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CATH Superfamily 2.170.16.10

Hedgehog/Intein (Hint) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Hedgehog/Intein (Hint) domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Indian hedgehog
194
3D
 1at0A00 - 93.8
2
Desert hedgehog
74 - - 92.2
3
Homothallism endonuclease
17 - - 16.0
4
Replicative DNA helicase DnaB
14 - - 2.6
7
Protein RecA
11
3D
 2imzB00 - 19.6
5
Replicative DNA helicase
11 - - 2.8
6
UPF0051 protein Mb1496
10 - - 3.7
8
Protein RecA
8 - - 0.0
9
Pre-mRNA splicing factor
Prp8
7 - - 28.8
10
Ataxin 1-like
6 - - 75.2
11
Pre-mRNA-processing-splicing factor 8
5 - - 9.6
29
DNA polymerase
4
3D
 2cw8A01 - 4.5
15
DNA-directed RNA polymerase subunit beta
4 - - 5.2
14
DNA-directed RNA polymerase subunit beta
4 - - 7.6
12
Replication factor C small subunit
4 - - 39.4
13
Replication factor C small subunit
4 - - 82.2
16
GRounDhog
Hedgehog-like family
3 - - 76.5
23
Replication factor C small subunit
2 - - 42.3
21
Replication factor C small subunit
2 - - 32.9
22
Ribonucleoside-diphosphate reductase
2 - - 34.5
27
Replicative DNA helicase
2 - - 0.8
20
Probable translation initiation factor IF-2
2 - - 35.2
17
Uncharacterized protein
2 - - 0.0
26
MCM / cell division control protein 21
2 - - 0.0
28
NAD
P +
2 - - 0.0
24
Replicative DNA helicase
2 - - 0.0
25
Hedgehog protein
2 - - 0.7
18
DNA-directed RNA polymerase III subunit rpc2
2 - - 30.6
19
Probable translation initiation factor IF-2
2 - - 31.5
30
Transcriptional regulator, XRE family
2 - - 5.1
32
Uncharacterized protein
1 - - 0.0
31
DNA polymerase II large subunit
1 - - 0.0
49
ATP-dependent DNA helicase Hel308
1 - - 0.0
43
DNA-directed RNA polymerase subunit beta
1 - - 0.0
39
Transcription initiation factor IIB
1 - - 0.0
45
Gll3966 protein
1 - - 0.0
42
Replicative DNA helicase
1 - - 0.0
51
DNA gyrase subunit A
1 - - 0.0
33
XK-related protein
1 - - 0.0
48
DNA replication licensing factor, MCM2/3/5 family
1 - - 0.0
50
DNA gyrase subunit B
1 - - 0.0
40
DNA polymerase III subunit
1 - - 0.0
34
Hedgehog protein
1 - - 0.0
35
DNA topoisomerase 1
1 - - 0.0
47
ATP-dependent DNA helicase Hel308
1 - - 0.0
37
Large helicase-related protein
1 - - 0.0
41
Vitamin B12-dependent ribonucleotide reductase
1 - - 0.0
46
Replication factor C small subunit
1 - - 0.0
36
ATP-dependent DNA helicase Hel308
1 - - 0.0
44
DNA topoisomerase 1
1 - - 0.0
38
Vitamin B12-dependent ribonucleotide reductase
1 - - 0.0