The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Birnavirus VP3 protein, domain 2

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Birnavirus VP3 protein, domain 2

Structural domains comprising this superfamily share the structure of the C-terminal domain, designated domain 2, of the multifunctional birnavirus protein VP3, involved in virus morphogenesis. VP3 interacts with the structural protein VP2, with the double-stranded RNA genome, and with the virus-encoded, RNA-dependent RNA polymerase (RdRP), VP1, playing a role in both viral capsid formation, recruitment of VP1 into the capsid and encapsidation of the viral genome. The fold of this domain shows significant structural similarities with different transcription regulation factors which suggests it mediates interaction with both the genome and RdRP PMID:18184581.

GO Diversity

Unique GO annotations
1 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
19 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 2
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Unique EC:
Unique GO: 1
Unique Species: 19