The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Alkaline Phosphatase, subunit A
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
613
3D
4qaxA01 - 94.0
2
397 - - 63.8
3
385 - - 71.1
4
306
3D
1p49A01 - 87.8
5
305
3D
4lrfC01 - 79.4
6
259
3D
5liaA03 - 76.7
8
221
3D
3mk2A00 - 94.6
7
211
3D
1fsuA01 - 70.0
10
182
3D
4gtzB01 - 83.2
9
181 - - 22.4
11
161 - - 81.9
40
136
3D
5c66B00 - 38.7
13
135
3D
3nvlB01 - 79.6
12
132 - - 77.0
15
124 - - 88.3
14
124 - - 18.4
17
123 - - 95.6
16
123 - - 43.2
18
114 - - 74.5
21
N-acetyl
113
3D
4fdjB01 - 76.1
19
112 - - 29.1
20
111 - - 42.0
23
104
3D
1n2lA01 - 87.2
22
101
3D
5fgnA02 - 86.0
26
97
3D
4mivH01 - 80.6
24
89 - - 19.0
25
88 - - 67.8
27
82 - - 90.2
29
79
3D
5eghB01 - 74.1
28
79 - - 81.9
31
65 - - 73.6
30
65 - - 17.7
32
63 - - 88.2
35
Putative
63
3D
4lr2A01 - 70.7
33
62 - - 83.8
34
60 - - 83.5
37
54 - - 86.2
36
54 - - 82.1
44
47
3D
5aj9B01 - 75.4
38
46 - - 63.4
39
45 - - 77.2
41
41 - - 83.7
43
39 - - 71.4
42
39 - - 30.1
45
32 - - 75.5
48
32
3D
5udyA01 - 86.2
47
31 - - 89.4
46
31 - - 10.4
49
29 - - 44.8
50
29 - - 79.4
51
28 - - 77.8
52
28 - - 80.5
53
24 - - 35.9
54
24 - - 49.7
62
21
3D
4uplC01 - 76.8
55
21 - - 1.2
57
20 - - 4.1
56
20 - - 73.0
58
AFU_orthologue AFUA_6G04290
19 - - 55.7
61
19 - - 94.0
60
19 - - 53.2
59
19 - - 12.4
63
18 - - 70.9
64
17 - - 82.3
65
16 - - 89.4
67
15 - - 72.3
66
15 - - 41.9
69
14 - - 7.6
68
14 - - 37.5
70
14 - - 88.4
71
13 - - 5.8
72
13 - - 3.7
73
13 - - 20.8
76
12 - - 78.4
74
12 - - 75.1
75
12 - - 10.4
77
11 - - 7.5
78
11 - - 63.2
79
11 - - 35.9
80
GALNS
11 - - 85.1
84
10 - - 12.6
82
10 - - 84.4
85
10 - - 12.8
83
10 - - 0.4
81
10 - - 40.0
92
10
3D
5tooA01 - 49.7
113
9
3D
1ei6D01 - 12.2
87
9 - - 82.3
86
9 - - 14.8
88
9 - - 80.9
90
8 - - 8.8
89
8 - - 0.0
93
8 - - 20.6
91
8 - - 75.1
101
7 - - 70.4
96
7 - - 34.7
98
7 - - 81.2
100
7 - - 11.6
94
7 - - 30.8
99
7 - - 73.1
102
7 - - 16.0
97
7 - - 75.4
95
7 - - 42.8
141
7
3D
5xwkA01 - 11.6
107
6 - - 27.3
109
6 - - 83.0
110
6 - - 47.4
112
6 - - 82.6
108
6 - - 78.4
104
6 - - 34.4
103
6 - - 38.0
106
6 - - 46.1
105
6 - - 68.7
111
6 - - 83.4
118
5 - - 9.0
119
5 - - 13.5
116
5 - - 43.7
120
5 - - 11.2
114
5 - - 19.5
115
5 - - 71.9
122
5 - - 56.8
121
5 - - 47.3
117
5 - - 85.2
123
5 - - 72.9
127
GALNS
4 - - 7.2
139
N-acetyl
4 - - 10.1
129
4 - - 27.0
135
4 - - 10.4
124
4 - - 35.5
136
4 - - 1.2
138
4 - - 0.0
137
4 - - 16.5
262
4
3D
4upkC01 - 0.0
126
4 - - 43.5
142
4 - - 67.5
128
4 - - 6.8
130
4 - - 15.2
140
4 - - 58.9
131
4 - - 27.7
143
4 - - 48.2
132
4 - - 36.6
125
4 - - 59.8
133
4 - - 39.7
134
4 - - 14.2
153
3 - - 7.5
168
3 - - 34.2
145
3 - - 35.8
160
3 - - 11.9
152
3 - - 1.4
144
3 - - 46.1
161
3 - - 1.2
151
3 - - 58.4
170
3 - - 37.2
167
3 - - 33.0
150
sulfamidase
3 - - 24.5
155
3 - - 10.2
163
3 - - 65.2
154
3 - - 5.5
159
3 - - 7.6
162
3 - - 37.4
158
3 - - 10.1
169
3 - - 57.2
148
3 - - 29.1
157
3 - - 8.9
165
3 - - 8.3
147
3 - - 11.9
149
3 - - 23.0
166
3 - - 4.7
156
3 - - 1.2
146
GALNS
3 - - 5.8
164
3 - - 11.8
206
2 - - 2.6
194
2 - - 33.2
220
