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CATH Superfamily 1.20.120.350

Voltage-gated potassium channels. Chain C

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Voltage-gated potassium channels. Chain C
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Voltage-dependent L-type calcium channel subunit alpha
2508 - - 94.5
2
Sodium channel protein
1944 - - 89.2
3
Voltage-dependent sodium channel
1837 - - 86.7
4
Sodium channel protein
1722
3D
 5ek0D01 - 86.1
5
Sodium channel protein
1329 - - 87.9
6
Voltage-dependent L-type calcium channel subunit alpha
1212 - - 90.1
7
Voltage-dependent T-type calcium channel subunit alpha
1078 - - 89.1
8
Voltage-dependent T-type calcium channel subunit alpha
1061 - - 91.1
9
Voltage-dependent T-type calcium channel subunit alpha
1054 - - 97.0
10
Voltage-dependent L-type calcium channel subunit alpha
1013 - - 84.7
11
Voltage-dependent N-type calcium channel subunit alpha
959 - - 88.3
12
Voltage-dependent T-type calcium channel subunit alpha
897 - - 91.7
13
Voltage-dependent N-type calcium channel subunit alpha
887 - - 90.0
14
Potassium channel, voltage-gated Shaw-related subfamily C, member 4
718 - - 82.6
15
Voltage-dependent N-type calcium channel subunit alpha
700 - - 93.2
16
Potassium voltage-gated channel subfamily D member 3
675 - - 82.8
17
potassium voltage-gated channel subfamily KQT member 1
540 - - 91.4
18
Potassium voltage-gated channel subfamily B member
422 - - 81.4
19
Sodium channel protein
399 - - 86.8
20
Voltage-dependent L-type calcium channel subunit alpha
354 - - 74.5
21
Potassium voltage-gated channel subfamily A member 3
335 - - 69.1
22
Sodium channel protein
333 - - 73.6
23
Sodium channel protein
329 - - 74.7
24
Potassium voltage-gated channel subfamily G member 1
300 - - 77.8
25
Potassium voltage-gated channel subfamily A member 2
296
3D
 3lutB02 - 73.1
26
Sodium channel protein
287 - - 75.7
27
Voltage-dependent L-type calcium channel subunit alpha
285 - - 58.0
28
Potassium voltage-gated channel subfamily a member
273 - - 87.8
29
Potassium voltage-gated channel subfamily S member 2
217 - - 82.3
30
sodium leak channel non-selective protein
177 - - 97.1
31
Two pore calcium channel protein 1
176 - - 72.4
32
Sodium leak channel non-selective protein
145 - - 78.6
33
potassium voltage-gated channel subfamily A member 10
138 - - 70.7
35
Calcium-activated potassium channel slowpoke
123 - - 57.0
34
Sodium leak channel non-selective protein
123 - - 69.4
36
Voltage-dependent sodium channel SCN10A
118 - - 84.9
37
Voltage-dependent L-type calcium channel subunit alpha
117 - - 71.8
38
Sodium leak channel non-selective protein
115 - - 53.0
39
Sodium channel protein
112 - - 80.4
40
Voltage-dependent L-type calcium channel subunit alpha
109 - - 85.5
41
Transmembrane protein 266
99 - - 39.5
42
Potassium voltage-gated channel subfamily V member 2
99 - - 85.1
43
Voltage-dependent L-type calcium channel subunit alpha
98 - - 74.7
45
Potassium voltage-gated channel subfamily S member 3
97 - - 73.6
44
Potassium voltage-gated channel subfamily V member 1
97 - - 64.8
46
Potassium voltage-gated channel subfamily F member 1
94 - - 60.6
47
Uncharacterized protein, isoform C
94 - - 74.6
48
Potassium voltage-gated channel modifier subfamily G member 3
90 - - 57.8
49
Sodium channel protein
81 - - 70.5
50
Solute carrier family 9 member C1
