CATH Superfamily 1.20.58.390

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Neuronal nicotinic acetylcholine receptor subunit 3	1425		-	-	94.8
2	Putative gamma-aminobutyric acid receptor subunit alpha-5	1340	3D	5ojmE02	-	82.2
3	Glycine receptor alpha 2 subunit	997	3D	4x5tD02	-	81.0
4	Gamma-aminobutyric acid receptor subunit beta-2 isoform A	948	3D	4cofE02	-	59.2
133	Proton-gated ion channel	711	3D	6i08E02	-	98.7
5	Putative gamma-aminobutyric acid receptor subunit rho-2-like	675		-	-	95.8
6	Putative gamma-aminobutyric acid receptor subunit gamma-2	616		-	-	67.0
7	Neuronal acetylcholine receptor subunit alpha-7	556		-	-	79.4
8	Cholinergic receptor nicotinic beta 4 subunit	449	3D	2lm2A01	-	77.2
9	Cholinergic receptor nicotinic alpha 9 subunit	373		-	-	86.6
10	Nicotinic acetylcholine receptor subunit epsilon	343		-	-	86.5
11	neuronal acetylcholine receptor subunit alpha-7	282		-	-	88.7
12	Acetylcholine receptor subunit alpha-like	257		-	-	84.1
13	Putative acetylcholine receptor subunit alpha	248		-	-	55.3
14	Neuronal nicotinic acetylcholine receptor alpha4 subunit	240		-	-	75.4
15	Gamma-aminobutyric acid GABA-A	204		-	-	66.7
16	Putative acetylcholine receptor subunit alpha	184		-	-	81.2
17	Neuronal acetylcholine receptor subunit alpha-3	181		-	-	81.9
24	Glutamate-gated chloride channel alpha	179	3D	4tnwT02	-	82.3
19	Gamma-aminobutyric acid GABA	169		-	-	72.1
18	Glycine receptor subunit beta	169		-	-	38.1
20	5-hydroxytryptamine serotonin	156		-	-	85.8
21	glutamate-gated chloride channel isoform X12	155		-	-	40.8
22	Nicotinic acetylcholine receptor subunit alpha4	142		-	-	96.1
23	Nicotinic acetylcholine receptor subunit alpha6	139		-	-	76.1
25	Cholinergic receptor nicotinic beta 3 subunit	117		-	-	63.0
26	Cholinergic receptor nicotinic beta 1 subunit	115		-	-	69.7
27	Histamine-gated chloride channel subunit	113		-	-	69.0
28	Cholinergic receptor nicotinic beta 2 subunit	112		-	-	54.3
29	acetylcholine receptor subunit delta isoform X1	111		-	-	80.6
30	Acetylcholine receptor subunit alpha-L1	111		-	-	94.1
31	Cholinergic receptor nicotinic beta 1 subunit	109	3D	2bg9B02	-	55.1
32	gamma-aminobutyric acid receptor subunit epsilon	106		-	-	92.9
33	Gamma-aminobutyric acid receptor subunit beta	100		-	-	72.2
34	Cholinergic receptor nicotinic beta 4 subunit	100		-	-	81.0
35	Acetylcholine receptor subunit beta-like 1	98		-	-	93.3
36	Nicotinic acetylcholine receptor subunit gamma	96		-	-	81.0
37	Nicotinic acetylcholine receptor subunit alpha6	95		-	-	72.9
38	Acetylcholine receptor subunit beta-like 1	93		-	-	77.5
39	Ligand-Gated ion Channel	88		-	-	86.3
40	Gamma-aminobutyric acid receptor subunit beta-like	76		-	-	74.3
41	Neuronal acetylcholine receptor subunit alpha-5	75		-	-	78.1
42	5-hydroxytryptamine receptor 3C	70		-	-	71.9
43	AcetylCholine Receptor	69		-	-	97.9
44	neuronal acetylcholine receptor subunit alpha-9	67		-	-	95.2
45	neuronal acetylcholine receptor subunit alpha-10	61		-	-	60.3
46	AcetylCholine Receptor	60		-	-	89.4
47	Resistance to dieldrin, isoform H	59		-	-	52.8
48	Cholinergic receptor nicotinic epsilon subunit	57		-	-	85.8
