The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
115309
53144
EC
3D
4fleA00 - 88.4
115534
32478
EC
3D
3hjuA00 - 92.9
115121
32083
EC
3D
1mx1A00 - 90.5
115552
20873
EC
3D
2wudA00 - 96.5
115346
Oligopeptidase B
11180
EC
3D
3dduA01 - 94.5
115070
10306
EC
3D
1ivyA00 - 80.4
114106
9679 - - 43.8
115372
9295
EC
3D
2zshA00 - 87.1
115468
8893
EC
3D
2b61A01 - 91.8
114893
8273
EC
3D
3fcxA00 - 91.8
115030
7373
EC
3D
1u2eA00 - 95.7
115381
6043
EC
3D
1z68A02 - 88.7
115488
5884
EC
3D
2oxeA01 - 88.5
115693
5667
EC
3D
4xjvA00 - 90.8
83855
5625
EC
- - 2.9
115645
5561
EC
3D
1fj2A00 - 85.1
115799
5348
EC
3D
4qlaA00 - 84.3
115703
5096
EC
3D
5hk8A00 - 83.5
115089
5045
EC
3D
4gdmA00 - 92.8
115060
4980
EC
3D
1azwA00 - 94.2
115343
4842
EC
3D
1m33A00 - 90.3
115570
4458
3D
4krxA00 - 92.7
55772
4449
3D
3bf7A00 - 17.0
115324
4365
EC
3D
1hlgA00 - 79.7
115427
4133
EC
3D
3f67A00 - 97.9
115027
3951
3D
3v48A00 - 98.2
115041
Chloride peroxidase
3835
EC
3D
1a7uA00 - 95.0
115077
3523
EC
- - 95.0
114979
2784 - - 68.8
115363
2688
EC
- - 89.8
115356
1-chlorohexane halidohydrolase
2332
EC
3D
2o2hA00 - 95.3
115289
2282
EC
3D
1s8oA03 - 90.3
115351
2169
EC
3D
1f0nA00 - 91.8
115660
2123
EC
- - 82.5
38441
2079
EC
- - 85.9
60057
2069 - - 28.6
50791
1743
EC
- - 48.9
115731
1690
EC
3D
3wl5A00 - 83.8
115131
1477
EC
3D
3c5vA00 - 78.5
115085
1471
EC
3D
1lnsA02 - 95.1
115265
1314
EC
3D
1f6wA00 - 84.0
115538
1287
EC
- - 93.4
115185
1272
EC
- - 95.9
114056
3-hydroxyalkanoate
1149
EC
- - 45.6
115352
1098
3D
2qmqA00 - 83.1
115398
S09 family
955
EC
- - 91.3
115592
937
EC
- - 64.6
115401
935
EC
3D
3dcnA00 - 89.1
115655
Ferric enterobactin esterase
922
EC
3D
3mgaA02 - 96.7
114852
913
EC
- - 93.2
115241
848 - - 91.8
114886
815
EC
3D
2hihA00 - 92.9
114957
789 - - 91.0
115767
782
EC
- - 82.7
114870
756
EC
3D
3k2iA02 - 91.5
115235
693
EC
3D
1ex9A00 - 93.0
114701
639
EC
- - 83.5
115466
611
EC
- - 86.8
115281
607
EC
3D
3groA00 - 87.7
115511
Eurofung
603
EC
- - 89.1
115673
588
EC
- - 85.8
115195
547
EC
- - 92.6
115013
546
EC
3D
3d59A00 - 84.3
115567
542
EC
- - 82.6
114777
498
EC
- - 88.8
87976
488
EC
- - 95.3
115758
457
3D
2qs9A00 - 85.8
115213
452
EC
- - 93.1
115140
440 - - 79.0
115014
410
EC
3D
4xwgA01 - 86.7
47893
Non-haem peroxidase
390
EC
3D
3e3aA00 - 53.2
115474
388
EC
3D
1uswA00 - 97.7
115306
382
EC
3D
1pjaA00 - 86.0
115017
370
EC
- - 79.7
114146
369 - - 33.0
115164
357
EC
3D
3jyhA01 - 92.3
115558
344
EC
- - 95.6
115635
338
EC
3D
1ju3A01 - 94.7
22296
334
EC
3D
3p2mA00 - 68.6
115004
328 - - 89.8
114947
Human
326 - - 89.1
3206
292
EC
- - 83.5
114092
290 - - 83.3
71510
289 - - 0.0
97612
289 - - 0.0
114995
272 - - 84.7
93017
268
EC
- - 8.8
92715
258
EC
- - 2.8
115340
254
EC
- - 83.2
115807
253 - - 86.3
115790
252
EC
- - 93.0
115288
252
EC
- - 70.7
115420
246
EC
3D
1vlqA00 - 90.3
114349
237 - - 39.3
70145
235
3D
1ycdA00 - 11.3
22626
225
EC
- - 0.0
17674
225 - - 0.0
115757
223
EC
- - 76.9
114950
214
EC
