The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Bacteriophage SPP1 head-tail adaptor protein
".
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"
In bacteriophage SPP1, the gp16 protein functions as a stopper, locking the viral DNA into the capsid. When the tail attachment binds to the entry receptor, gp16 opens by a diaphragm-like motion, allowing the genome to exit the capsid through the tail tube to the host cell. During virion assembly, gp16 functions as a docking platform to which the preassembled tail binds PMID:25991862.
The SPP1 head-to-tail connector is composed of cyclical dodecamers of the portal protein gp6 (subunit molecular mass of 57.3 kDa) and of the 2 head completion proteins gp15 (11.6 kDa) and gp16 (12.5 kDa) PMID:19433794.
| Structures | |
|---|---|
| Domains: | 2 |
| Domain clusters (>95% seq id): | 2 |
| Domain clusters (>35% seq id): | 2 |
| Unique PDBs: | 2 |
| Alignments | |
| Structural Clusters (5A): | 1 |
| Structural Clusters (9A): | 1 |
| FunFam Clusters: | 0 |
| Function | |
| Unique EC: | |
| Unique GO: | |
| Taxonomy | |
| Unique Species: | 3178 |