2 - - 4.5
226
2 - - 20.3
211
2 - - 1.2
236
2 - - 21.9
218
GALNS
2 - - 9.7
178
GALNS
2 - - 4.2
234
2 - - 37.6
193
2 - - 31.0
180
2 - - 2.3
189
2 - - 24.7
221
2 - - 1.5
177
2 - - 6.3
205
2 - - 0.0
235
2 - - 40.2
213
2 - - 5.0
171
2 - - 4.4
200
2 - - 5.6
197
2 - - 11.0
191
2 - - 30.6
224
2 - - 33.7
187
2 - - 21.6
212
2 - - 5.2
176
2 - - 45.8
227
2 - - 0.0
182
2 - - 0.0
232
2 - - 32.5
225
2 - - 27.3
207
2 - - 3.2
192
2 - - 29.8
215
2 - - 7.0
233
2 - - 37.8
175
2 - - 31.2
208
2 - - 7.0
199
2 - - 5.7
198
2 - - 10.1
202
GALNS
2 - - 7.0
184
2 - - 2.4
181
2 - - 0.0
195
2 - - 36.1
230
A or B
2 - - 33.9
201
2 - - 0.0
174
2 - - 33.7
214
2 - - 6.5
229
Hunter syndrome
2 - - 22.9
188
2 - - 18.3
222
2 - - 0.0
217
2 - - 5.2
183
2 - - 0.0
190
2 - - 10.7
231
2 - - 34.7
203
GALNS
2 - - 7.7
204
2 - - 10.2
186
2 - - 4.1
228
2 - - 0.8
172
2 - - 17.4
223
2 - - 8.2
209
2 - - 0.0
216
2 - - 0.0
179
2 - - 0.0
210
2 - - 1.1
173
2 - - 22.6
219
2 - - 5.3
185
Partial
2 - - 1.0
196
2 - - 38.0
358
1 - - 0.0
331
1 - - 0.0
325
1 - - 0.0
378
1 - - 0.0
350
1 - - 0.0
337
1 - - 0.0
382
1 - - 0.0
340
1 - - 0.0
311
1 - - 0.0
348
1 - - 0.0
285
1 - - 0.0
364
1 - - 0.0
367
1 - - 0.0
288
1 - - 0.0
324
1 - - 0.0
244
1 - - 0.0
351
1 - - 0.0
246
1 - - 0.0
379
1 - - 0.0
342
1 - - 0.0
295
1 - - 0.0
341
1 - - 0.0
312
1 - - 0.0
260
1 - - 0.0
237
1 - - 0.0
370
1 - - 0.0
309
1 - - 0.0
380
1 - - 0.0
300
1 - - 0.0
286
1 - - 0.0
381
1 - - 0.0
308
1 - - 0.0
254
1 - - 0.0
373
1 - - 0.0
301
1 - - 0.0
296
1 - - 0.0
265
1 - - 0.0
366
1 - - 0.0
329
1 - - 0.0
272
1 - - 0.0
287
1 - - 0.0
294
1 - - 0.0
349
1 - - 0.0
275
1 - - 0.0
346
1 - - 0.0
333
1 - - 0.0
323
1 - - 0.0
352
1 - - 0.0
251
1 - - 0.0
369
1 - - 0.0
279
1 - - 0.0
256
1 - - 0.0
372
1 - - 0.0
264
1 - - 0.0
255
1 - - 0.0
359
1 - - 0.0
330
1 - - 0.0
263
1 - - 0.0
360
1 - - 0.0
293
1 - - 0.0
274
1 - - 0.0
322
1 - - 0.0
353
1 - - 0.0
375
1 - - 0.0
310
1 - - 0.0
250
1 - - 0.0
303
1 - - 0.0
278
1 - - 0.0
245
1 - - 0.0
267
1 - - 0.0
354
1 - - 0.0
257
1 - - 0.0
332
1 - - 0.0
276
1 - - 0.0
259
1 - - 0.0
368
1 - - 0.0
316
1 - - 0.0
347
1 - - 0.0
292
1 - - 0.0
291
1 - - 0.0
374
1 - - 0.0
241
1 - - 0.0
327
1 - - 0.0
320
1 - - 0.0
280
1 - - 0.0
273
1 - - 0.0
249
1 - - 0.0
361
1 - - 0.0
314
1 - - 0.0
307
1 - - 0.0
355
1 - - 0.0
326
1 - - 0.0
335
1 - - 0.0
270
1 - - 0.0
240
1 - - 0.0
334
1 - - 0.0
299
1 - - 0.0
377
1 - - 0.0
266
1 - - 0.0
302
1 - - 0.0
315
1 - - 0.0
338
1 - - 0.0
305
1 - - 0.0
328
1 - - 0.0
239
1 - - 0.0
281
1 - - 0.0
269
1 - - 0.0
363
1 - - 0.0
362
1 - - 0.0
317
1 - - 0.0
376
1 - - 0.0
298
1 - - 0.0
313
1 - - 0.0
243
1 - - 0.0
343
1 - - 0.0
261
1 - - 0.0
321
1 - - 0.0
284
1 - - 0.0
247
1 - - 0.0
371
1 - - 0.0
289
1 - - 0.0
339
1 - - 0.0
268
1 - - 0.0
345
1 - - 0.0
319
1 - - 0.0
282
1 - - 0.0
344
1 - - 0.0
238
1 - - 0.0
253
1 - - 0.0
357
1 - - 0.0
336
1 - - 0.0
297
1 - - 0.0
277
1 - - 0.0
290
1 - - 0.0
304
1 - - 0.0
258
1 - - 0.0
365
1 - - 0.0
306
1 - - 0.0
252
1 - - 0.0
283
1 - - 0.0
271
1 - - 0.0
318
1 - - 0.0
248
1 - - 0.0
356
1 - - 0.0
242
1 - - 0.0