The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Topoisomerase I, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
446
3D
4rulA02 - 75.2
2
322
3D
5gveA02 - 78.2
3
292 - - 92.7
4
200
3D
2o5eB02 - 77.9
5
24 - - 40.2
6
20 - - 23.3
7
19 - - 14.8
8
14 - - 47.5
9
13 - - 29.4
11
11 - - 20.7
10
11 - - 33.0
12
9 - - 38.0
13
9 - - 3.2
14
7 - - 1.5
15
7 - - 44.4
20
6
3D
4chtA02 - 50.1
16
6 - - 13.8
18
5 - - 52.0
17
5 - - 6.9
19
4 - - 9.5
21
3 - - 13.3
22
3 - - 8.2
23
3 - - 0.0
24
3 - - 31.7
29
2 - - 9.1
26
2 - - 22.4
31
2 - - 44.3
27
2 - - 1.4
28
2 - - 0.0
30
2 - - 0.0
25
2 - - 14.3
32
2 - - 30.9
39
1 - - 0.0
36
1 - - 0.0
37
1 - - 0.0
33
1 - - 0.0
38
1 - - 0.0
35
1 - - 0.0
34
TopA
1 - - 0.0