49	AcetylCholine Receptor	54		-	-	81.7
50	glycine receptor subunit alpha-4	47		-	-	67.0
51	Cholinergic receptor, nicotinic, alpha 6	42		-	-	72.4
52	Cholinergic receptor nicotinic alpha 1 subunit	40	3D	2bg9D02	-	72.7
53	Neuronal acetylcholine receptor subunit alpha-9	38		-	-	77.1
55	Ligand-Gated ion Channel	37		-	-	81.3
56	5-hydroxytryptamine receptor 3B	37		-	-	74.7
54	Gamma-aminobutyric acid GABA-A	37		-	-	58.8
57	Resistance to dieldrin, isoform E	35		-	-	17.7
58	Nicotinic acetylcholine receptor alpha6, isoform D	33		-	-	64.8
59	Nicotinic acetylcholine receptor alpha6, isoform D	31		-	-	41.8
60	Ligand-Gated ion Channel	30		-	-	89.8
61	Ligand-Gated ion Channel	29		-	-	82.0
62	Neurotransmitter-gated ion-channel transmembrane region	29		-	-	31.8
63	AcetylCholine Receptor	28		-	-	68.5
64	Neuronal acetylcholine receptor subunit alpha-7	27		-	-	78.9
65	GABA-gated ion channel	25		-	-	73.5
66	Acetylcholine receptor subunit alpha-type unc-63	25		-	-	38.1
67	Glycine receptor subunit alpha-2	24		-	-	93.4
68	zinc-activated ligand-gated ion channel	23		-	-	67.3
69	Ligand-Gated ion Channel	23		-	-	59.2
70	Glycine receptor beta	22		-	-	61.4
71	Ligand-Gated ion Channel	20		-	-	54.8
72	Uncharacterized protein	20		-	-	75.1
73	Neuronal acetylcholine receptor subunit alpha-9-II	20		-	-	88.9
74	Gamma-aminobutyric acid type A receptor gamma2 subunit	19		-	-	74.0
75	Neuronal acetylcholine receptor subunit alpha-9-II	19		-	-	97.6
76	Glutamate-gated chloride channel, putative	19		-	-	89.0
78	AcetylCholine Receptor	18		-	-	84.9
77	Ligand-gated ion channel 50	18		-	-	15.4
79	Cholinergic receptor, nicotinic, epsilon	17		-	-	45.1
80	5-hydroxytryptamine serotonin	16		-	-	77.7
81	Proton-gated ion channel subunit pbo-5	16		-	-	68.9
82	Glutamate-gated ChLoride channel	15		-	-	76.9
85	Gamma-aminobutyric acid type A receptor pi subunit	14		-	-	6.6
86	Acetylcholine receptor subunit beta-type acr-2	14		-	-	68.0
84	Glutamate-gated chloride channel subunit beta	14		-	-	75.6
83	Ligand-Gated ion Channel	14		-	-	57.9
87	GABA-gated ion channel	13		-	-	38.8
88	Uncharacterized protein	13		-	-	83.3
89	Ligand-Gated ion Channel	12		-	-	45.5
91	Glycine receptor, beta a	12		-	-	24.4
92	Nicotinic acetylcholine receptor subunit alpha10	12		-	-	97.1
90	Ligand-Gated ion Channel	12		-	-	80.5
93	Uncharacterized protein	12		-	-	90.9
96	Ligand-Gated ion Channel	11		-	-	72.2
94	Ligand-Gated ion Channel	11		-	-	25.6
95	Ionotropic GABA receptor subunit UNC-49B.3	11		-	-	75.5
98	Predicted protein	11		-	-	84.7
97	Gamma-aminobutyric acid GABA	11		-	-	43.3
101	Uncharacterized protein	10		-	-	75.4
99	Cholinergic receptor, nicotinic, epsilon	10		-	-	96.4
100	Predicted protein	10		-	-	85.5
108	Uncharacterized protein	9		-	-	42.0
105	AcetylCholine Receptor	9		-	-	41.3
109	AcetylCholine Receptor	9		-	-	52.6
106	ACHA7	9		-	-	16.5
107	AcetylCholine Receptor	9		-	-	9.5
102	Glycine receptor subunit beta-type 4	9		-	-	30.2
104	AcetylCholine Receptor	9		-	-	21.5
103	Si:ch211-256e16.10	9		-	-	71.6
112	Acetylcholine receptor subunit alpha-type unc-63	8		-	-	6.5
111	AcetylCholine Receptor	8		-	-	22.2