80 - - 96.2
51
Voltage-dependent L-type calcium channel subunit alpha
78 - - 53.4
52
polycystic kidney disease 2-like 1 protein isoform X1
77 - - 76.6
53
Sodium channel protein
75 - - 70.8
54
voltage-gated hydrogen channel 1
72 - - 77.2
55
Two pore calcium channel protein 1
70 - - 95.4
56
Two pore segment channel 2
69 - - 46.2
58
Sodium channel protein
68 - - 78.9
57
Sodium channel protein
68 - - 58.2
59
Sodium channel protein
67 - - 93.0
60
Voltage-dependent L-type calcium channel subunit alpha
63 - - 42.0
61
Potassium voltage-gated channel subfamily C member 2
61 - - 59.1
122
Ion transport protein
61
3D
 4mw8D01 - 79.0
62
Voltage-dependent L-type calcium channel subunit alpha
61 - - 62.9
64
Voltage-dependent L-type calcium channel subunit alpha
59 - - 71.2
63
Calcium channel subunit Cch1
59 - - 91.2
65
Sodium channel protein
58 - - 81.9
66
Sodium channel protein
56 - - 90.4
67
Transmembrane phosphatase with tensin homology
53 - - 69.7
68
Sodium channel protein
52 - - 97.3
69
Voltage-dependent L-type calcium channel subunit alpha
51 - - 62.2
70
K+ channel tetramerization domain protein
47 - - 88.2
71
Potassium voltage-gated channel protein shk-1
43 - - 90.6
72
Voltage-dependent T-type calcium channel subunit alpha
42 - - 90.6
73
Two pore segment channel 2
42 - - 65.2
74
SHaW family of potassium channels
41 - - 95.2
75
Sodium channel protein
41 - - 90.9
76
Ion transporter, putative
39 - - 79.0
77
Voltage-dependent L-type calcium channel subunit alpha
37 - - 40.0
78
Cation channel sperm associated 1
32 - - 89.1
79
Calcium channel subunit Cch1
29 - - 94.2
80
Polycystic kidney disease 2
27 - - 57.3
82
Uncharacterized protein
26 - - 99.0
81
Predicted protein
26 - - 97.6
85
potassium voltage-gated channel subfamily G member 2
23 - - 30.4
84
Cation channel sperm associated 2
23 - - 69.0
83
Sodium channel protein
23 - - 60.2
86
Potassium voltage-gated channel subfamily KQT member 1
22 - - 27.2
87
Uncharacterized protein
22 - - 97.2
89
Four domain-type voltage-gated ion channel alpha-1 subunit
21 - - 9.6
90
Voltage-dependent L-type calcium channel subunit alpha
21 - - 74.6
88
Protein CBG09661
21 - - 47.6
91
Predicted protein
20 - - 98.3
92
Sodium channel protein
19 - - 60.8
93
Uncharacterized protein
19 - - 95.1
94
Voltage-dependent P/Q-type calcium channel subunit alpha
18 - - 56.1
95
Voltage-gated Ca2+ channel, alpha subunit
17 - - 96.7
96
Sodium channel protein
16 - - 13.6
98
Calcium channel subunit Cch1
16 - - 85.5
97
Calcium channel subunit Cch1
16 - - 72.6
99
Cation channel sperm associated 4
15 - - 26.6
100
Voltage-gated Ion Channel
VIC
15 - - 14.7
101
Voltage-gated Ion Channel
VIC
14 - - 22.0
102
Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence
14 - - 17.9
103
Voltage-gated Ion Channel
VIC
12 - - 20.0
104
Unplaced genomic scaffold supercont1.219, whole genome shotgun sequence
11 - - 11.8
105
CRE-KVS-1 protein
9 - - 9.7
108
Sodium channel, voltage-gated, type VIII, alpha subunit b
8 - - 81.9
109
Calcium channel subunit Cch1
8 - - 14.1
106
Potassium voltage-gated channel, Shab-related subfamily, member 2
8 - - 30.2
107
Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence
8 - - 12.8
110
Sodium channel protein
8 - - 73.9
112
Voltage-gated Ca2+ channel, alpha subunit
7 - - 88.0
111
Cation channel sperm-associated protein 3
7 - - 40.2
113
Uncharacterized protein
7 - - 92.1
