The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial carrier domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
604
3D
4c9hB00 - 77.5
2
598
3D
2c3eA00 - 93.3
3
586 - - 90.8
4
571 - - 86.4
5
382 - - 89.0
6
297 - - 89.2
7
234 - - 93.6
8
210
3D
2lckA00 - 82.0
9
202 - - 92.2
10
Mitochondrial carrier
193 - - 71.2
11
184 - - 92.2
12
182 - - 71.1
13
180 - - 83.0
14
172 - - 82.5
15
153 - - 92.3
16
149 - - 94.7
17
146 - - 70.9
18
139 - - 93.0
19
125 - - 78.5
20
120 - - 71.6
21
110 - - 77.0
22
103 - - 65.7
23
96 - - 64.6
24
93 - - 82.2
25
90 - - 88.9
26
88 - - 77.0
27
88 - - 74.5
28
85 - - 74.3
29
80 - - 89.3
30
79 - - 77.1
31
78 - - 72.5
33
77 - - 29.6
32
77 - - 66.8
34
76 - - 80.6
36
75 - - 76.8
37
75 - - 85.1
35
75 - - 77.3
39
74 - - 85.7
38
74 - - 68.3
40
72 - - 76.7
41
71 - - 78.9
42
68 - - 70.0
43
67 - - 68.3
44
64 - - 69.9
46
64 - - 77.4
45
64 - - 49.8
48
62 - - 38.5
47
62 - - 76.3
49
61 - - 91.3
50
60 - - 67.6
51
60 - - 77.1
52
55 - - 40.6
53
55 - - 75.8
55
52 - - 82.6
54
52 - - 79.5
56
49 - - 41.3
57
49 - - 56.7
60
48 - - 76.7
58
48 - - 73.8
59
48 - - 77.0
61
47 - - 63.5
62
47 - - 92.1
63
46 - - 48.6
64
Ctp
46 - - 79.9
65
45 - - 51.4
66
45 - - 76.2
67
45 - - 83.0
68
44 - - 68.0
69
44 - - 86.6
70
43 - - 65.4
71
42 - - 62.3
72
38 - - 72.7
76
36 - - 74.7
74
36 - - 76.4
75
36 - - 92.6
73
36 - - 81.9
78
34 - - 81.2
77
34 - - 71.5
79
33 - - 72.8
80
31 - - 69.9
81
31 - - 84.4
82
30 - - 54.0
83
30 - - 73.8
84
28 - - 47.7
85
28 - - 73.0
86
28 - - 84.7
87
SoLute Carrier
28 - - 73.4
88
27 - - 76.5
89
26 - - 69.4
91
26 - - 82.6
92
26 - - 67.0
90
26 - - 84.8
93
26 - - 72.5
94
26 - - 73.0
96
25 - - 56.3
95
25 - - 77.5
97
25 - - 80.2
99
24 - - 89.7
102
24 - - 87.0
100
24 - - 62.0
101
SoLute Carrier
24 - - 84.0
98
24 - - 94.4
105
23 - - 74.2
103
23 - - 75.2
106
23 - - 75.3
104
23 - - 54.7
108
22 - - 18.6
109
22 - - 91.0
107
22 - - 73.1
112
Pet8
21 - - 83.6
111
21 - - 31.8
113
21 - - 73.3
110
21 - - 24.1
114
21 - - 54.3
119
20 - - 55.2
118
20 - - 67.4
116
20 - - 77.5
117
20 - - 24.2
115
20 - - 62.0
120
19 - - 69.4
121
19 - - 63.5
122
19 - - 82.0
123
Mitochondrial S-adenosylmethionine transporter
19 - - 79.0
124
18 - - 39.1
125
18 - - 80.1
126
18 - - 9.9
127
18 - - 80.0
128
17 - - 51.9
132
17 - - 69.2
129
17 - - 83.6
131
17 - - 75.1
133
Mitochondrial phosphate transporter
17 - - 44.6
130
17 - - 9.3
134
16 - - 74.8
136
16 - - 8.4
137
16 - - 18.0
135
16 - - 65.8
138
16 - - 56.2
