The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Selenium-binding protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Selenium-binding protein

Selenium is an important nutrient and its levels inside must be regulated since the lack of selenium suppresses expression of various enzymes, which leads to cell abnormality and diseases but high concentrations are toxic to the cell because it adversely affects numerous cell metabolic pathways. Structural domains comprising this superfamily share the structure of the subunits that comprise the Seleniun-binding protein (SeBP) which meadiates selienium transport in the archaeal Methanococcales. SeBP is a symmetric homopentamer that sequesters selenium during transport and therefore regulates the level of free selenium in the cell, and delivers it specifically to the selenophosphate synthase enzyme PMID:18650445.

GO Diversity

Unique GO annotations
0 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
12 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 5
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Function
Unique EC:
Unique GO:
Taxonomy
Unique Species: 12