The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Phenylacetic acid degradation B

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Phenylacetic acid degradation B

Phenylacetyl-CoA monooxygenase (epoxidase) is a multicomponent enzyme, PaaABC(D)E, responsible for the hydroxylation of phenylacetate-CoA (PA-CoA), the second catabolic step in phenylacetic acid (PA) degradation PMID:9600981,PMID:9748275,PMID:21247899. In addition to catalysing this reaction which transforms phenylacetyl-CoA into its ring-1,2-epoxide, itmediates the NADPH-dependent removal of the epoxide oxygen, process which regenerates phenylacetyl-CoA with formation of water PMID:22398448.

Structural domains comprising this superfamily share the structure of the PaaB subunit, which is thought to act as an effector protein PMID:20660314.

GO Diversity

Unique GO annotations
2 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
3171 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Unique EC:
Unique GO: 2
Unique Species: 3171