The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TolB, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
700
3D
6h16A01 - 91.1
2
639
3D
3p5bL02 - 85.0
3
614 - - 80.9
4
543 - - 55.8
5
518 - - 87.8
6
479 - - 92.9
7
437 - - 72.4
8
423
3D
3v65D02 - 88.3
9
385 - - 80.4
10
382 - - 78.6
11
365 - - 78.0
12
340 - - 92.0
13
334 - - 92.0
14
308 - - 72.0
15
291 - - 78.7
17
278
3D
6h16A02 - 82.8
16
270
3D
3fw0A00 - 88.6
18
251 - - 69.4
19
235 - - 71.2
22
222
3D
3iaxA02 - 53.0
20
217 - - 80.9
21
202 - - 77.3
23
194
3D
1v04A00 - 89.4
24
189
3D
4dg6A01 - 68.4
27
166
3D
4gnaB00 - 94.0
25
161 - - 71.3
26
149 - - 73.3
28
128 - - 74.0
29
127 - - 33.6
30
126
3D
1npeA00 - 71.4
31
116
3D
5ex7A00 - 40.8
32
105 - - 92.8
33
104 - - 79.6
34
97 - - 47.5
35
90 - - 94.0
37
87 - - 97.3
36
87 - - 94.3
38
81 - - 83.7
39
76 - - 46.9
40
76 - - 78.6
41
73 - - 72.4
42
63 - - 86.9
43
62 - - 85.3
44
61 - - 94.9
45
61 - - 98.4
46
60 - - 88.2
47
56 - - 53.6
48
55 - - 90.9
49
51 - - 68.2
50
50 - - 34.5
51
48 - - 60.2
52
47 - - 1.0
53
45 - - 85.2
55
44 - - 83.8
54
44 - - 85.7
56
43 - - 49.2
57
43 - - 66.0
60
40 - - 79.9
58
40 - - 56.6
59
40 - - 60.3
61
39 - - 46.3
62
38 - - 69.9
63
33 - - 73.6
64
33 - - 98.0
65
30 - - 83.4
66
27 - - 95.1
67
26 - - 76.3
68
25 - - 53.0
69
23 - - 22.2
70
23 - - 50.9
71
22 - - 76.8
72
22 - - 22.4
73
22 - - 82.5
76
21 - - 64.7
74
21 - - 25.6
75
21 - - 67.7
78
19 - - 25.3
77
19 - - 6.9
80
17 - - 81.8
79
17 - - 83.8
82
16 - - 25.1
84
16 - - 60.1
81
16 - - 74.0
83
16 - - 92.5
85
15 - - 28.4
89
14 - - 90.0
90
14 - - 12.2
87
14 - - 20.8
91
14 - - 20.9
86
14 - - 68.9
88
14 - - 21.6
92
13 - - 74.3
94
13 - - 78.9
93
13 - - 82.1
95
13 - - 93.1
99
12 - - 2.7
96
12 - - 70.3
98
12 - - 17.6
102
12 - - 88.2
100
12 - - 25.6
101
12 - - 64.5
97
12 - - 17.0
105
11 - - 33.4
103
11 - - 40.1
109
11 - - 74.7
107
11 - - 95.7
108
11 - - 79.6
106
11 - - 14.0
104
11 - - 34.3
112
10 - - 86.4
110
10 - - 71.6
115
Basement membrane protein
10 - - 12.1
111
10 - - 23.5
113
10 - - 19.4
116
10 - - 0.0
114
10 - - 15.7
119
9 - - 9.3
117
9 - - 46.0
121
9 - - 16.5
123
9 - - 43.9
118
9 - - 14.6
120
9 - - 0.0
122
9 - - 22.5
124
8 - - 11.1
126
8 - - 37.0
128
8 - - 90.4
479
8
3D
3o4pA00 - 0.0
125
8 - - 0.0
127
8 - - 79.5
129
7 - - 30.7
131
7 - - 81.1
141
7 - - 18.7
133
7 - - 13.7
137
7 - - 17.8
135
7 - - 7.8
130
7 - - 40.9
140
7 - - 8.1
132
