The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
621
3D
3t3zD00 - 90.1
2
427
3D
6cizD00 - 96.5
18
383
3D
5de9B00 - 99.3
3
315 - - 93.0
4
311
3D
5tfuD00 - 95.5
40
301
3D
6h1sB00 - 94.9
6
224
3D
3k9yB00 - 92.3
5
221 - - 90.6
7
209 - - 96.4
15
201
3D
4zgxL00 - 94.8
8
196 - - 92.6
9
191 - - 88.1
10
190 - - 93.5
11
185 - - 97.9
12
173 - - 94.6
13
171 - - 74.2
14
154 - - 86.5
16
147 - - 90.1
17
141 - - 94.8
24
137
3D
3dskB00 - 93.7
19
131 - - 96.3
20
128 - - 93.0
21
126 - - 95.7
22
125 - - 95.7
23
123 - - 96.8
25
prostacyclin
122
3D
3b6hB00 - 95.1
27
120
3D
3ld6B00 - 72.4
26
118 - - 95.0
31
112
3D
4j14A00 - 95.6
32
110
3D
5jl9A00 - 77.8
28
108 - - 93.6
30
108
3D
3dl9B00 - 75.2
29
107 - - 91.4
34
101
3D
3v8dB00 - 76.7
33
99
3D
4ze2A01 - 91.7
238
96
3D
4ruiF00 - 53.5
96
95
3D
6mjmA00 - 46.7
35
87 - - 95.7
36
85 - - 91.6
37
85 - - 96.3
38
84 - - 89.1
39
83 - - 94.7
41
78 - - 72.0
42
76 - - 96.9
43
75 - - 91.9
44
71 - - 87.6
49
70
3D
4y8wC00 - 94.9
45
70 - - 76.5
46
67 - - 74.8
47
66 - - 92.1
48
63 - - 85.2
142
59
3D
5op9A00 - 8.8
50
55 - - 94.1
51
Fum15
50 - - 90.0
271
48
3D
4umzB00 - 7.5
52
48 - - 75.1
53
47 - - 73.5
55
46 - - 93.4
54
46 - - 79.4
56
45 - - 77.2
58
44 - - 84.2
57
44 - - 76.8
59
44 - - 94.5
60
43 - - 85.1
61
42 - - 62.1
62
40 - - 79.5
63
39 - - 94.2
64
35 - - 90.6
65
34 - - 84.2
68
31 - - 91.7
66
31 - - 74.0
67
31 - - 85.0
69
Eurofung
30 - - 91.1
71
28 - - 46.9
95
28
3D
3tikD00 - 27.7
70
28 - - 90.6
299
27
3D
5xxiA00 - 47.6
72
27 - - 95.7
73
26 - - 69.1
76
24 - - 92.3
74
24 - - 36.8
120
24
3D
2w0bA00 - 4.6
75
24 - - 76.4
78
23 - - 94.3
77
23 - - 33.4
80
22 - - 62.9
79
22 - - 73.5
103
22
3D
3iw2A00 - 27.1
81
22 - - 92.3
84
21 - - 76.8
82
21 - - 18.5
83
21 - - 19.7
87
20 - - 22.0
85
20 - - 41.1
86
20 - - 77.4
88
19 - - 90.0
89
18 - - 43.6
91
17 - - 96.6
90
17 - - 82.0
377
16
3D
4lhtB00 - 7.5
92
16 - - 71.9
94
16 - - 96.0
93
16 - - 85.1
98
15 - - 92.9
140
15
3D
5lieB00 - 0.3
97
15 - - 94.9
101
14 - - 90.3
102
14 - - 85.7
100
14 - - 53.3
99
14 - - 65.5
104
14 - - 88.1
185
14
3D
2zqxC00 - 24.1
107
13 - - 31.0
110
13 - - 80.2
108
13 - - 0.0
105
13 - - 41.8
109
13 - - 15.1
106
13 - - 74.0
