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CATH Superfamily 1.10.437.10

Blc2-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Blc2-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
2
Induced myeloid leukemia cell differentiation protein Mcl-1
259
3D
 5vx2C01 - 71.0
3
Bcl-2-like protein 1
139
3D
 4yk9F00 - 80.4
1
Bcl-2-like protein 2
110
3D
 1zy3A00 - 62.6
4
apoptosis regulator BAX isoform X2
108
3D
 5w5xA00 - 75.8
6
Apoptosis regulator Bcl-2
86
3D
 2xa0B00 - 83.2
8
Bcl-2-related protein A1
83
3D
 2voiA00 - 86.5
5
bcl-2-related ovarian killer protein
83 - - 70.9
7
bcl-2 homologous antagonist/killer
78
3D
 5fmiA00 - 84.7
9
Uncharacterized protein, isoform A
51 - - 95.3
10
BH3-interacting domain death agonist
50
3D
 1ddbA00 - 91.9
11
BCL2 like 13
42 - - 52.2
12
Bcl-2-related protein A1
28 - - 31.6
13
Protein F1
25
3D
 2vtyA00 - 21.4
14
Bcl-2-like protein 10
23
3D
 4b4sA01 - 87.0
15
BCL2 like 13
19 - - 80.3
16
bcl-2-like protein 1 isoform X2
18 - - 12.9
17
MCL1, BCL2 family apoptosis regulator
15 - - 88.9
18
BCL2 like 15
12 - - 72.3
19
Apoptosis facilitator Bcl-2-like protein 14
11 - - 32.6
22
Apoptosis regulator ced-9
10
3D
 2a5yA00 - 80.9
20
BCL2 like 10
6 - - 41.5
21
Apoptosis regulator BHRF1
5 - - 0.7
26
BCL2 associated X, apoptosis regulator
4 - - 12.1
25
BCL2 like 13
4 - - 5.2
23
Predicted protein
4 - - 76.3
27
Anti-apoptotic protein NR13
4 - - 7.6
24
BCL-WAV
4 - - 52.5
29
Bcl2-associated X protein b
3 - - 2.3
33
Predicted protein
3 - - 75.2
32
Bcl-2-related ovarian killer protein homolog B
3 - - 0.0
31
BH3-interacting domain death agonist
3 - - 4.3
28
Uncharacterized protein
3 - - 75.4
30
ORF 16
3 - - 0.0
39
Uncharacterized protein
2 - - 5.5
35
Predicted protein
2 - - 37.4
36
bcl-2-related ovarian killer protein homolog B isoform X1
2 - - 41.1
38
Zgc:153993
2 - - 30.8
40
Apoptosis regulator R11
2 - - 1.3
34
Predicted protein
2 - - 38.3
37
apoptosis regulator Bcl-2
2 - - 40.0
41
Predicted protein
2 - - 9.5
58
Uncharacterized protein
1 - - 0.0
43
Predicted protein
1 - - 0.0
61
Uncharacterized protein
1 - - 0.0
51
Uncharacterized protein
1 - - 0.0
48
Uncharacterized protein
1 - - 0.0
53
BCL2-associated X, apoptosis regulator a
1 - - 0.0
55
BCL2 associated X, apoptosis regulator
1 - - 0.0
57
Uncharacterized protein
1 - - 0.0
46
Uncharacterized protein
1 - - 0.0
44
Uncharacterized protein
1 - - 0.0
66
Uncharacterized protein
1 - - 0.0
59
BH3 interacting domain death agonist
1 - - 0.0
62
Predicted protein
1 - - 0.0
49
Uncharacterized protein
1 - - 0.0
64
Uncharacterized protein
1 - - 0.0
45
Uncharacterized protein
1 - - 0.0
42
Uncharacterized protein
1 - - 0.0
60
Uncharacterized protein
1 - - 0.0
50
Uncharacterized protein
1 - - 0.0
47
Uncharacterized protein
1 - - 0.0
52
MCL1 apoptosis regulator, BCL2 family member b
1 - - 0.0
65
BCL2-associated X, apoptosis regulator a
1 - - 0.0
63
Uncharacterized protein
1 - - 0.0
56
Uncharacterized protein
1 - - 0.0
54
Predicted protein
1 - - 0.0