142
15 - - 10.7
149
MC
15 - - 82.9
139
15 - - 84.5
148
15 - - 40.6
141
15 - - 81.7
144
15 - - 70.8
143
15 - - 5.5
147
Mitochondrial aspartate/glutamate transporter
15 - - 80.0
145
15 - - 45.9
146
15 - - 78.7
140
15 - - 46.0
150
15 - - 79.6
153
14 - - 9.0
154
14 - - 80.9
152
14 - - 71.9
151
14 - - 76.3
158
13 - - 39.2
157
13 - - 16.1
156
13 - - 42.0
155
13 - - 18.6
161
13 - - 20.3
160
13 - - 9.3
159
13 - - 44.3
162
13 - - 61.9
165
MC
12 - - 18.9
163
12 - - 62.3
166
MC
12 - - 17.8
164
12 - - 15.3
167
12 - - 89.5
170
11 - - 46.9
168
11 - - 38.7
171
11 - - 55.0
175
11 - - 80.7
174
11 - - 32.3
173
11 - - 43.8
169
Pet8
11 - - 71.1
172
11 - - 71.1
178
MC
10 - - 17.0
179
10 - - 56.2
177
10 - - 10.1
176
10 - - 1.9
180
10 - - 90.4
191
9 - - 23.1
184
AFU_orthologue AFUA_6G12900
9 - - 66.2
181
9 - - 42.2
192
MC
9 - - 8.9
183
9 - - 27.2
193
9 - - 19.6
186
9 - - 7.8
194
9 - - 77.3
185
9 - - 65.9
187
9 - - 13.8
188
9 - - 43.9
189
9 - - 78.2
182
9 - - 71.8
190
9 - - 76.8
199
8 - - 83.5
196
8 - - 58.7
198
8 - - 16.3
202
8 - - 80.6
200
8 - - 62.8
195
8 - - 32.0
203
8 - - 87.3
197
8 - - 1.2
201
8 - - 64.6
207
7 - - 64.4
209
SoLute Carrier
7 - - 55.5
204
7 - - 75.0
205
7 - - 1.2
212
7 - - 73.2
210
7 - - 35.4
211
7 - - 18.2
206
7 - - 54.8
208
7 - - 59.8
225
6 - - 74.8
222
6 - - 64.5
217
6 - - 15.7
224
6 - - 12.7
214
6 - - 39.4
226
6 - - 43.8
215
6 - - 10.3
213
6 - - 35.1
218
6 - - 9.4
221
6 - - 41.8
219
6 - - 10.1
220
6 - - 41.5
223
SoLute Carrier
6 - - 82.3
216
6 - - 14.9
232
5 - - 43.4
233
5 - - 37.9
236
5 - - 0.0
234
5 - - 72.4
227
5 - - 74.6
244
Rim2
5 - - 15.9
237
5 - - 14.3
235
Rim2 AFU_orthologue AFUA_3G06950
5 - - 53.3
246
5 - - 41.2
229
5 - - 18.7
247
5 - - 72.4
242
5 - - 13.3
243
5 - - 6.3
228
5 - - 36.3
238
5 - - 14.4
240
5 - - 7.7
230
5 - - 10.9
239
5 - - 13.4
245
5 - - 59.0
241
5 - - 7.1
231
5 - - 27.5
262
4 - - 68.8
252
4 - - 38.7
263
4 - - 74.6
253
4 - - 45.8
258
4 - - 3.2
248
4 - - 16.7
260
4 - - 32.7
264
SoLute Carrier
4 - - 48.8
259
4 - - 9.8
249
4 - - 8.0
265
4 - - 87.7
256
4 - - 8.7
261
4 - - 48.5
257
4 - - 9.2
254
4 - - 72.1
255
4 - - 2.6
250
4 - - 4.9
251
4 - - 9.1
272
3 - - 4.0
294
3 - - 62.2
278
3 - - 46.3
281
3 - - 6.2
279
Rim2
3 - - 10.7
293
3 - - 61.1
267
3 - - 48.3
280
3 - - 10.2
273
3 - - 0.0
288
3 - - 10.5
283
3 - - 3.4
270
3 - - 0.9
282
3 - - 4.2
285
3 - - 7.7
284
Rim2 AFU_orthologue AFUA_3G06950
3 - - 7.8
289
3 - - 10.4
290
3 - - 8.2
271
3 - - 11.4
268