3D
1i6wA00 - 40.6
114207
207
EC
3D
1tqhA00 - 33.6
115713
202
EC
- - 89.7
330
195
EC
3D
1dx4A00 - 87.3
114828
193
EC
- - 94.3
115364
190
EC
3D
1xktA01 - 83.4
115513
186
EC
3D
1ggvA00 - 92.8
93023
185
EC
- - 0.0
30379
181
EC
- - 4.9
33825
Non-haem peroxidase
180
EC
- - 4.6
115368
177
EC
- - 85.4
115636
175 - - 93.9
84338
170 - - 0.5
19558
170
EC
- - 0.7
75304
169
EC
- - 0.0
115627
167
EC
- - 87.6
114884
163
EC
- - 90.9
114738
163 - - 88.5
115496
AFU_orthologue AFUA_6G10800
159 - - 92.0
115456
158
EC
3D
2quaA01 - 87.0
17023
157
EC
- - 4.2
22610
146
EC
3D
1pv1A00 - 28.2
98872
146 - - 13.2
91596
142
EC
- - 2.4
115503
141
EC
- - 84.7
115207
137
EC
- - 89.6
22078
135
EC
- - 65.3
55835
134
EC
- - 0.0
115033
129
EC
- - 85.6
26620
126 - - 80.1
114355
125
EC
- - 75.4
114713
123
EC
- - 78.8
115581
121 - - 82.6
115455
120 - - 89.3
65195
115
EC
3D
3rliA00 - 19.3
99890
111 - - 11.3
114130
106 - - 74.1
114517
105
3D
1thtA00 - 69.3
69464
104
EC
- - 74.2
114123
104
EC
- - 69.5
115480
103
EC
3D
1jmkC01 - 76.1
90053
103 - - 65.5
56806
103 - - 78.7
57786
102 - - 0.0
40071
101 - - 25.5
114476
96
3D
1imjA00 - 86.6
12143
96 - - 27.2
13239
94 - - 1.0
115310
94
EC
- - 78.9
36914
93
EC
- - 7.8
114125
92 - - 86.4
50792
91 - - 67.9
29245
91
EC
- - 3.1
115192
90 - - 89.5
32781
87 - - 1.3
114644
85
EC
3D
2r11A00 - 66.9
114641
85 - - 65.9
15769
84 - - 24.6
114642
83
EC
- - 66.4
39769
83
EC
- - 1.9
115862
82 - - 63.6
91790
82 - - 0.9
46934
78 - - 87.6
114240
77 - - 34.9
115750
77 - - 93.8
115740
74 - - 91.7
15834
74 - - 6.9
56085
73
EC
- - 11.2
49973
73
EC
- - 10.8
115167
68 - - 66.3
11762
68
EC
- - 0.9
115727
68 - - 2.8
115598
67
EC
- - 59.7
114689
66
EC
- - 58.7
115096
D-
-
65
EC
- - 95.9
25374
65
EC
- - 0.4
59387
64
EC
- - 0.0
115791
63
EC
3D
1vkhA00 - 79.3
91795
62 - - 3.1
115063
62 - - 79.9
114675
61 - - 61.1
115227
59
EC
- - 85.2
25298
58
EC
- - 5.8
114956
58 - - 61.2
42448
57
EC
- - 8.5
32998
55
EC
- - 2.0
75292
54 - - 64.5
115361
Thymus
53 - - 60.7
90920
53 - - 16.5
63108
51 - - 7.1
114044
51
3D
2ocgA00 - 41.2
19157
51 - - 35.0
115624
50 - - 62.2
46933
49
EC
- - 20.7
115129
47
EC
- - 74.9
26243
44
EC
- - 23.0
71517
42
EC
- - 4.2
80906
41 - - 47.7
115471
39 - - 62.7
64745
38 - - 24.4
62542
38
EC
- - 3.6
115472
AFU_orthologue AFUA_7G01710
37
EC
- - 73.4
67761
36 - - 0.0
46936
36 - - 0.0
76544
36 - - 0.0
85080
34 - - 37.1
13008
33
EC
3D
1lbsA00 - 6.6
115768
32 - - 88.6
29458
32
EC
- - 7.1
105248
31
EC
- - 13.1
99
31
EC
- - 51.0
91689
30 - - 5.8
49252
30
EC
- - 7.8
53707
29 - - 3.1
49768
29
EC
- - 5.9
65192
29
EC
- - 31.5
95370
27 - - 3.7
58736
26 - - 1.4
29685
26 - - 42.7
53710
26 - - 1.3
69367
26
EC
- - 2.5
115087
26 - - 71.3
67760
26
EC
- - 16.7
115321
25
EC
3D
2wj3A01 - 41.7
75291
25 - - 0.0
32792
25 - - 0.0
106505
24 - - 50.0
115418
23
EC
- - 82.0
115760
23
EC
- - 87.9
115676
AFU_orthologue; AFUA_3G09230
22
EC
- - 86.1
98605
21 - - 39.0
30515
20
EC
- - 9.2
49559
20
EC
