The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ribosomal protein S10 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Ribosomal protein S10

This superfamily entry represents the ribosomal protein S10 found in the small subunit (50S) of the bacterial ribosome. The superfamily also includes S10 homologues found in other organisms, such as algal chloroplast S10, cyanelle S10, archaebacterial S10, Marchantia polymorpha and Prototheca wickerhamii mitochondrial S10, Arabidopsis thaliana mitochondrial S10 (nuclear encoded), vertebrate S20, plant S20 and yeast URP2. Structurally, this ribosomal protein is a whole chain domain and has a ferrodoxin-like fold, which consists of an alpha+beta sandwich with antiparallel beta-sheet.

The small ribosomal subunit protein S10 consists of about 100 amino acid residues. In Escherichia coli, S10 is involved in binding tRNA to the ribosome, and also operates as a transcriptional elongation factor.

In phages, S10 participates together with NusB protein (N-utilisation substance B) in processive transcription antitermination. NusE is identical to r-protein S10. In the transcriptionally active NusB-S10 complex, S10 adopts the same fold as in the 30S subunit and is blocked from simultaneous association with the ribosome. The molecular mechanisms by which S10 can act as a translation or a transcription factor are not understood yet.

PFAM:PF00338, INTERPRO:IPR036838,PMID:25271403

GO Diversity

Unique GO annotations
45 Unique GO terms

EC Diversity

Unique EC annotations
11 Unique EC terms

Species Diversity

Unique species annotations
14788 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 426
Domain clusters (>95% seq id): 25
Domain clusters (>35% seq id): 8
Unique PDBs: 404
Alignments
Structural Clusters (5A): 2
Structural Clusters (9A): 1
FunFam Clusters: 16
Function
Unique EC: 11
Unique GO: 45
Taxonomy
Unique Species: 14788