The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Band 7 domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Band 7 domain

This superfamily is made up of diverse membrane-bound proteins characterised by the presence of a conserved domain, the band-7 domain. Alternative names for this domain are SPFH or PHB domain. The exact function of this domain remains unknown although characterised members have revealed lipid-binding properties together with the ability to assemble into membrane-bound oligomers that form putative scaffolds (INTERPRO:IPR001107).

The name refers to human erythrocyte membrane proteins separated by SDS polyacrylamide gel electrophoresis which have been stained with coomassie blue

GO Diversity

Unique GO annotations
298 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
16795 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 32
Domain clusters (>95% seq id): 5
Domain clusters (>35% seq id): 4
Unique PDBs: 9
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 49
Unique EC:
Unique GO: 298
Unique Species: 16795