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CATH Superfamily 1.50.10.140

Glycoside hydrolase 144 (GH144)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Glycoside hydrolase 144 (GH144)

Glycoside hydrolase (GH) is a term for enzymes that catalyse the hydrolytic breakdown of the glycosidic linkages of glycosides, glycans, and glycoconjugates. GHs are distributed in almost all organisms.

This entry represents the GH144 family, which hydrolyses linear beta-1,2-glucan (a polysaccharide from Gram-negative bacteria, with important roles in infection and symbiosis). The structure of this enzyme has a large cavity appropriate for polysaccharide degradation and adopts an (alpha/alpha)6-fold slightly similar to that of GH family 15 and 8 enzymes PMID:28270506.

GO Diversity

Unique GO annotations
6 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
3019 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 11
Domain clusters (>95% seq id): 4
Domain clusters (>35% seq id): 1
Unique PDBs: 5
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 3
Function
Unique EC:
Unique GO: 6
Taxonomy
Unique Species: 3019