116
pH-gated potassium channel KcsA
6 - - 0.0
117
Predicted protein
6 - - 90.8
120
Voltage-dependent L-type calcium channel subunit alpha
6 - - 74.8
119
Calcium channel, voltage-dependent, T type, alpha 1H subunit a
6 - - 75.3
115
Uncharacterized protein
6 - - 93.5
118
Voltage-dependent calcium channel subunit, putative
6 - - 39.7
114
Potassium voltage-gated channel modifier subfamily V member 1
6 - - 79.7
127
Voltage-dependent L-type calcium channel subunit alpha
5 - - 59.6
128
Uncharacterized protein
5 - - 82.9
129
Uncharacterized protein
5 - - 89.3
124
Four domain-type voltage-gated ion channel alpha-1 subunit
5 - - 3.9
121
Potassium channel
5 - - 44.9
130
Uncharacterized protein
5 - - 83.1
125
Protein CBR-SHW-1
5 - - 8.6
126
Related to CCH1-Calcium channel
Alpha subunit
5 - - 14.3
123
Potassium channel subunit
5 - - 7.8
136
Potassium voltage-gated channel, subfamily G, member 4b
4 - - 9.0
137
Calcium channel protein, putative
4 - - 11.7
142
4 - - 32.6
132
Potassium voltage-gated channel, subfamily G, member 4a
4 - - 39.1
139
Putative calcium channel protein
4 - - 9.2
135
Uncharacterized protein
4 - - 74.7
131
Sodium channel protein
4 - - 15.6
141
Voltage-gated Ca2+ channel, alpha subunit
4 - - 30.4
138
Putative calcium channel protein
4 - - 9.8
140
4 - - 0.0
133
cation channel sperm-associated protein 2-like
4 - - 73.5
134
Uncharacterized protein
4 - - 66.7
153
3 - - 34.7
155
3 - - 36.1
154
3 - - 30.7
147
3 - - 25.2
149
3 - - 5.7
145
3 - - 11.7
152
3 - - 0.0
148
Sodium/hydrogen exchanger 10-like Protein
3 - - 78.2
157
3 - - 82.9
146
3 - - 23.6
144
3 - - 8.7
151
3 - - 9.6
156
3 - - 0.0
150
3 - - 11.1
143
3 - - 0.0
180
2 - - 0.0
191
2 - - 0.0
187
2 - - 1.0
170
2 - - 0.0
207
2 - - 40.1
175
2 - - 7.1
198
2 - - 42.1
202
2 - - 0.0
184
2 - - 0.0
181
2 - - 7.5
158
2 - - 0.0
165
2 - - 12.3
209
2 - - 41.6
168
2 - - 0.0
178
2 - - 8.3
200
2 - - 0.9
161
2 - - 0.0
192
2 - - 6.3
199
2 - - 0.0
195
2 - - 27.3
174
2 - - 0.0
188
2 - - 8.9
183
2 - - 0.0
203
2 - - 2.0
204
2 - - 0.0
179
2 - - 0.0
164
2 - - 29.8
160
2 - - 8.4
193
2 - - 29.2
189
2 - - 34.3
177
2 - - 0.0
205
2 - - 0.0
182
2 - - 0.0
167
2 - - 37.0
163
2 - - 42.6
186
2 - - 0.0
173
2 - - 0.0
196
2 - - 38.7
206
2 - - 39.9
194
2 - - 12.7
171
2 - - 0.0
197
2 - - 40.7
176
2 - - 4.0
208
2 - - 46.1
159
2 - - 9.8
162
2 - - 46.0
201
2 - - 8.4
169
2 - - 39.4
190
2 - - 43.9
172
2 - - 0.0
166
2 - - 33.1
185
2 - - 0.0
246
1 - - 0.0
272
1 - - 0.0
262
1 - - 0.0
212
1 - - 0.0
232
1 - - 0.0
225
1 - - 0.0
257
1 - - 0.0
229
1 - - 0.0
222
1 - - 0.0
217
1 - - 0.0
247
1 - - 0.0
210
1 - - 0.0
252
1 - - 0.0
271
1 - - 0.0
242
1 - - 0.0
254
1 - - 0.0
213
1 - - 0.0
224
1 - - 0.0
263
1 - - 0.0
267
1 - - 0.0
233
1 - - 0.0
273
1 - - 0.0
243
1 - - 0.0
228
1 - - 0.0
268
1 - - 0.0
238
1 - - 0.0
253
1 - - 0.0
258
1 - - 0.0
248
1 - - 0.0
211
1 - - 0.0
236
1 - - 0.0
218
1 - - 0.0
234
1 - - 0.0
221
1 - - 0.0
260
1 - - 0.0
227
1 - - 0.0
264
1 - - 0.0
255
1 - - 0.0
274
1 - - 0.0
250
1 - - 0.0
276
1 - - 0.0
259
1 - - 0.0
249
1 - - 0.0
240
1 - - 0.0
230
1 - - 0.0
214
1 - - 0.0
239
1 - - 0.0
269
1 - - 0.0
219
1 - - 0.0
220
1 - - 0.0
226
1 - - 0.0
244
1 - - 0.0
237
1 - - 0.0
235
1 - - 0.0
265
1 - - 0.0
275
1 - - 0.0
251
1 - - 0.0
256
1 - - 0.0
215
1 - - 0.0
245
1 - - 0.0
241
1 - - 0.0
270
1 - - 0.0
266
1 - - 0.0
231
1 - - 0.0
261
1 - - 0.0
223
1 - - 0.0
216
1 - - 0.0
277
1 - - 0.0