The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: BMC (bacterial microcompartment) domain

Hundreds of species of bacteria produce large subcellular organelles known as microcompartments (MCPs), which consist of metabolic enzymes encapsulated within proteinaceous shells reminiscent of viral capsids. For MCPs to function, substrates and products must move across their outer protein shell, which lacks any lipid-based membrane. 3D structures of the proteins that comprise MCP shells have revealed narrow pores through their centers that are the routes by which substrates enter (and products escape from) MCPs. The shells of MCPs are assembled primarily from a family of small proteins that have bacterial microcompartment (BMC) domains PMID:25713376.

This entry represents the BMC domain which is found in a variety of polyhedral organelle shell proteins (CcmK), including CsoS1A, CsoS1B and CsoS1C of Thiobacillus neapolitanus (Halothiobacillus neapolitanus) and their orthologs from other bacteria (INTERPRO:IPR000249) .

GO Diversity

Unique GO annotations
6 Unique GO terms

EC Diversity

Unique EC annotations
7 Unique EC terms

Species Diversity

Unique species annotations
2246 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 299
Domain clusters (>95% seq id): 29
Domain clusters (>35% seq id): 8
Unique PDBs: 46
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Unique EC: 7
Unique GO: 6
Unique Species: 2246