3 - - 34.1
287
3 - - 3.8
274
3 - - 10.8
276
3 - - 6.2
269
3 - - 0.0
286
3 - - 10.1
275
3 - - 13.4
292
3 - - 43.9
291
3 - - 1.6
266
3 - - 33.0
277
3 - - 10.3
350
2 - - 40.8
311
2 - - 12.4
359
2 - - 0.0
395
2 - - 35.1
326
2 - - 0.8
335
2 - - 0.0
305
2 - - 15.4
319
2 - - 8.8
344
2 - - 13.5
336
2 - - 0.0
383
2 - - 0.0
365
2 - - 6.3
382
2 - - 4.2
351
2 - - 42.4
392
2 - - 32.2
329
2 - - 0.0
346
2 - - 37.2
310
2 - - 31.3
334
2 - - 5.0
362
2 - - 3.1
376
2 - - 9.1
371
2 - - 11.5
345
2 - - 34.0
318
2 - - 0.0
337
2 - - 11.7
400
2 - - 37.6
320
2 - - 0.0
385
2 - - 22.9
377
2 - - 0.0
338
2 - - 25.3
328
2 - - 0.4
397
2 - - 41.4
401
2 - - 15.8
297
2 - - 41.8
364
Mitochondrial
2 - - 0.0
295
2 - - 35.9
300
2 - - 16.6
296
SoLute Carrier
2 - - 41.0
352
2 - - 39.6
394
2 - - 30.0
374
2 - - 0.0
384
2 - - 7.7
343
2 - - 34.5
321
2 - - 0.4
306
2 - - 26.3
340
2 - - 20.1
391
2 - - 25.3
308
2 - - 30.5
301
2 - - 4.5
366
2 - - 0.0
349
2 - - 40.2
323
2 - - 11.1
330
2 - - 3.3
360
2 - - 0.0
353
2 - - 44.2
375
2 - - 12.8
387
2 - - 3.8
361
2 - - 9.9
307
2 - - 9.4
299
2 - - 36.9
315
2 - - 5.9
317
2 - - 11.9
367
2 - - 0.0
342
2 - - 32.6
341
2 - - 32.4
309
2 - - 34.2
399
2 - - 42.3
386
2 - - 0.0
372
2 - - 0.0
322
2 - - 8.4
354
2 - - 18.5
316
2 - - 4.3
314
AFU_orthologue AFUA_4G06390
2 - - 0.0
355
2 - - 17.5
302
2 - - 16.5
298
2 - - 38.3
339
2 - - 18.0
396
2 - - 35.7
356
2 - - 9.3
378
2 - - 8.6
325
2 - - 0.0
389
2 - - 27.0
381
2 - - 0.0
373
2 - - 0.0
333
2 - - 0.0
393
2 - - 31.6
303
2 - - 20.3
347
2 - - 38.3
363
2 - - 2.8
313
2 - - 0.0
357
2 - - 0.0
390
2 - - 29.4
358
2 - - 0.0
331
2 - - 0.0
348
2 - - 38.1
388
2 - - 43.9
324
2 - - 3.5
379
2 - - 0.0
312
2 - - 19.7
370
2 - - 0.9
380
2 - - 2.3
369
2 - - 0.0
332
2 - - 0.0
368
2 - - 0.5
327
2 - - 7.2
398
2 - - 37.6
304
2 - - 27.6
458
1 - - 0.0
495
1 - - 0.0
486
1 - - 0.0
558
AFU_orthologue AFUA_1G09980
1 - - 0.0
573
1 - - 0.0
506
1 - - 0.0
581
Eurofung
1 - - 0.0
468
1 - - 0.0
413
1 - - 0.0
432
1 - - 0.0
588
1 - - 0.0
542
1 - - 0.0
526
1 - - 0.0
490
1 - - 0.0
461
1 - - 0.0
425
1 - - 0.0
532
1 - - 0.0
412
1 - - 0.0
440
1 - - 0.0
467
1 - - 0.0
474
1 - - 0.0
563
1 - - 0.0
472
1 - - 0.0
600
1 - - 0.0
457
1 - - 0.0
505
1 - - 0.0
419
1 - - 0.0
406
1 - - 0.0
570
1 - - 0.0
408
1 - - 0.0
559
1 - - 0.0
580
1 - - 0.0
431
1 - - 0.0
523
1 - - 0.0
453
1 - - 0.0
595
1 - - 0.0
405
1 - - 0.0
507
1 - - 0.0
525
1 - - 0.0
427
1 - - 0.0
426
1 - - 0.0
498
1 - - 0.0
483
1 - - 0.0
533