127
12
3D
2wm5A00 - 1.9
119
12 - - 72.9
116
12 - - 10.6
112
12 - - 48.5
115
12 - - 71.4
117
12 - - 0.0
111
12 - - 62.3
118
12 - - 15.5
113
12 - - 71.8
114
12 - - 76.7
121
11 - - 14.6
128
10 - - 0.0
130
10 - - 91.6
122
10 - - 69.9
125
10 - - 68.7
129
10 - - 93.8
124
10 - - 34.2
126
10 - - 93.6
169
E
10
3D
3el3B00 - 11.7
123
10 - - 64.2
136
9 - - 89.9
132
9 - - 34.3
135
9 - - 47.3
273
9
3D
2xfhA00 - 10.6
131
9 - - 46.9
133
9 - - 0.0
134
9 - - 13.9
144
8 - - 13.3
138
8 - - 72.2
137
8 - - 68.1
139
8 - - 71.6
145
8 - - 75.8
143
8 - - 15.5
141
8 - - 7.7
146
8 - - 87.6
153
7 - - 10.0
160
7 - - 74.6
151
7 - - 44.7
155
7 - - 19.3
154
7 - - 0.0
158
Eurofung
7 - - 85.3
147
S
7 - - 63.3
149
7 - - 54.0
156
7 - - 6.5
196
7
3D
5hdiB00 - 0.0
152
7 - - 16.8
150
7 - - 78.7
159
7 - - 73.8
148
7 - - 30.6
157
7 - - 65.6
180
6 - - 42.2
177
6 - - 75.5
170
6 - - 0.0
182
6 - - 80.5
167
6 - - 13.4
163
6 - - 76.0
175
6 - - 68.5
181
6 - - 70.3
165
6 - - 88.8
173
6 - - 0.0
168
6 - - 7.8
178
6 - - 79.7
171
6 - - 0.0
161
6 - - 75.3
176
6 - - 67.3
162
6 - - 78.4
174
6 - - 11.5
371
6
3D
2ve4B00 - 0.0
172
6 - - 0.0
179
6 - - 66.7
166
6 - - 12.9
164
6 - - 77.3
193
5 - - 6.6
189
5 - - 46.7
205
5 - - 63.9
191
5 - - 16.2
187
5 - - 32.8
207
5 - - 77.1
198
5 - - 9.9
202
5 - - 56.7
184
5 - - 39.0
186
Eurofung
5 - - 31.7
209
5 - - 76.7
210
5 - - 74.4
206
5 - - 74.8
194
5 - - 8.3
200
5 - - 91.3
197
5 - - 7.7
192
5 - - 15.6
208
5 - - 79.7
199
5 - - 13.9
195
5 - - 0.0
201
5 - - 17.2
188
Eurofung
5 - - 80.2
183
5 - - 40.2
190
5 - - 26.9
203
5 - - 53.4
204
5 - - 68.5
211
4 - - 35.6
236
4 - - 79.0
218
4 - - 54.5
234
4 - - 60.2
221
4 - - 75.0
212
4 - - 17.9
227
4 - - 0.0
232
4 - - 45.5
225
4 - - 9.0
375
4
3D
4dnjA00 - 0.0
240
4 - - 88.4
230
4 - - 5.9
214
4 - - 21.6
229
4 - - 5.5
222
4 - - 82.4
217
4 - - 51.1
239
4 - - 74.1
219
4 - - 51.7
242
4 - - 76.3
220
4 - - 52.5
226
4 - - 10.5
237
4 - - 32.5
235
4 - - 72.9
213
4 - - 54.4
224
4 - - 9.8
215
4 - - 65.5
233
4 - - 51.3
241
4 - - 87.9
231
4 - - 9.1
228
4 - - 0.3
223
4 - - 10.8
216
4 - - 39.0
285
3 - - 32.2
288
3 - - 38.9
246
3 - - 23.0
260
3 - - 13.8
272
3 - - 0.0
287
3 - - 60.2
294
3 - - 65.6
262
