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CATH Superfamily 2.10.50.10

Tumor Necrosis Factor Receptor, subunit A, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Tumor Necrosis Factor Receptor, subunit A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Ephrin type-A receptor 5
1934
3D
 4m4rE03 - 96.8
2
signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1
277 - - 87.0
4
Tumor necrosis factor receptor superfamily member 6
211
3D
 3tjeF02 - 92.7
3
Tumor necrosis factor receptor superfamily member 19
193 - - 86.2
5
signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1
180 - - 72.6
6
Signal peptide, CUB domain and EGF like domain containing 3
153 - - 81.1
7
TNF receptor superfamily member 14
149
3D
 4rsuL01 - 95.2
9
Tumor necrosis factor receptor superfamily member 14
140
3D
 4rsuL02 - 97.2
8
Signal peptide, CUB domain and EGF-like domain-containing 3
133 - - 62.4
10
Tumor necrosis factor receptor superfamily member 21
128
3D
 4yn0A01 - 74.7
11
Tumor necrosis factor receptor superfamily member 21
118
3D
 4yn0A02 - 91.8
12
tumor necrosis factor receptor superfamily member 16
108
3D
 3ij2Y02 - 67.7
17
Tumor necrosis factor receptor superfamily member 10B
106
3D
 5cirG01 - 69.8
14
Tumor necrosis factor receptor superfamily member 11B
103
3D
 3urfZ02 - 68.6
13
Tumor necrosis factor receptor superfamily member 16
102
3D
 3ij2Y01 - 66.3
15
TNF receptor superfamily member 11a
93
3D
 5bnqR02 - 40.5
16
Tumor necrosis factor receptor superfamily member 10B
92
3D
 1du3G02 - 92.4
19
Tumor necrosis factor receptor superfamily member 11A
79
3D
 5bnqR01 - 29.1
18
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing 1
78 - - 97.1
20
Tumor necrosis factor receptor superfamily member 1A
76
3D
 1tnrR01 - 87.1
21
Tumor necrosis factor receptor superfamily member 6
69
3D
 3tjeF01 - 70.9
25
Tumor necrosis factor receptor superfamily member 1A
68
3D
 1tnrR02 - 88.1
22
Signal peptide, CUB domain and EGF-like domain-containing 1
63 - - 64.4
26
Tumor necrosis factor receptor superfamily member 4
63
3D
 2heyT02 - 91.0
23
Ectodysplasin A receptor
63 - - 34.5
24
signal peptide, CUB and EGF-like domain-containing protein 1
63 - - 72.9
27
tumor necrosis factor receptor superfamily member 16
56 - - 84.0
28
Signal peptide, CUB domain and EGF like domain containing 2
48 - - 45.8
31
Tumor necrosis factor receptor superfamily member 1B
46
3D
 3alqW01 - 51.1
29
Signal peptide, CUB domain and EGF like domain containing 2
45 - - 84.5
30
Tumor necrosis factor receptor superfamily member 11B
44
3D
 3urfZ01 - 77.5
36
Tumor necrosis factor receptor superfamily member 1B
37
3D
 3alqW02 - 82.5
32
Uncharacterized protein, isoform A
37 - - 91.0
33
CD27 molecule
36 - - 82.4
35
Tumor necrosis factor receptor superfamily member 3
34
3D
 4mxwR02 - 50.1
34
TNF receptor superfamily member 25
34 - - 37.8
43
Tumor necrosis factor receptor superfamily member 5
33
3D
 5ihlH01 - 47.5
38
Tumor necrosis factor receptor superfamily member 4
31
3D
 2heyT01 - 79.6
37
Uncharacterized protein, isoform A
31 - - 61.1
39
Tumor necrosis factor receptor superfamily member 19L
28 - - 77.0
40
Tumor necrosis factor receptor superfamily member 14