7 - - 90.1
139
7 - - 32.9
134
7 - - 18.3
136
7 - - 13.6
138
7 - - 14.9
148
6 - - 0.0
143
6 - - 24.3
147
6 - - 12.4
145
6 - - 20.8
150
6 - - 36.3
142
6 - - 75.5
149
6 - - 2.2
144
6 - - 82.6
146
6 - - 13.3
151
6 - - 66.0
170
5 - - 60.1
165
5 - - 12.2
168
5 - - 13.2
157
5 - - 12.1
163
5 - - 64.2
154
5 - - 32.4
152
5 - - 67.0
160
5 - - 17.5
167
5 - - 74.6
159
5 - - 0.0
162
5 - - 54.7
169
5 - - 54.1
158
5 - - 2.4
156
5 - - 5.5
166
5 - - 5.5
153
5 - - 16.1
155
5 - - 11.8
161
5 - - 23.5
164
5 - - 73.3
184
4 - - 14.1
181
4 - - 8.8
192
4 - - 65.3
199
4 - - 82.9
179
4 - - 7.8
193
4 - - 76.0
186
4 - - 0.0
176
4 - - 78.1
180
4 - - 7.5
187
4 - - 8.0
175
4 - - 25.1
200
4 - - 89.4
189
4 - - 68.2
182
4 - - 12.9
197
4 - - 88.2
190
4 - - 68.9
172
4 - - 85.0
191
4 - - 50.0
178
4 - - 0.0
183
4 - - 6.5
177
4 - - 29.5
196
4 - - 90.4
194
4 - - 47.2
171
4 - - 72.2
185
4 - - 0.0
198
DLR class
4 - - 82.4
195
4 - - 84.4
174
4 - - 43.2
188
4 - - 21.8
173
Ring finger b-box coiled coil
4 - - 4.8
232
3 - - 36.1
207
3 - - 40.7
224
3 - - 1.5
234
3 - - 0.0
205
3 - - 46.8
226
3 - - 12.1
237
3 - - 51.2
215
3 - - 2.7
212
3 - - 13.5
202
3 - - 32.5
242
3 - - 48.0
228
3 - - 10.7
211
3 - - 3.2
218
3 - - 53.1
221
3 - - 73.5
240
3 - - 43.3
230
3 - - 16.6
239
3 - - 70.8
206
3 - - 74.6
223
3 - - 0.0
216
3 - - 1.8
225
3 - - 0.0
222
3 - - 8.9
217
3 - - 25.5
209
3 - - 2.6
233
3 - - 0.0
204
3 - - 30.4
236
3 - - 0.0
227
3 - - 1.3
214
3 - - 9.7
235
3 - - 10.3
229
3 - - 69.0
210
3 - - 11.4
213
3 - - 14.2
243
3 - - 25.8
203
3 - - 35.7
238
3 - - 35.7
219
3 - - 63.3
220
3 - - 42.2
208
3 - - 6.7
241
3 - - 40.0
201
3 - - 5.4
231
3 - - 10.0
294
2 - - 1.7
326
2 - - 0.9
305
2 - - 40.8
281
2 - - 8.2
319
2 - - 9.5
336
2 - - 0.0
365
2 - - 39.2
252
2 - - 33.6
351
2 - - 36.9
279
2 - - 0.0
263
2 - - 37.7
310
2 - - 0.0
273
2 - - 0.8
334
2 - - 40.8
371
2 - - 9.0
345
2 - - 0.0
258
2 - - 26.6
248
2 - - 0.0
288
2 - - 3.1
264
2 - - 39.1
320
2 - - 5.8
338
2 - - 0.0
328
2 - - 25.9
297
2 - - 32.2
283
2 - - 7.0
300
2 - - 37.0
256
2 - - 35.0
270
2 - - 1.8
343
2 - - 0.0
261
2 - - 38.9
285
2 - - 2.8
366
2 - - 39.2
323
2 - - 0.0
257
DLR class
2 - - 34.3
361
2 - - 46.1
307
2 - - 1.3
299
2 - - 37.4
247
2 - - 0.0
289
2 - - 1.6
290
2 - - 0.0
341
2 - - 0.0
309
2 - - 0.7
254
2 - - 0.0
372
2 - - 31.9
354
2 - - 38.8
316
2 - - 0.0
314
2 - - 0.0
302
2 - - 39.6
356
2 - - 34.1
325
2 - - 4.5