3 - - 1.6
264
3 - - 4.2
255
3 - - 35.5
274
3 - - 1.6
250
3 - - 29.7
278
3 - - 0.0
257
3 - - 56.7
276
3 - - 4.6
259
3 - - 73.9
249
3 - - 9.2
281
3 - - 0.0
269
3 - - 0.3
284
3 - - 51.9
247
3 - - 12.2
289
3 - - 68.3
297
3 - - 41.4
290
3 - - 63.3
252
3 - - 24.8
283
3 - - 37.8
244
3 - - 11.6
295
3 - - 23.4
286
3 - - 55.2
254
3 - - 41.3
265
3 - - 0.0
296
3 - - 78.2
275
3 - - 0.0
251
3 - - 11.2
279
3 - - 1.8
256
3 - - 61.7
263
3 - - 0.0
293
3 - - 40.9
245
3 - - 24.0
267
3 - - 11.9
292
3 - - 72.9
291
3 - - 71.4
280
3 - - 65.1
270
3 - - 0.6
266
3 - - 0.0
243
3 - - 17.4
261
3 - - 0.0
268
3 - - 7.1
282
3 - - 0.0
253
3 - - 21.7
277
3 - - 4.6
258
3 - - 66.3
248
3 - - 29.3
463
2 - - 36.3
458
2 - - 34.0
451
2 - - 35.4
454
2 - - 31.0
378
2 - - 7.8
325
2 - - 28.4
350
2 - - 0.0
337
2 - - 38.7
340
2 - - 46.4
311
2 - - 32.2
389
Eurofung
2 - - 3.0
391
2 - - 3.8
410
2 - - 5.0
430
2 - - 36.0
447
2 - - 26.2
415
2 - - 39.0
438
2 - - 10.1
444
2 - - 13.3
417
2 - - 39.4
381
2 - - 6.4
308
2 - - 31.3
373
2 - - 0.0
301
2 - - 10.2
456
2 - - 32.4
366
2 - - 0.0
400
2 - - 0.0
468
2 - - 42.3
475
2 - - 37.2
413
2 - - 1.4
349
2 - - 2.3
432
2 - - 9.9
333
2 - - 36.3
323
2 - - 32.1
446
2 - - 23.3
359
2 - - 0.0
330
2 - - 36.0
360
Eurofung
2 - - 0.0
393
2 - - 9.2
449
2 - - 29.3
353
2 - - 2.5
303
2 - - 31.1
387
2 - - 1.0
461
2 - - 37.2
425
2 - - 48.4
424
2 - - 39.3
395
2 - - 0.0
347
2 - - 7.4
434
2 - - 0.0
442
2 - - 34.8
320
2 - - 30.1
465
2 - - 43.3
361
2 - - 0.0
412
2 - - 0.0
385
2 - - 0.4
307
2 - - 27.6
326
2 - - 34.6
335
2 - - 38.5
440
2 - - 39.7
467
2 - - 41.2
474
2 - - 43.0
315
2 - - 18.2
338
2 - - 44.4
305
2 - - 28.7
328
2 - - 35.8
363
2 - - 7.1
472
2 - - 37.4
317
2 - - 23.2
313
2 - - 11.1
397
2 - - 0.0
459
2 - - 35.3
401
2 - - 0.2
319
2 - - 27.0
404
2 - - 1.5
344
2 - - 43.4
357
2 - - 7.5
455
2 - - 37.5
336
2 - - 36.6
457
2 - - 35.3
383
2 - - 2.8
419
2 - - 38.1
406
2 - - 5.7
365
2 - - 10.2
470
2 - - 39.7
421
2 - - 44.5
390
2 - - 0.0
408
Eurofung
2 - - 0.0
443
2 - - 43.6
358
Eurofung
2 - - 0.0
331
2 - - 39.1
437
2 - - 3.0
431
2 - - 35.3
382
2 - - 0.0
418
2 - - 42.6
348
2 - - 3.2
388
2 - - 10.7
364
2 - - 9.6
367
2 - - 4.0
460
2 - - 36.9