3D
1lgyA00 - 0.8
102372
18
EC
- - 9.5
16453
18 - - 67.1
24899
18
EC
3D
1j1iA00 - 4.9
115250
18
EC
- - 29.9
77290
18 - - 24.2
115450
18 - - 45.0
85490
18 - - 70.4
13629
17 - - 0.4
115109
17
EC
- - 72.2
49935
17 - - 9.6
97705
16 - - 0.0
78266
16 - - 0.0
115435
16 - - 51.4
95585
V
2
16
EC
- - 25.7
72590
16 - - 0.0
57784
15
EC
- - 13.9
75003
15 - - 23.0
114854
14
EC
3D
1bs9A00 - 22.3
2113
14 - - 29.8
115404
14 - - 55.4
78832
13 - - 0.5
115371
13 - - 51.3
115780
13 - - 44.0
52816
13 - - 16.4
16967
12 - - 3.5
78507
12 - - 16.3
44085
12 - - 13.6
77731
11
EC
3D
4e11A00 - 7.9
115157
AFU_orthologue AFUA_6G12740
11 - - 38.2
32716
11 - - 5.1
114825
10 - - 45.4
86174
10 - - 21.2
20563
10 - - 11.4
17551
10 - - 27.8
51529
10 - - 6.8
115169
10 - - 35.2
114087
10 - - 27.5
93375
9 - - 39.3
115522
9 - - 81.6
115430
AFU_orthologue; AFUA_5G13710
9 - - 15.8
115187
9
EC
- - 37.2
622
8
EC
- - 27.5
30068
8 - - 2.9
115278
8
EC
- - 36.5
26882
8 - - 1.1
114813
7 - - 37.0
115327
7 - - 63.6
3593
7 - - 3.7
21430
7 - - 14.7
9004
6 - - 12.6
40833
6 - - 12.2
43163
6
EC
- - 9.1
115632
6
EC
- - 53.8
39838
6 - - 17.9
65228
6 - - 6.5
114115
5 - - 30.0
35979
5
EC
- - 11.5
5967
5 - - 6.2
287
5
EC
- - 6.0
99097
5
EC
- - 5.1
7264
5 - - 0.7
65167
5 - - 4.6
92716
5
EC
- - 12.7
22181
5 - - 13.3
115563
5 - - 38.1
39253
5 - - 19.8
113989
5 - - 14.4
16780
4 - - 0.0
79819
4
EC
- - 0.0
62633
4
EC
- - 0.0
105814
4 - - 0.0
115826
4
EC
- - 41.4
32788
4 - - 0.0
74699
4 - - 0.0
76547
4 - - 0.0
57779
4
EC
- - 0.0
64960
3 - - 15.3
41488
3 - - 10.1
98608
3 - - 2.8
90571
3 - - 17.2
115410
3 - - 45.7
114832
3 - - 30.3
57765
3 - - 12.8
18869
3 - - 6.9
69918
3 - - 2.7
40684
3 - - 5.4
43509
3
EC
- - 3.7
115849
3
EC
- - 34.9
115009
3 - - 46.0
38644
2
EC
- - 4.8
23845
2 - - 8.2
84644
2 - - 0.0
73405
2 - - 5.6
110099
2
EC
- - 3.9
106218
2 - - 9.4
105919
2 - - 5.4
86707
2 - - 9.3
115150
2 - - 30.7
34495
AFU_orthologue AFUA_2G12490
2 - - 0.4
69371
2
EC
- - 0.0
35737
3-hydroxybutyrate
2
EC
- - 10.4
103733
2 - - 4.1
78828
2
EC
- - 6.3
115022
JCVI
2 - - 30.7
31364
2 - - 0.0
28410
2
EC
- - 0.8
51530
2
EC
- - 8.7
105673
2
EC
- - 0.0
45120
2 - - 9.0
91835
2 - - 5.7
30439
2
EC
- - 4.2
64330
1 - - 0.0
113303
1 - - 0.0
107207
1 - - 0.0
75347
1 - - 0.0
74696
1 - - 0.0
89295
1 - - 0.0
64332
1
EC
- - 0.0
82963
1 - - 0.0
78782
AFU_orthologue AFUA_6G01940
1 - - 0.0
98552
AFU_orthologue AFUA_3G09070
1 - - 0.0
16750
AFU_orthologue AFUA_2G08500
1 - - 0.0
98611
1 - - 0.0
73250
1 - - 0.0
63444
1
EC
- - 0.0
115853
1 - - 0.0
115748
1 - - 0.0
113860
1 - - 0.0
98829
1 - - 0.0
106637
1 - - 0.0
108681
1 - - 0.0
102530
1 - - 0.0
94301
1
EC
- - 0.0
51718
1
EC
- - 0.0
111446
AFU_orthologue AFUA_2G08500
1 - - 0.0
16336
AFU_orthologue AFUA_3G09070
1 - - 0.0
33617
1 - - 0.0
87070
1 - - 0.0
80550
3-hydroxyoctanoate
1
EC
- - 0.0
43329
1 - - 0.0
34823
1 - - 0.0
115453
1 - - 0.0
107605
1 - - 0.0
62138
1 - - 0.0
78270
1
EC
- - 0.0
110651
1 - - 0.0