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CATH Superfamily 1.10.340.40

Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain

Structural domains comprising this superfamily share the structure of the N-terminal domain of the nuclear abundant poly(A) RNA-bind protein 2 (Nab2), a yeast heterogeneous nuclear ribonucleoprotein that modulates poly(A) tail length and mRNA. The N-terminal domains mediates interactions with the C-terminal globular domain, Myosin-like protein 1 and the mRNA export factor, Gfd1. An essential hydrophobic Phe73 patch on the N-terminal domain is thought to be an important component of the interface between Nab2 and Mlp1 PMID:18190927, (INTERPRO:IPR021083).

GO Diversity

Unique GO annotations
20 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
643 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 4
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 3
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 5
Function
Unique EC:
Unique GO: 20
Taxonomy
Unique Species: 643