287
2 - - 1.3
333
2 - - 39.2
274
2 - - 7.6
250
osteonidogen
2 - - 7.2
276
2 - - 8.7
269
2 - - 7.7
363
SodC
2 - - 37.2
358
2 - - 41.1
331
2 - - 14.0
348
2 - - 0.0
312
2 - - 0.0
370
2 - - 40.1
245
2 - - 1.9
368
2 - - 42.0
327
2 - - 14.5
266
2 - - 0.0
304
2 - - 37.2
350
2 - - 38.8
311
2 - - 0.7
272
2 - - 0.0
262
2 - - 44.2
359
2 - - 42.5
278
2 - - 9.6
335
2 - - 0.0
344
2 - - 2.1
329
2 - - 37.7
346
2 - - 0.0
293
2 - - 2.1
267
2 - - 0.7
280
2 - - 3.9
362
2 - - 38.8
253
2 - - 23.3
318
2 - - 0.0
337
2 - - 0.0
260
2 - - 0.0
259
2 - - 37.4
249
2 - - 23.2
364
2 - - 22.8
244
2 - - 7.7
295
2 - - 23.3
296
2 - - 13.2
265
2 - - 39.5
352
2 - - 35.5
321
2 - - 4.0
282
2 - - 1.0
306
2 - - 0.0
340
2 - - 0.0
246
2 - - 1.5
308
2 - - 2.9
301
2 - - 34.5
349
2 - - 34.7
330
2 - - 36.3
360
2 - - 39.7
353
2 - - 41.2
315
2 - - 8.7
317
2 - - 0.0
284
2 - - 0.0
271
2 - - 0.0
367
2 - - 47.0
342
2 - - 0.0
322
2 - - 1.8
355
2 - - 36.4
298
2 - - 36.1
339
2 - - 0.0
268
2 - - 4.4
255
2 - - 38.6
303
2 - - 41.6
347
2 - - 0.0
313
2 - - 8.0
357
2 - - 42.4
324
2 - - 0.0
286
2 - - 0.0
275
2 - - 0.0
251
2 - - 29.2
369
2 - - 41.9
332
2 - - 35.7
292
2 - - 0.0
291
2 - - 1.9
277
2 - - 1.1
558
1 - - 0.0
506
1 - - 0.0
581
1 - - 0.0
468
1 - - 0.0
413
1 - - 0.0
588
1 - - 0.0
542
1 - - 0.0
526
1 - - 0.0
490
1 - - 0.0
461
1 - - 0.0
412
1 - - 0.0
474
1 - - 0.0
600
1 - - 0.0
457
1 - - 0.0
383
1 - - 0.0
419
1 - - 0.0
570
1 - - 0.0
408
1 - - 0.0
431
1 - - 0.0
405
1 - - 0.0
392
1 - - 0.0
427
1 - - 0.0
426
1 - - 0.0
483
1 - - 0.0
533
1 - - 0.0
603
1 - - 0.0
565
1 - - 0.0
471
1 - - 0.0
562
1 - - 0.0
439
1 - - 0.0
376
1 - - 0.0
609
1 - - 0.0
624
1 - - 0.0
613
1 - - 0.0
560
1 - - 0.0
451
1 - - 0.0
540
1 - - 0.0
594
1 - - 0.0
415
1 - - 0.0
519
1 - - 0.0
556
1 - - 0.0
549
1 - - 0.0
583
1 - - 0.0
591
1 - - 0.0
465
1 - - 0.0
385
1 - - 0.0
621
1 - - 0.0
576
1 - - 0.0
401
1 - - 0.0
437
1 - - 0.0
579
1 - - 0.0
496
1 - - 0.0
605
1 - - 0.0
441
1 - - 0.0
394
1 - - 0.0
374
1 - - 0.0
429
1 - - 0.0
489
1 - - 0.0
622
1 - - 0.0
478
1 - - 0.0
531
1 - - 0.0
420
1 - - 0.0
618
1 - - 0.0
512
1 - - 0.0
463
1 - - 0.0
517
1 - - 0.0
391
1 - - 0.0
456
1 - - 0.0
477
1 - - 0.0
449
1 - - 0.0
387
1 - - 0.0
539
1 - - 0.0
520
1 - - 0.0
584
1 - - 0.0
554
1 - - 0.0
552
1 - - 0.0
546
1 - - 0.0
537
1 - - 0.0
529
1 - - 0.0
597
1 - - 0.0
443
1 - - 0.0
509
1 - - 0.0
568
1 - - 0.0
615
1 - - 0.0
476