113	Ionotropic GABA receptor subunit UNC-49Cshort	8		-	-	69.1
110	Uncharacterized protein	8		-	-	79.6
114	Uncharacterized protein	8		-	-	85.4
116	Gamma-aminobutyric acid type A receptor beta2 subunit	7		-	-	32.2
117	Uncharacterized protein	7		-	-	77.1
124	Protein CBG26995	7		-	-	67.1
120	5-hydroxytryptamine receptor 3A	7		-	-	46.8
121	Uncharacterized protein	7		-	-	93.0
119	AcetylCholine Receptor	7		-	-	9.7
115	GABA/Glycine Receptor family See gbr	7		-	-	26.6
122	Uncharacterized protein	7		-	-	49.4
118	GABA-gated ion channel	7		-	-	79.2
123	Uncharacterized protein	7		-	-	69.4
127	AcetylCholine Receptor	6		-	-	19.5
128	Neuronal acetylcholine receptor subunit eat-2	6		-	-	75.3
132	Uncharacterized protein	6		-	-	89.7
129	AcetylCholine Receptor	6		-	-	9.8
131	Predicted protein	6		-	-	79.4
130	Si:ch211-256e16.7	6		-	-	95.0
125	Acetylcholine-gated ion channel acc-4	6		-	-	9.0
126	Ligand-Gated ion Channel	6		-	-	15.1
136	Ligand-Gated ion Channel	5		-	-	55.6
137	Predicted protein	5		-	-	72.7
142	Uncharacterized protein	5		-	-	55.6
139	AcetylCholine Receptor	5		-	-	23.7
135	Ligand-Gated ion Channel	5		-	-	37.8
145	Predicted protein	5		-	-	71.8
141	Predicted protein	5		-	-	86.2
144	Protein CBR-ACR-25	5		-	-	89.8
138	Predicted protein	5		-	-	82.8
140	Neuronal acetylcholine receptor subunit eat-2	5		-	-	59.6
143	5-hydroxytryptamine receptor 3D	5		-	-	45.1
134	Ligand-Gated ion Channel	5		-	-	12.9
153	Acetylcholine receptor subunit alpha-type acr-7	4		-	-	17.8
155	Nicotinic acetylcholine receptor subunit	4		-	-	10.0
154	CBN-LEV-8 protein	4		-	-	5.6
158	Nicotinic acetylcholine receptor subunit	4		-	-	60.9
147	Uncharacterized protein	4		-	-	61.4
149	Uncharacterized protein	4		-	-	73.5
152	GABA/Glycine Receptor family See gbr	4		-	-	55.7
148	Transmembrane ion channel	4		-	-	65.6
157	Ionotropic GABA receptor subunit UNC-49C	4		-	-	18.8
146	Uncharacterized protein	4		-	-	37.4
160	5-hydroxytryptamine serotonin	4		-	-	41.6
151	AcetylCholine Receptor	4		-	-	23.6
156	Uncharacterized protein	4		-	-	28.9
150	Neurotransmitter-gated ion-channel ligand binding domain protein	4		-	-	15.6
159	Acetylcholine receptor subunit alpha-type acr-16	4		-	-	69.5
180	Uncharacterized protein	3		-	-	47.2
170	Predicted protein	3		-	-	42.4
175	Predicted protein	3		-	-	70.1
165	AGAP007707-PA	3		-	-	4.7
168	Cholinergic receptor nicotinic beta 1 subunit	3		-	-	4.3
178	Predicted protein	3		-	-	75.8
161	Uncharacterized protein	3		-	-	50.4
174	Nicotinic acetylcholine receptor subunit	3		-	-	40.0
179	Predicted protein	3		-	-	55.2
164	Predicted protein	3		-	-	79.1
177	Uncharacterized protein	3		-	-	47.0
167	Nicotinic acetylcholine receptor subunit	3		-	-	3.1
163	Acetylcholine receptor subunit alpha	3		-	-	44.7
173	Predicted protein	3		-	-	71.6
171	Glycine receptor alpha 1 variant, putative	3		-	-	71.9
176	Predicted protein	3		-	-	72.8
162	Uncharacterized protein	3		-	-	63.9
169	Uncharacterized protein	3		-	-	33.7
172	Uncharacterized protein	3		-	-	59.4
166	Uncharacterized protein	3		-	-	41.6
191	Predicted protein	2		-	-	39.7
187	Ligand-Gated ion Channel	2		-	-	36.8
212	Nicotinic acetylcholine receptor subunit	2		-	-	0.0
