
112738
18
EC
- - 21.8
113383
17 - - 60.8
55108
17 - - 40.4
113482
16 - - 49.9
112678
16 - - 22.5
112816
16
EC
- - 0.0
113964
16 - - 0.0
113429
16
EC
- - 60.3
112763
15
EC
- - 72.4
112889
15
EC
- - 65.3
60322
14 - - 38.6
113649
14 - - 78.5
40215
12
EC
- - 12.3
113040
11
EC
- - 43.7
35207
11
EC
- - 11.0
112527
11
EC
- - 32.9
112314
10 - - 0.0
78132
+
10 - - 20.2
112822
10
3D
4jdrA01 - 21.2
112908
Nfrl
10 - - 25.1
87383
+
10 - - 17.9
50444
10 - - 4.0
17452
9
EC
- - 51.5
113580
P
9
EC
- - 36.9
30061
9 - - 0.0
113262
9 - - 0.0
113735
9
EC
- - 79.4
113626
9 - - 64.4
113091
+
8
EC
- - 50.5
113960
8
EC
- - 39.6
58041
8
EC
- - 11.3
113146
7 - - 54.6
113886
uracil-5-
7
EC
- - 66.2
113119
7
EC
- - 57.8
57852
7
EC
- - 16.5
16926
6 - - 27.1
14434
6 - - 5.7
103321
6 - - 18.8
58833
6
EC
- - 8.1
113018
5
EC
- - 0.7
113713
5 - - 4.3
84686
5
EC
- - 9.6
112067
5 - - 16.8
113946
4 - - 0.0
113286
4
EC
- - 31.9
19583
4
EC
- - 0.0
66518
4
EC
- - 6.9
15506
4
EC
- - 0.0
49710
4
EC
- - 22.8
33940
4 - - 0.0
73385
4
EC
- - 3.7
56386
4 - - 0.0
113687
4
EC
- - 0.0
35500
4 - - 0.0
92381
3 - - 23.8
66919
3
EC
- - 0.5
113058
3 - -
112705
+
3
3D
3ef6A01 - 0.0
82972
3 - - 25.9
31732
3 - - 22.8
50942
3 - - 0.7
113268
2
EC
- - 39.8
111648
2
EC
- - 9.7
67334
2
EC
- - 0.0
113779
uracil-5-
2
EC
- - 37.3
107784
ANG_orthologue An01g14740
2 - - 0.0
50886
2
EC
- - 21.2
113847
2 - - 17.4
67614
2 - - 13.2
82579
+
2 - - 0.0
6443
2
EC
- - 0.4
143
2
EC
- - 0.0
6148
2 - - 14.1
63509
2
EC
- - 0.0
29404
2 - - 4.6
18618
2
EC
- - 15.8
113101
2 - - 14.2
113105
2 - - 15.2
105787
2
3D
1gpeA01 - 0.0
113430
Hg(II
2
EC
- - 18.1
23114
2 - - 4.5
113612
2 - - 0.0
65800
2
EC
- - 1.7
113546
uracil-5-
2
EC
- - 19.6
70692
2
EC
- - 9.1
112440
2 - - 0.0
113480
2
EC
- - 39.9
83883
+
2 - - 2.6
83025
1
EC
- - 0.0
63396
1
EC
- - 0.0
15733
1
EC
- - 0.0
113683
1
EC
- - 0.0
68016
1
EC
- - 0.0
95736
1 - -
77624
1
EC
- - 0.0
36866
1
EC
- - 0.0
90246
1
EC
- - 0.0
112064
1
EC
- - 0.0
16484
1
EC
- - 0.0
79695
1 - - 0.0
5481
1 - - 0.0
113329
1 - - 0.0
112731
1 - - 0.0
37002
1 - - 0.0
104920
1 - - 0.0
113707
1 - - 0.0
36097
1 - - 0.0
113442
1 - - 0.0
113715
1 - - 0.0
91012
1
EC
- - 0.0
82118
+
1
EC
- - 0.0
105862
1 - - 0.0
91948
1 - - 0.0
113389
1 - -
112554
1
EC
- - 0.0
112441
1 - -
92726
1
EC
- - 0.0
54915
1 - - 0.0
16144
1 - - 0.0
100427
1 - - 0.0
113034
P
1 - - 0.0
113997
AFU_orthologue AFUA_7G00150
1 - - 0.0