The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

SLA1 homology domain 1

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: SLA1 homology domain 1

Structural domains comprising this superfamily share the structure of the The SLA1 homology domain (SHD1) is found in the cytoskeleton assembly control protein SLA1, which serves as the adaptor for uptake of transmembrane proteins containing the NPFxD internalization signal, and is essential for normal functioning of the actin cytoskeleton during endocytosis. SHD1 specifically recognises NPFxD-type internalization signals found in the cytoplasmic domains of transmembrane proteins PMID:17363896.

GO Diversity

Unique GO annotations
21 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
843 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Unique EC:
Unique GO: 21
Unique Species: 843