The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Alpha-1-antitrypsin, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
48
Serine protease inhibitor
1700
EC
3D
1a7cA02 - 87.9
4513
1581
EC
3D
2zv6A02 - 92.5
4716
Serine proteinase inhibitor
1480
EC
3D
2hi9C02 - 94.4
4550
Serine protease inhibitor
725
EC
3D
3le2A02 - 92.6
254
Serpin family
514
EC
3D
1antI01 - 92.0
4674
312 - - 90.0
4524
281 - - 96.5
4491
209
3D
1as4A01 - 96.3
4442
175 - - 88.5
4434
172
3D
1atuA01 - 76.6
4309
137
3D
4dy0A02 - 71.0
4401
126
3D
1imvA01 - 75.0
4375
117
3D
2ceoA02 - 85.0
128
105
3D
3f02A02 - 66.4
4566
92 - - 88.2
4459
83
3D
3zhaA02 - 31.5
177
82 - - 84.6
4405
66 - - 75.5
131
61 - - 51.4
4313
60 - - 54.4
4385
59
3D
1jmjA02 - 38.9
4483
42 - - 72.9
907
41
3D
3pzfA01 - 68.5
4638
39
3D
2wxxA01 - 91.0
4596
33
3D
2oayA02 - 47.0
781
28
3D
1c8oA02 - 16.0
4645
Serpin family
27 - - 75.9
93
20
3D
2wxwA01 - 24.8
4629
15 - - 71.0
4486
13 - - 72.0
1788
11 - - 10.1
4440
11 - - 47.5
4611
11 - - 25.8
4688
10
3D
5c98A02 - 57.0
206
9 - - 35.5
4650
SERPIN
9 - - 80.1
667
7 - - 44.2
4267
7 - - 35.2
4378
6 - - 1.7
2116
6 - - 7.3
1084
5 - - 13.3
2343
5 - - 10.8
4487
5 - - 59.4
161
4 - - 0.0
2828
3 - - 0.0
693
3 - - 25.7
4310
3 - - 0.0
4686
3 - - 6.3
4538
3 - - 0.0
1745
3 - - 12.3
717
3 - - 14.8
4616
3 - - 37.6
4684
2 - - 41.6
1206
2 - - 16.4
582
2 - - 2.8
4343
2 - - 0.0
130
2 - - 12.6
4379
1 - -
58
1 - - 0.0
754
1 - -
4261
1 - - 0.0
159
1 - -
1427
1 - - 0.0
4584
1 - - 0.0
4603
1 - - 0.0
4582
Or cysteine
1 - - 0.0
1195
1 - - 0.0
228
1 - - 0.0
282
1 - - 0.0
344
1 - - 0.0
2475
1 - - 0.0
4691
1 - - 0.0
4301
1 - - 0.0
75
1 - - 0.0
2253
- -