The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Deoxyuridine triphosphatase (dUTPase)

This entry represents a distorted barrel domain found in deoxyuridine triphosphate nucleotidohydrolases and CTP deaminases. Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) cleaves dUTP into pyrophosphate and dUMP. Three different subunit organisations of dUTPases have been found: they are either monomers, dimers or trimers PMID:11375495. In the homotrimer, each subunit folds into a twisted antiparallel beta-barrel with the N and C-terminal portions interacting with adjacent subunits PMID:9878436.

PMID:11375495 PMID:9878436 (INTERPRO:IPR036157)

GO Diversity

Unique GO annotations
38 Unique GO terms

EC Diversity

Unique EC annotations
17 Unique EC terms

Species Diversity

Unique species annotations
14446 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 411
Domain clusters (>95% seq id): 39
Domain clusters (>35% seq id): 20
Unique PDBs: 140
Structural Clusters (5A): 3
Structural Clusters (9A): 3
FunFam Clusters: 18
Unique EC: 17
Unique GO: 38
Unique Species: 14446