View in Gene3D

CATH Superfamily 1.20.1640.10

Multidrug efflux transporter AcrB transmembrane domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Multidrug efflux transporter AcrB transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Efflux pump membrane transporter
1209
3D
 5yilC01 - 97.9
2
Efflux pump membrane transporter
651
3D
 5yilC05 - 92.4
3
protein patched homolog 1
425 - - 79.5
4
Protein translocase subunit SecD
405 - - 96.3
5
Multidrug resistance protein MdtC
359 - - 64.4
6
Protein-export membrane protein SecF
357 - - 78.1
7
Protein patched homolog 1
353 - - 70.3
8
NPC intracellular cholesterol transporter 1
255 - - 92.4
9
Dispatched homolog 1
Drosophila
224 - - 64.5
10
NPC intracellular cholesterol transporter 1
209 - - 87.2
11
Dispatched RND transporter family member 1
205 - - 76.8
12
Cation efflux system protein CusA
149 - - 19.8
13
PaTched Related family
119 - - 98.5
14
Protein translocase subunit SecD
115 - - 65.2
15
Dispatched RND transporter family member 3
107 - - 25.6
16
Patched domain-containing protein 1
106 - - 25.1
17
Patched domain-containing protein 1
104 - - 24.2
18
Transmembrane transport protein MmpL10
92 - - 86.4
19
Patched 2
74 - - 44.2
20
Transmembrane transport protein MmpL10
54 - - 92.1
21
Cation efflux system protein CusA
53 - - 22.0
22
Dispatched RND transporter family member 3
52 - - 39.1
23
Protein-export membrane protein SecF
51 - - 63.8
24
Multifunctional fusion protein
47 - - 89.7
25
Protein-export membrane protein SecF
41 - - 42.5
26
Dispatched RND transporter family member 2
33 - - 60.1
27
Blast:Protein patched
28 - - 83.6
28
PaTched Related family
27 - - 79.0
29
Putative Patched sphingolipid transporter
26 - - 73.6
30
Patched homolog
Drosophila
24 - - 7.2
31
PaTChed family
23 - - 79.4
32
MMPL family transporter
22 - - 14.2
33
MMPL family transporter
22 - - 15.4
34
Protein-export membrane protein SecF
22 - - 52.8
35
PaTched Related family
21 - - 77.1
36
PaTched Related family
20 - - 78.3
37
Protein-export membrane protein SecF
17 - - 30.1
39
Protein-export membrane protein SecF
16 - - 9.1
38
Blast:Protein patched
16 - - 47.0
40
Export membrane protein
15 - - 19.1
41
Multidrug transporter AcrB
14 - - 22.2
42
Export membrane protein
13 - - 14.7
43
Protein CBR-PTC-3
12 - - 33.0
44
Multifunctional fusion protein
12 - - 51.9
45
Multifunctional fusion protein
11 - - 20.8
48
protein patched homolog 1 isoform X2
10 - - 67.0
46
Multidrug transporter AcrB
10 - - 17.1
49
Transmembrane transport protein MmpL11
10 - - 7.7
50
Protein CBR-CHE-14
10 - - 14.0
47
PaTched Related family
10 - - 47.1
51
PaTched Related family
9 - - 14.7
55
Protein-export membrane protein SecF
9 - - 78.7
52
Transmembrane transport protein MmpL11
9 - - 0.0
53
PaTched Related family
9 - - 13.5
56
PaTched Related family
9 - - 13.3
54
Protein CBR-NCR-1
9 - - 18.6
58
PaTched Related family
8 - - 20.3
57
MMPL domain-containing drug exporter
8 - - 9.3
59
PaTched Related family
8 - - 13.3
61
Protein patched homolog 1
7 - - 14.6
64
PaTched Related family
7 - - 14.7
60
Resistance-Nodulation-cell Division
RND
7 - - 15.3
65
PaTched Related family
7 - - 14.3
63
PaTched Related family
7 - - 15.3
66
Protein-export membrane protein SecF
7 - - 3.0
62
Patched-related protein 9
7 - - 12.0
67
Transmembrane transport protein mmpL13b
7 - - 11.7
71
Patched-related protein 9
6 - - 11.5
78
Protein CBG18375
6 - - 11.1
74
PaTched Related family
6 - - 11.6
68
RND multidrug efflux transporter
6 - - 0.0
69
Transporter, AcrB/D/F family
6 - - 0.0
75
Niemann-Pick C1 protein
6 - - 15.9
76
NPC intracellular cholesterol transporter 1 homolog 1
6 - - 14.7
77
Transmembrane transport protein MmpL3
6 - - 6.7
72
Hopanoid biosynthesis associated RND transporter like protein HpnN
6 - - 19.7
73
PaTched Related family
6 - - 14.5
70
GM10585
6 - - 15.1
85
Transmembrane transport protein mmpL13a
5 - - 0.8
80
Putative multidrug resistance protein
5 - - 26.5
82
Protein patched
5 - - 3.8
81
Transporter, AcrB/D/F family
5 - - 0.0
84
PaTched Related family
5 - - 8.0
79
Putative multidrug resistance protein
5 - - 25.8
83
Trehalose monomycolate exporter MmpL3
5 - - 0.0
86
Bifunctional preprotein translocase subunit SecD/SecF
4 - - 1.2
87
Bifunctional preprotein translocase subunit SecD/SecF
4 - - 1.6
88
Hopanoid biosynthesis associated RND transporter like protein HpnN
4 - - 17.5
89
Protein translocase subunit SecD
3 - - 10.8
91
Acyltrehalose exporter MmpL10
3 - - 0.0
92
Patched domain-containing protein 3
3 - - 10.0
94
Multifunctional fusion protein
3 - - 3.0
90
Predicted protein
3 - - 9.4
93
Protein-export membrane protein SecF
3 - - 11.7
101
2 - - 0.0
96
2 - - 3.8
99
2 - - 7.3
95
2 - - 0.6
98
2 - - 5.5
102
2 - - 0.0
100
2 - - 8.7
103
2 - - 8.1
97
2 - - 10.1
112
1 - - 0.0
108
1 - - 0.0
105
1 - - 0.0
111
1 - - 0.0
109
1 - - 0.0
106
1 - - 0.0
107
1 - - 0.0
110
1 - - 0.0
104
1 - - 0.0