The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
DD-peptidase/beta-lactamase superfamily
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
22200
Penicillin-binding protein 2
75977
EC
3D
3lo7A02 - 91.0
22165
D-alanyl-D-alanine carboxypeptidase
45152
EC
3D
1hd8A01 - 92.5
22203
13571
EC
3D
3fwlA02 - 89.3
22219
12035
EC
3D
4dxbA03 - 89.1
22194
Penicillin-binding protein Penicillinase
11077
EC
3D
1cefA00 - 94.6
22236
10740
EC
3D
4bqmA00 - 90.0
22220
8241
EC
- - 87.2
18018
6782
EC
- - 60.7
22208
4295
EC
3D
1c3bA00 - 97.6
17260
2160
EC
3D
1alqA00 - 80.8
21012
Beta-lactamase
1723
EC
3D
1m6kA00 - 48.0
22065
1702
EC
3D
1e3uA00 - 56.0
21978
1435
EC
3D
1k38A00 - 38.5
21251
1021
EC
3D
1xa1A00 - 22.9
15809
827
EC
- - 36.7
22209
752
EC
- - 69.7
10577
558
EC
- - 42.2
21735
444
3D
2iwbA00 - 3.2
22133
214
EC
- - 40.7
17694
213
EC
3D
1e25A00 - 29.3
16399
209
3D
3i7jA00 - 36.7
22210
185
EC
- - 85.0
8523
155 - - 16.1
10441
146
EC
- - 0.4
18138
134
EC
- - 3.7
7179
79
EC
- - 9.7
18583
75
EC
- - 9.2
5420
55 - - 4.3
22233
54
EC
3D
2wuqA00 - 86.9
10856
53
EC
3D
4gdnA00 - 2.2
15507
42
EC
- - 8.3
21736
39
EC
- - 14.6
20840
28
EC
- - 4.8
9731
21 - - 3.2
4277
21
EC
- - 22.6
19871
16
EC
- - 9.3
4880
14
3D
1qmeA02 - 20.2
9542
13
EC
- - 13.8
2485
5 - - 1.3
11699
5 - - 5.9
20325
5
EC
- - 2.6
10442
5 - - 0.0
9236
2 - - 12.9
21315
2 - - 8.6
781
AFU_orthologue AFUA_5G07500
2 - - 2.7