27 - - 88.8
41
Tumor necrosis factor receptor superfamily member 5
26 - - 86.7
42
Signal peptide, CUB domain and EGF like domain containing 2
23 - - 43.4
44
Tumor necrosis factor receptor superfamily member 5
21 - - 9.2
46
Cysteine repeat modular protein 1
20 - - 12.7
45
Cysteine repeat modular protein 2
20 - - 47.0
47
Thyroglobulin
20 - - 89.6
51
Cysteine repeat modular protein 1
19 - - 5.2
48
Cysteine repeat modular protein 1
19 - - 9.9
53
Predicted protein
19 - - 82.9
49
Cysteine repeat modular protein 2 PbCRM2
19 - - 11.4
50
Cysteine repeat modular protein 1
19 - - 9.9
52
Cysteine repeat modular protein 1
19 - - 1.9
81
Tumor necrosis factor receptor superfamily member 6B
19
3D
 5l36B01 - 16.6
54
UPF0577 protein KIAA1324 homolog
19 - - 34.2
55
Cysteine repeat modular protein 2 PbCRM2
18 - - 3.9
56
Cysteine repeat modular protein 2 PbCRM2
18 - - 3.6
58
Cysteine repeat modular protein 4 PbCRM4
17 - - 6.5
61
Cysteine repeat modular protein 3
17 - - 10.3
57
Cysteine repeat modular protein 4 PbCRM4
17 - - 2.1
59
TNF receptor superfamily member 8
17 - - 14.9
62
Cysteine repeat modular protein 1
17 - - 6.9
60
Tumor necrosis factor receptor superfamily member 3
17 - - 19.8
63
signal peptide, CUB and EGF-like domain-containing protein 3 isoform X4
17 - - 73.8
64
Cysteine repeat modular protein 3
16 - - 18.1
74
Tumor necrosis factor receptor superfamily member 5
14
3D
 3qd6U02 - 12.6
66
Cysteine repeat modular protein 3
13 - - 10.6
65
TNF receptor superfamily member 14
13 - - 85.2
71
Cysteine repeat modular protein 2
12 - - 71.8
68
Cysteine repeat modular protein 4 PbCRM4
12 - - 4.2
69
Cysteine repeat modular protein 3
12 - - 2.0
67
Tumor necrosis factor receptor superfamily member 14
12 - - 27.9
70
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1
12 - - 64.6
72
TNF receptor superfamily member 8
11 - - 15.2
73
TNF receptor superfamily member 9
11 - - 45.6
76
Neurotrophin receptor associated death domain
10 - - 87.1
77
Ectodysplasin A receptor
10 - - 41.4
75
Neurotrophin receptor associated death domain
10 - - 85.8
78
Tumor necrosis factor receptor superfamily member 3
9 - - 38.1
80
Uninflatable, isoform C
9 - - 4.6
79
tumor necrosis factor receptor superfamily member 3
9 - - 47.3
82
Zinc finger domain LSD1 subclass family protein
8 - - 73.5
87
Tumor necrosis factor receptor superfamily member 23
6 - - 85.7
85
Nerve growth factor receptor b
6 - - 41.7
84
Tumor necrosis factor receptor superfamily member 18
6 - - 34.0
83
TNF receptor superfamily member 10c
6 - - 0.0
86
Predicted protein
6 - - 95.3
89
Neurotrophin receptor associated death domain
5 - - 52.0
91
EPH receptor B6
5 - - 78.3
92
Predicted protein
5 - - 43.7
90
signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1
5 - - 75.6
93
Nerve growth factor receptor
5 - - 0.0
88
Si:ch211-261n11.7
5 - - 76.9
96
Hematopoietic death receptor
4 - - 2.1
98
C-type LECtin
4 - - 79.1
94
Predicted protein
4 - - 6.1
97
Tumor necrosis factor receptor superfamily, member 1a
4 - - 10.8
95
Ovarian TNF receptor
4 - - 2.0
101
Uncharacterized protein
3 - - 0.0
102
Uncharacterized protein
3 - - 0.0
105
TvbS1
3 - - 0.0
100
Zgc:163064 protein
3 - - 8.3
99
Zgc:163064 protein