1 - - 0.0
575
1 - - 0.0
502
1 - - 0.0
423
1 - - 0.0
422
1 - - 0.0
435
1 - - 0.0
487
1 - - 0.0
396
1 - - 0.0
482
1 - - 0.0
499
1 - - 0.0
450
1 - - 0.0
454
1 - - 0.0
389
1 - - 0.0
586
1 - - 0.0
410
1 - - 0.0
480
1 - - 0.0
417
1 - - 0.0
381
1 - - 0.0
515
1 - - 0.0
510
1 - - 0.0
393
1 - - 0.0
524
1 - - 0.0
598
1 - - 0.0
544
1 - - 0.0
522
1 - - 0.0
459
1 - - 0.0
404
1 - - 0.0
550
1 - - 0.0
592
1 - - 0.0
572
1 - - 0.0
379
1 - - 0.0
535
1 - - 0.0
567
1 - - 0.0
445
1 - - 0.0
617
1 - - 0.0
589
1 - - 0.0
611
1 - - 0.0
492
1 - - 0.0
433
1 - - 0.0
497
1 - - 0.0
398
1 - - 0.0
601
1 - - 0.0
504
1 - - 0.0
458
1 - - 0.0
495
1 - - 0.0
486
1 - - 0.0
573
1 - - 0.0
606
IV
1 - - 0.0
432
1 - - 0.0
425
1 - - 0.0
532
1 - - 0.0
395
1 - - 0.0
440
1 - - 0.0
467
1 - - 0.0
563
1 - - 0.0
472
1 - - 0.0
505
1 - - 0.0
406
1 - - 0.0
559
1 - - 0.0
580
1 - - 0.0
382
1 - - 0.0
523
1 - - 0.0
453
1 - - 0.0
595
1 - - 0.0
507
1 - - 0.0
525
1 - - 0.0
498
1 - - 0.0
414
1 - - 0.0
462
1 - - 0.0
469
1 - - 0.0
543
1 - - 0.0
616
1 - - 0.0
407
1 - - 0.0
473
1 - - 0.0
578
1 - - 0.0
571
1 - - 0.0
430
1 - - 0.0
447
1 - - 0.0
438
1 - - 0.0
493
1 - - 0.0
400
1 - - 0.0
442
1 - - 0.0
619
1 - - 0.0
377
1 - - 0.0
602
1 - - 0.0
612
1 - - 0.0
484
1 - - 0.0
623
1 - - 0.0
608
1 - - 0.0
397
1 - - 0.0
561
1 - - 0.0
530
1 - - 0.0
470
1 - - 0.0
527
1 - - 0.0
548
1 - - 0.0
460
1 - - 0.0
452
1 - - 0.0
541
1 - - 0.0
416
1 - - 0.0
582
1 - - 0.0
557
1 - - 0.0
590
1 - - 0.0
428
1 - - 0.0
500
1 - - 0.0
513
1 - - 0.0
620
1 - - 0.0
409
1 - - 0.0
585
1 - - 0.0
518
1 - - 0.0
384
1 - - 0.0
577
1 - - 0.0
466
1 - - 0.0
569
1 - - 0.0
536
1 - - 0.0
444
1 - - 0.0
508
1 - - 0.0
545
1 - - 0.0
574
1 - - 0.0
566
1 - - 0.0
604
IV
1 - - 0.0
375
1 - - 0.0
501
1 - - 0.0
481
1 - - 0.0
421
1 - - 0.0
491
1 - - 0.0
488
1 - - 0.0
399
1 - - 0.0
436
1 - - 0.0
386
1 - - 0.0
511
1 - - 0.0
553
1 - - 0.0
555
1 - - 0.0
593
1 - - 0.0
402
1 - - 0.0
464
1 - - 0.0
599
1 - - 0.0
587
1 - - 0.0
596
1 - - 0.0
494
1 - - 0.0
448
1 - - 0.0
547
1 - - 0.0
528
1 - - 0.0
378
1 - - 0.0
373
1 - - 0.0
534
1 - - 0.0
475
1 - - 0.0
446
1 - - 0.0
614
1 - - 0.0
424
1 - - 0.0
434
1 - - 0.0
564
1 - - 0.0
503
1 - - 0.0
516
1 - - 0.0
455
1 - - 0.0
390
1 - - 0.0
418
1 - - 0.0
388
1 - - 0.0
485
1 - - 0.0
380
1 - - 0.0
607
1 - - 0.0
514
1 - - 0.0
610
1 - - 0.0
538
1 - - 0.0
521
1 - - 0.0
411
1 - - 0.0
551
1 - - 0.0
403
1 - - 0.0