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CATH Superfamily 3.10.450.230

VirB8 protein

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
VirB8 protein
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: VirB8 protein

According to the literature, members of the structural domains which comprise this superfamily correspond to the structure of the bacterial virulence protein VirB8, a component of a DNA transporter. This protein is necessary for the stabilisation of the inner membrane protein VirB3 and it has cytoplasmic, transmembrane, and periplasmic regions. The latter interacts with VirB9, VirB10 and itself PMID:11371528. Another member of this superfamily is the TrbF protein family, involved in conjugal transfer.

This domain has a similar fold to the NTF2 protein (INTERPRO:IPR007430)

GO Diversity

Unique GO annotations
4 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
2343 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 53
Domain clusters (>95% seq id): 8
Domain clusters (>35% seq id): 4
Unique PDBs: 16
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 2
Function
Unique EC:
Unique GO: 4
Taxonomy
Unique Species: 2343