3 - - 8.4
104
TvbS1
3 - - 0.0
103
DNA topoisomerase I
3 - - 82.9
127
C-type LECtin
2 - - 6.6
119
Predicted protein
2 - - 43.1
107
Tumor necrosis factor receptor superfamily member 5
2 - - 19.4
116
Predicted protein
2 - - 40.5
110
Predicted protein
2 - - 48.5
112
Tumor necrosis factor receptor superfamily member 6
2 - - 0.0
108
Si:ch211-261n11.8
2 - - 3.3
128
Tumor necrosis factor receptor superfamily, member 1a
2 - - 0.0
130
Tumor necrosis factor receptor superfamily, member 1a
2 - - 0.0
115
Tumor necrosis factor receptor superfamily member 6
2 - - 0.0
122
Ephrin receptor like protein
2 - - 5.4
132
signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1
2 - - 0.0
125
signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1
2 - - 2.2
117
Uncharacterized protein
2 - - 48.0
111
Fas cell surface death receptor
2 - - 9.4
118
Predicted protein
2 - - 46.8
129
Tumor necrosis factor receptor superfamily, member 1a
2 - - 3.1
124
Death receptor 6
2 - - 0.0
113
Uncharacterized protein
2 - - 0.0
120
Uncharacterized protein
2 - - 43.5
109
Si:ch211-261n11.7
2 - - 0.0
126
Uncharacterized protein
2 - - 10.6
114
Fas cell surface death receptor
2 - - 0.0
131
Tumor necrosis factor receptor superfamily, member 1a
2 - - 3.5
106
Si:ch211-261n11.8
2 - - 7.8
121
Tumor necrosis factor receptor superfamily, member 1a
2 - - 0.0
133
Ephrin type-B receptor 5
2 - - 0.0
123
Uncharacterized protein
2 - - 11.8
134
Tumor necrosis factor receptor superfamily, member 11b
2 - - 45.7
153
Predicted protein
1 - - 0.0
160
Predicted protein
1 - - 0.0
136
Zgc:153759
1 - - 0.0
144
Uncharacterized protein
1 - - 0.0
151
Si:ch211-112c15.8
1 - - 0.0
138
Tumor necrosis factor receptor superfamily, member 11b
1 - - 0.0
137
CD40 molecule, TNF receptor superfamily member 5
1 - - 0.0
170
Predicted protein
1 - - 0.0
142
Predicted protein
1 - - 0.0
167
Uncharacterized protein
1 - - 0.0
155
Uncharacterized protein
1 - - 0.0
163
Uncharacterized protein
1 - - 0.0
140
TNF receptor superfamily member 10c
1 - - 0.0
154
Uncharacterized protein
1 - - 0.0
158
Uncharacterized protein
1 - - 0.0
165
Predicted protein
1 - - 0.0
147
Tumor necrosis factor receptor superfamily member 8
1 - - 0.0
149
Tumor necrosis factor receptor superfamily member 10B
1 - - 0.0
173
Uncharacterized protein
1 - - 0.0
156
Uncharacterized protein
1 - - 0.0
139
CD40 molecule, TNF receptor superfamily member 5
1 - - 0.0
168
Nerve growth factor receptor a
TNFR superfamily, member 16
1 - - 0.0
135
TNF receptor superfamily member 10d
1 - - 0.0
145
Uncharacterized protein
1 - - 0.0
152
Predicted protein
1 - - 0.0
171
Predicted protein
1 - - 0.0
161
Predicted protein
1 - - 0.0
150
Predicted protein
1 - - 0.0
159
Predicted protein
1 - - 0.0
162
Uncharacterized protein
1 - - 0.0
174
Uncharacterized protein
1 - - 0.0
143
Ectodysplasin A2 receptor
1 - - 0.0
169
Neurotrophin receptor-associated death domain
1 - - 0.0
148
Tumor necrosis factor receptor superfamily member 1A
1 - - 0.0
157
Uncharacterized protein
1 - - 0.0
172
Predicted protein
1 - - 0.0
166
Predicted protein
1 - - 0.0
141
CD27 molecule
1 - - 0.0
146
Uncharacterized protein
1 - - 0.0
164
IGF-like family receptor 1
1 - - 0.0