453
2 - - 35.4
324
2 - - 21.4
351
2 - - 3.9
379
2 - - 10.6
452
2 - - 33.6
342
2 - - 40.0
341
2 - - 34.3
312
2 - - 30.2
405
Eurofung
2 - - 0.0
370
2 - - 1.6
309
2 - - 30.4
416
2 - - 37.1
380
2 - - 0.0
300
2 - - 28.0
392
Eurofung
2 - - 0.0
399
2 - - 0.0
436
2 - - 2.3
386
2 - - 5.2
445
2 - - 22.4
329
2 - - 36.8
441
2 - - 11.6
346
2 - - 16.0
427
2 - - 33.9
352
2 - - 0.0
426
2 - - 42.4
369
2 - - 0.7
372
2 - - 1.8
428
2 - - 36.2
462
2 - - 40.0
414
2 - - 36.8
394
2 - - 0.9
476
2 - - 43.1
322
2 - - 33.1
469
2 - - 36.7
310
2 - - 10.7
354
2 - - 6.1
332
2 - - 35.8
368
2 - - 0.0
316
2 - - 31.5
374
2 - - 0.6
429
2 - - 35.0
409
2 - - 4.5
327
2 - - 32.7
471
2 - - 45.3
314
2 - - 29.8
355
2 - - 2.1
433
2 - - 3.1
334
2 - - 34.9
423
2 - - 41.4
422
2 - - 38.8
302
2 - - 29.3
402
2 - - 2.6
464
2 - - 41.5
439
2 - - 3.3
362
2 - - 1.4
411
2 - - 6.7
398
2 - - 0.0
384
2 - - 1.1
407
2 - - 8.0
376
2 - - 2.1
298
2 - - 18.7
343
2 - - 36.6
321
2 - - 33.5
435
2 - - 0.0
339
2 - - 37.0
345
2 - - 41.5
420
2 - - 40.5
448
2 - - 32.6
304
2 - - 30.8
396
2 - - 2.2
306
2 - - 7.7
403
2 - - 0.0
466
2 - - 41.2
450
2 - - 32.3
318
2 - - 25.1
473
2 - - 36.2
356
2 - - 1.5
560
1 - - 0.0
798
1 - - 0.0
512
1 - - 0.0
517
1 - - 0.0
722
1 - - 0.0
634
1 - - 0.0
578
1 - - 0.0
695
1 - - 0.0
728
1 - - 0.0
742
1 - - 0.0
540
1 - - 0.0
684
1 - - 0.0
571
1 - - 0.0
825
1 - - 0.0
495
1 - - 0.0
758
1 - - 0.0
706
1 - - 0.0
834
1 - - 0.0
594
1 - - 0.0
486
1 - - 0.0
569
1 - - 0.0
686
1 - - 0.0
586
1 - - 0.0
690
1 - - 0.0
536
1 - - 0.0
480
1 - - 0.0
508
1 - - 0.0
558
1 - - 0.0
784
1 - - 0.0
573
1 - - 0.0
762
1 - - 0.0
638
1 - - 0.0
734
1 - - 0.0
506
1 - - 0.0
661
1 - - 0.0
581
1 - - 0.0
678
1 - - 0.0
773
1 - - 0.0
652
1 - - 0.0
493
S
1 - - 0.0
796
1 - - 0.0
844
1 - - 0.0
775
1 - - 0.0
534
1 - - 0.0
746
1 - - 0.0
744
1 - - 0.0
633
1 - - 0.0
700
1 - - 0.0
764
1 - - 0.0
515
1 - - 0.0
606
1 - - 0.0
724
1 - - 0.0
666
1 - - 0.0
519
1 - - 0.0
708
1 - - 0.0
710
1 - - 0.0
545
1 - - 0.0
588
1 - - 0.0
646
1 - - 0.0
756
1 - - 0.0
542
1 - - 0.0
810
1 - - 0.0
574
1 - - 0.0
660
1 - - 0.0
526
1 - - 0.0
566
Cytochrome P450 family 71 subfamily A polypeptide 12
1 - - 0.0
806
1 - - 0.0