1 - - 0.0
462
1 - - 0.0
414
1 - - 0.0
469
1 - - 0.0
543
1 - - 0.0
603
1 - - 0.0
565
1 - - 0.0
471
1 - - 0.0
562
AFU_orthologue AFUA_1G09980
1 - - 0.0
439
1 - - 0.0
407
1 - - 0.0
473
1 - - 0.0
560
1 - - 0.0
451
1 - - 0.0
578
1 - - 0.0
540
1 - - 0.0
571
1 - - 0.0
594
1 - - 0.0
430
1 - - 0.0
447
1 - - 0.0
415
1 - - 0.0
438
1 - - 0.0
493
1 - - 0.0
519
1 - - 0.0
556
1 - - 0.0
549
1 - - 0.0
583
1 - - 0.0
591
1 - - 0.0
442
1 - - 0.0
465
1 - - 0.0
479
1 - - 0.0
602
1 - - 0.0
576
1 - - 0.0
484
1 - - 0.0
561
1 - - 0.0
530
1 - - 0.0
470
1 - - 0.0
437
1 - - 0.0
527
1 - - 0.0
548
1 - - 0.0
460
1 - - 0.0
452
1 - - 0.0
579
1 - - 0.0
541
1 - - 0.0
416
1 - - 0.0
496
1 - - 0.0
605
1 - - 0.0
582
1 - - 0.0
557
1 - - 0.0
441
1 - - 0.0
590
1 - - 0.0
428
1 - - 0.0
500
1 - - 0.0
513
1 - - 0.0
429
1 - - 0.0
409
1 - - 0.0
489
1 - - 0.0
585
1 - - 0.0
518
1 - - 0.0
478
1 - - 0.0
531
1 - - 0.0
420
mitochondrial carrier; peroxisomal membrane protein
1 - - 0.0
577
mitochondrial carrier; phosphate carrier
1 - - 0.0
466
1 - - 0.0
512
1 - - 0.0
463
1 - - 0.0
517
1 - - 0.0
569
1 - - 0.0
536
1 - - 0.0
444
1 - - 0.0
508
1 - - 0.0
456
1 - - 0.0
545
1 - - 0.0
574
1 - - 0.0
566
1 - - 0.0
604
1 - - 0.0
477
1 - - 0.0
449
1 - - 0.0
501
1 - - 0.0
539
1 - - 0.0
520
1 - - 0.0
584
1 - - 0.0
554
1 - - 0.0
552
1 - - 0.0
481
1 - - 0.0
546
1 - - 0.0
537
1 - - 0.0
529
1 - - 0.0
421
1 - - 0.0
491
1 - - 0.0
597
1 - - 0.0
443
1 - - 0.0
509
1 - - 0.0
488
1 - - 0.0
436
1 - - 0.0
568
1 - - 0.0
476
1 - - 0.0
575
1 - - 0.0
511
1 - - 0.0
502
1 - - 0.0
553
1 - - 0.0
555
1 - - 0.0
423
1 - - 0.0
422
1 - - 0.0
593
1 - - 0.0
402
1 - - 0.0
464
1 - - 0.0
599
1 - - 0.0
587
1 - - 0.0
435
1 - - 0.0
596
1 - - 0.0
494
1 - - 0.0
487
1 - - 0.0
448
1 - - 0.0
547
1 - - 0.0
482
1 - - 0.0
499
1 - - 0.0
450
1 - - 0.0
528
mitochondrial carrier; phosphate carrier
1 - - 0.0
454
1 - - 0.0
586
1 - - 0.0
410
1 - - 0.0
480
1 - - 0.0
417
1 - - 0.0
534
1 - - 0.0
475
1 - - 0.0
515
1 - - 0.0
446
1 - - 0.0
510
1 - - 0.0
424
1 - - 0.0
434
1 - - 0.0
524
1 - - 0.0
598
1 - - 0.0
564
1 - - 0.0
503
1 - - 0.0
544
1 - - 0.0
522
1 - - 0.0
459
1 - - 0.0
404
1 - - 0.0
516
1 - - 0.0
455
1 - - 0.0
550
1 - - 0.0
592
1 - - 0.0
572
1 - - 0.0
418
1 - - 0.0
485
1 - - 0.0
535
1 - - 0.0
567
1 - - 0.0
445
1 - - 0.0
514
1 - - 0.0
589
1 - - 0.0
492
1 - - 0.0
538
1 - - 0.0
521
1 - - 0.0
433
1 - - 0.0
497
1 - - 0.0
411
1 - - 0.0
601
1 - - 0.0
551
1 - - 0.0
504
1 - - 0.0
403
1 - - 0.0