232	Uncharacterized protein	2		-	-	27.8
225	Predicted protein	2		-	-	39.0
207	Cholinergic receptor nicotinic delta subunit	2		-	-	40.9
198	Transmembrane ion channel	2		-	-	0.0
202	Transmembrane ion channel	2		-	-	8.5
184	Uncharacterized protein	2		-	-	32.5
181	Predicted protein	2		-	-	7.3
229	Uncharacterized protein	2		-	-	41.1
222	Uncharacterized protein	2		-	-	30.9
217	Uncharacterized protein	2		-	-	27.4
209	Cholinergic receptor nicotinic alpha 10 subunit	2		-	-	43.5
210	Nicotinic acetylcholine receptor subunit	2		-	-	0.0
213	Acr-19	2		-	-	0.0
200	Uncharacterized protein	2		-	-	7.9
224	Uncharacterized protein	2		-	-	34.8
192	Predicted protein	2		-	-	43.2
199	Ligand-gated ion channel	2		-	-	4.8
195	Gamma-aminobutyric acid type A receptor rho3 subunit gene/pseudogene	2		-	-	43.1
188	Uncharacterized protein	2		-	-	35.6
183	Uncharacterized protein	2		-	-	34.2
203	Predicted protein	2		-	-	1.3
204	Neurotransmitter-gated ion-channel ligand binding domain protein	2		-	-	12.8
228	Uncharacterized protein	2		-	-	39.2
211	Uncharacterized protein	2		-	-	5.4
218	Uncharacterized protein	2		-	-	35.6
193	Predicted protein	2		-	-	41.8
189	Predicted protein	2		-	-	33.7
221	AcetylCholine Receptor	2		-	-	10.2
205	Uncharacterized protein	2		-	-	0.0
227	Glycine receptor alpha chain, putative	2		-	-	40.9
182	Predicted protein	2		-	-	14.3
230	Uncharacterized protein	2		-	-	51.8
214	Uncharacterized protein	2		-	-	6.6
186	Gamma-aminobutyric acid GABA	2		-	-	32.6
219	Gamma-aminobutyric acid GABA	2		-	-	40.5
196	Uncharacterized protein	2		-	-	43.3
206	Uncharacterized protein	2		-	-	31.3
194	Uncharacterized protein	2		-	-	38.8
220	Uncharacterized protein	2		-	-	2.0
226	Predicted protein	2		-	-	40.1
197	Glutamate-gated chloride channel, putative	2		-	-	49.8
215	Nicotinic acetylcholine receptor subunit	2		-	-	0.0
208	Uncharacterized protein	2		-	-	38.2
201	Gamma-aminobutyric acid type A receptor pi subunit	2		-	-	9.2
190	Uncharacterized protein	2		-	-	42.0
231	Uncharacterized protein	2		-	-	40.7
223	Predicted protein	2		-	-	38.6
216	Nicotinic acetylcholine receptor subunit	2		-	-	0.0
185	Uncharacterized protein	2		-	-	23.3
311	Uncharacterized protein	1		-	-	0.0
285	Uncharacterized protein	1		-	-	0.0
246	Uncharacterized protein	1		-	-	0.0
308	Protein CBR-ACR-3	1		-	-	0.0
301	AcetylCholine Receptor	1		-	-	0.0
272	Uncharacterized protein	1		-	-	0.0
294	Uncharacterized protein	1		-	-	0.0
323	Ligand-Gated ion Channel	1		-	-	0.0
262	Uncharacterized protein	1		-	-	0.0
330	Uncharacterized protein	1		-	-	0.0
278	Uncharacterized protein	1		-	-	0.0
257	Uncharacterized protein	1		-	-	0.0
307	Uncharacterized protein	1		-	-	0.0
326	Uncharacterized protein	1		-	-	0.0
299	Uncharacterized protein	1		-	-	0.0
315	Uncharacterized protein	1		-	-	0.0
305	Uncharacterized protein	1		-	-	0.0
281	Uncharacterized protein	1		-	-	0.0
317	Uncharacterized protein	1		-	-	0.0
284	Uncharacterized protein	1		-	-	0.0
247	Uncharacterized protein	1		-	-	0.0
289	Cholinergic receptor, nicotinic, alpha polypeptide 9	1		-	-	0.0
319	Uncharacterized protein	1		-	-	0.0
290	Uncharacterized protein	1		-	-	0.0
