The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
ligand-binding face of the semaphorins, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
1052
3D
4gz8B02 - 83.9
2
568
3D
5hdbD01 - 94.8
3
357 - - 87.8
5
186
3D
4wk4B01 - 76.6
4
183 - - 71.2
6
173
3D
4fwwA02 - 84.5
7
166
3D
3okyB02 - 81.7
8
135 - - 81.5
9
132 - - 84.0
10
131 - - 84.0
12
108
3D
5e6uB01 - 84.2
11
100 - - 38.0
13
90
3D
3ol2A02 - 84.7
14
82 - - 70.1
15
79 - - 70.7
16
79 - - 92.3
17
72
3D
3nvqE02 - 77.9
18
59 - - 88.0
19
56 - - 85.1
20
54 - - 85.8
21
53 - - 78.2
22
48 - - 91.0
23
41 - - 72.5
24
30 - - 40.6
25
TM semaphorin
22 - - 58.2
26
TM semaphorin
20 - - 86.2
27
Ig TM semaphorin
16 - - 82.1
28
13 - - 51.9
29
11 - - 56.7
32
8 - - 78.9
31
8 - - 7.7
33
8 - - 14.5
30
Ig TM semaphorin
8 - - 67.9
35
7 - - 16.0
36
7 - - 60.2
37
7 - - 77.1
34
7 - - 2.3
39
6 - - 8.5
40
6 - - 11.7
41
6 - - 72.7
38
6 - - 13.6
45
4 - - 65.7
43
4 - - 2.3
44
4 - - 8.2
42
4 - - 5.8
46
3 - - 46.1
47
3 - - 6.0
51
2 - - 6.1
48
2 - - 0.0
55
2 - - 11.2
52
2 - - 0.0
53
2 - - 9.4
49
Ig TM semaphorin
2 - - 0.0
50
2 - - 41.0
56
2 - - 0.0
54
2 - - 0.0
71
1 - - 0.0
58
1 - - 0.0
61
1 - - 0.0
57
1 - - 0.0
74
1 - - 0.0
68
1 - - 0.0
64
1 - - 0.0
60
TM semaphorin
1 - - 0.0
69
1 - - 0.0
65
1 - - 0.0
63
1 - - 0.0
66
1 - - 0.0
59
1 - - 0.0
62
1 - - 0.0
72
1 - - 0.0
73
1 - - 0.0
67
1 - - 0.0
70
1 - - 0.0