604
1 - - 0.0
556
1 - - 0.0
717
1 - - 0.0
477
1 - - 0.0
815
1 - - 0.0
671
1 - - 0.0
692
1 - - 0.0
663
1 - - 0.0
510
1 - - 0.0
766
1 - - 0.0
658
1 - - 0.0
549
1 - - 0.0
659
1 - - 0.0
682
1 - - 0.0
788
1 - - 0.0
614
1 - - 0.0
501
1 - - 0.0
490
1 - - 0.0
626
1 - - 0.0
583
1 - - 0.0
782
1 - - 0.0
809
1 - - 0.0
591
1 - - 0.0
832
1 - - 0.0
736
1 - - 0.0
539
1 - - 0.0
781
1 - - 0.0
828
1 - - 0.0
520
1 - - 0.0
532
1 - - 0.0
584
1 - - 0.0
665
1 - - 0.0
649
1 - - 0.0
689
1 - - 0.0
648
1 - - 0.0
642
1 - - 0.0
727
1 - - 0.0
811
1 - - 0.0
819
1 - - 0.0
776
1 - - 0.0
801
1 - - 0.0
830
1 - - 0.0
754
1 - - 0.0
479
1 - - 0.0
704
1 - - 0.0
681
1 - - 0.0
619
1 - - 0.0
698
1 - - 0.0
621
1 - - 0.0
524
1 - - 0.0
554
1 - - 0.0
552
1 - - 0.0
598
1 - - 0.0
780
1 - - 0.0
602
1 - - 0.0
841
1 - - 0.0
612
1 - - 0.0
701
1 - - 0.0
481
1 - - 0.0
564
1 - - 0.0
817
1 - - 0.0
563
1 - - 0.0
731
1 - - 0.0
657
1 - - 0.0
768
1 - - 0.0
503
1 - - 0.0
673
1 - - 0.0
576
1 - - 0.0
761
1 - - 0.0
738
1 - - 0.0
484
1 - - 0.0
544
1 - - 0.0
623
1 - - 0.0
628
1 - - 0.0
733
1 - - 0.0
630
1 - - 0.0
748
1 - - 0.0
608
1 - - 0.0
711
1 - - 0.0
546
1 - - 0.0
537
1 - - 0.0
522
1 - - 0.0
667
1 - - 0.0
741
1 - - 0.0
714
1 - - 0.0
529
1 - - 0.0
823
1 - - 0.0
729
1 - - 0.0
771
1 - - 0.0
808
1 - - 0.0
845
1 - - 0.0
735
1 - - 0.0
516
1 - - 0.0
702
1 - - 0.0
636
1 - - 0.0
561
1 - - 0.0
600
1 - - 0.0
821
1 - - 0.0
696
1 - - 0.0
550
1 - - 0.0
505
1 - - 0.0
670
1 - - 0.0
837
1 - - 0.0
592
1 - - 0.0
625
1 - - 0.0
712
1 - - 0.0
530
1 - - 0.0
763
1 - - 0.0
793
1 - - 0.0
570
1 - - 0.0
654
1 - - 0.0
655
1 - - 0.0
491
1 - - 0.0
799
1 - - 0.0
840
1 - - 0.0
597
1 - - 0.0
559
1 - - 0.0
737
1 - - 0.0
580
1 - - 0.0
767
1 - - 0.0
805
1 - - 0.0
846
1 - - 0.0
572
1 - - 0.0
675
1 - - 0.0
527
1 - - 0.0
833
1 - - 0.0
548
1 - - 0.0
739
1 - - 0.0
662
1 - - 0.0
783
1 - - 0.0
789
1 - - 0.0
772
1 - - 0.0
627
1 - - 0.0
715
1 - - 0.0
653
1 - - 0.0
509
1 - - 0.0
716
1 - - 0.0
485
1 - - 0.0
685
1 - - 0.0
778
1 - - 0.0
743
1 - - 0.0
523
1 - - 0.0
720
1 - - 0.0
723
1 - - 0.0
637
1 - - 0.0
595
1 - - 0.0
488
1 - - 0.0
752
1 - - 0.0
835
1 - - 0.0
579
1 - - 0.0
535
1 - - 0.0
683
1 - - 0.0
541