252	Uncharacterized protein	1		-	-	0.0
271	Uncharacterized protein	1		-	-	0.0
242	AGAP009493-PA	1		-	-	0.0
309	Uncharacterized protein	1		-	-	0.0
254	Uncharacterized protein	1		-	-	0.0
329	Uncharacterized protein	1		-	-	0.0
279	Predicted protein	1		-	-	0.0
263	Glycine receptor alpha 1 variant, putative	1		-	-	0.0
293	Uncharacterized protein	1		-	-	0.0
322	Uncharacterized protein	1		-	-	0.0
310	Uncharacterized protein	1		-	-	0.0
267	Uncharacterized protein	1		-	-	0.0
233	Protein CBR-LGC-39	1		-	-	0.0
316	Uncharacterized protein	1		-	-	0.0
280	Uncharacterized protein	1		-	-	0.0
273	Uncharacterized protein	1		-	-	0.0
314	Uncharacterized protein	1		-	-	0.0
334	Uncharacterized protein	1		-	-	0.0
302	Uncharacterized protein	1		-	-	0.0
298	Hypothetical protein LOC100135106	1		-	-	0.0
243	Uncharacterized protein	1		-	-	0.0
268	Predicted protein	1		-	-	0.0
238	Gamma-aminobutyric acid type A receptor alpha6 subunit	1		-	-	0.0
253	Uncharacterized protein	1		-	-	0.0
258	Uncharacterized protein	1		-	-	0.0
318	Uncharacterized protein	1		-	-	0.0
248	Uncharacterized protein	1		-	-	0.0
325	Uncharacterized protein	1		-	-	0.0
236	Uncharacterized protein	1		-	-	0.0
234	Uncharacterized protein	1		-	-	0.0
288	Uncharacterized protein	1		-	-	0.0
260	Glycine receptor alpha 4	1		-	-	0.0
287	Predicted protein	1		-	-	0.0
333	Uncharacterized protein	1		-	-	0.0
264	Glutamate-gated chloride channel, putative	1		-	-	0.0
255	Uncharacterized protein	1		-	-	0.0
274	Uncharacterized protein	1		-	-	0.0
250	Uncharacterized protein	1		-	-	0.0
303	Uncharacterized protein	1		-	-	0.0
276	SD09326p	1		-	-	0.0
259	Uncharacterized protein	1		-	-	0.0
320	Glycine receptor alpha 4b subunit	1		-	-	0.0
249	Uncharacterized protein	1		-	-	0.0
240	Uncharacterized protein	1		-	-	0.0
328	Uncharacterized protein	1		-	-	0.0
239	Uncharacterized protein	1		-	-	0.0
269	Zinc activated ion channel	1		-	-	0.0
313	Uncharacterized protein	1		-	-	0.0
297	Uncharacterized protein	1		-	-	0.0
283	Si:dkey-49c17.4	1		-	-	0.0
331	Uncharacterized protein	1		-	-	0.0
324	Uncharacterized protein	1		-	-	0.0
244	Uncharacterized protein	1		-	-	0.0
295	Cholinergic receptor nicotinic gamma subunit	1		-	-	0.0
312	Protein CBG01449	1		-	-	0.0
237	Uncharacterized protein	1		-	-	0.0
300	Uncharacterized protein	1		-	-	0.0
286	GABA-A receptor epsilon subunit	1		-	-	0.0
235	Uncharacterized protein	1		-	-	0.0
296	Uncharacterized protein	1		-	-	0.0
265	Uncharacterized protein	1		-	-	0.0
275	Uncharacterized protein	1		-	-	0.0
251	Uncharacterized protein	1		-	-	0.0
256	Uncharacterized protein	1		-	-	0.0
245	Si:ch211-256e16.4	1		-	-	0.0
332	Uncharacterized protein	1		-	-	0.0
292	Uncharacterized protein	1		-	-	0.0
291	Uncharacterized protein	1		-	-	0.0
241	Uncharacterized protein	1		-	-	0.0
327	Uncharacterized protein	1		-	-	0.0
270	Uncharacterized protein	1		-	-	0.0
266	Uncharacterized protein	1		-	-	0.0
261	Uncharacterized protein	1		-	-	0.0
321	Uncharacterized protein	1		-	-	0.0
282	Uncharacterized protein	1		-	-	0.0
277	Uncharacterized protein	1		-	-	0.0
304	Uncharacterized protein	1		-	-	0.0
306	Uncharacterized protein	1		-	-	0.0