1 - - 0.0
765
1 - - 0.0
507
1 - - 0.0
567
1 - - 0.0
824
1 - - 0.0
800
1 - - 0.0
496
1 - - 0.0
605
1 - - 0.0
607
1 - - 0.0
813
1 - - 0.0
644
1 - - 0.0
759
1 - - 0.0
694
1 - - 0.0
816
1 - - 0.0
568
1 - - 0.0
791
1 - - 0.0
525
1 - - 0.0
787
1 - - 0.0
582
1 - - 0.0
557
1 - - 0.0
718
1 - - 0.0
672
1 - - 0.0
769
1 - - 0.0
803
1 - - 0.0
751
1 - - 0.0
691
1 - - 0.0
677
1 - - 0.0
650
1 - - 0.0
590
1 - - 0.0
664
1 - - 0.0
617
1 - - 0.0
651
1 - - 0.0
498
1 - - 0.0
483
1 - - 0.0
629
1 - - 0.0
500
1 - - 0.0
790
1 - - 0.0
533
1 - - 0.0
843
1 - - 0.0
632
1 - - 0.0
514
1 - - 0.0
610
1 - - 0.0
725
1 - - 0.0
513
1 - - 0.0
615
1 - - 0.0
797
1 - - 0.0
645
1 - - 0.0
635
1 - - 0.0
575
1 - - 0.0
709
1 - - 0.0
589
1 - - 0.0
699
1 - - 0.0
687
1 - - 0.0
818
1 - - 0.0
543
1 - - 0.0
826
1 - - 0.0
757
phenobarbital-inducible
1 - - 0.0
745
1 - - 0.0
603
1 - - 0.0
565
1 - - 0.0
620
1 - - 0.0
730
1 - - 0.0
611
1 - - 0.0
492
1 - - 0.0
511
1 - - 0.0
842
1 - - 0.0
795
1 - - 0.0
812
1 - - 0.0
489
1 - - 0.0
585
1 - - 0.0
794
1 - - 0.0
732
1 - - 0.0
674
1 - - 0.0
622
1 - - 0.0
502
1 - - 0.0
553
1 - - 0.0
747
1 - - 0.0
555
1 - - 0.0
538
1 - - 0.0
680
1 - - 0.0
679
1 - - 0.0
831
1 - - 0.0
521
1 - - 0.0
647
1 - - 0.0
786
1 - - 0.0
740
1 - - 0.0
719
1 - - 0.0
827
1 - - 0.0
820
1 - - 0.0
668
1 - - 0.0
688
1 - - 0.0
750
1 - - 0.0
774
1 - - 0.0
693
1 - - 0.0
593
1 - - 0.0
770
1 - - 0.0
641
1 - - 0.0
838
1 - - 0.0
616
1 - - 0.0
640
1 - - 0.0
804
1 - - 0.0
755
1 - - 0.0
777
1 - - 0.0
562
1 - - 0.0
518
1 - - 0.0
497
1 - - 0.0
705
1 - - 0.0
478
1 - - 0.0
836
1 - - 0.0
785
1 - - 0.0
599
1 - - 0.0
587
1 - - 0.0
609
1 - - 0.0
601
1 - - 0.0
822
1 - - 0.0
779
1 - - 0.0
551
1 - - 0.0
504
1 - - 0.0
753
1 - - 0.0
697
1 - - 0.0
726
1 - - 0.0
707
1 - - 0.0
624
1 - - 0.0
792
1 - - 0.0
656
1 - - 0.0
814
1 - - 0.0
760
1 - - 0.0
749
1 - - 0.0
531
1 - - 0.0
829
1 - - 0.0
596
1 - - 0.0
613
1 - - 0.0
721
1 - - 0.0
669
1 - - 0.0
639
1 - - 0.0
494
1 - - 0.0
487
1 - - 0.0
577
1 - - 0.0
643
1 - - 0.0
713
1 - - 0.0
676
1 - - 0.0
547
1 - - 0.0
631
1 - - 0.0
482
1 - - 0.0
499
1 - - 0.0
839
1 - - 0.0
618
1 - - 0.0
703
1 - - 0.0
802
1 - - 0.0
528
1 - - 0.0
807
1 - - 0.0