The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
DnaJ domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
779
3D
2guzO00 - 96.1
2
603
3D
2qwrB00 - 96.9
3
468 - - 72.7
4
Hsp40
391 - - 83.3
6
376
3D
2guzP00 - 98.9
5
Hsp40
372 - - 79.0
7
Hsp40
357 - - 87.1
8
342
3D
1fpoC01 - 79.5
9
305 - - 85.6
10
283 - - 40.8
11
277 - - 79.3
12
262 - - 78.4
13
260 - - 29.1
14
254 - - 95.4
15
217 - - 82.3
16
Hsp40
214 - - 89.9
17
209
3D
2n05A00 - 75.2
18
Hsp40
184 - - 72.6
19
184
3D
2ys8A00 - 85.3
20
178 - - 92.3
21
Hsp40
174
3D
2lgwA00 - 82.6
22
164 - - 72.2
23
155
3D
1iurA01 - 36.2
24
Hsp40
153 - - 50.1
25
148 - - 72.9
27
Hsp40
144 - - 80.7
26
144 - - 72.9
29
143
3D
3apqB01 - 71.8
28
142 - - 87.0
30
133 - - 73.2
31
131 - - 88.1
32
129 - - 76.3
34
128
3D
4j7zF00 - 94.2
33
127 - - 89.4
35
122 - - 88.8
36
118
3D
2qsaA00 - 87.5
37
113 - - 80.5
38
106 - - 82.8
39
Npl1
103 - - 93.0
40
100 - - 67.4
41
99 - - 94.4
42
86
3D
3bvoB01 - 85.9
43
85
3D
3ag7A00 - 83.3
44
Hsp40
83 - - 53.1
45
82 - - 76.8
46
82 - - 87.3
47
80 - - 74.4
49
79
3D
2ctqA01 - 67.6
48
79 - - 85.4
51
77 - - 39.7
50
77 - - 75.9
52
73 - - 88.8
53
69 - - 87.8
54
67
3D
2ctrA00 - 68.6
56
Hsp40
65
3D
2l6lA01 - 90.7
55
64 - - 90.2
57
61 - - 38.6
58
59 - - 79.6
59
57 - - 85.4
60
Hsp40
55
3D
2yuaA01 - 81.3
62
53 - - 70.6
61
Hsp40
53 - - 30.1
63
53 - - 91.6
64
52 - - 77.9
65
51 - - 71.9
66
51 - - 77.1
67
50 - - 74.5
68
43 - - 67.9
69
40 - - 83.6
70
40 - - 91.5
71
39 - - 70.4
72
38 - - 85.6
73
35 - - 93.2
74
30 - - 75.1
75
29 - - 76.7
76
28 - - 88.3
77
28 - - 86.8
78
27 - - 72.7
82
27 - - 89.0
79
27 - - 75.0
81
27 - - 86.2
80
NAD
P
27 - - 75.0
83
26 - - 70.3
84
25 - - 68.6
87
24 - - 89.6
85
24 - - 61.6
89
24 - - 63.2
86
24 - - 68.6
92
24
3D
4rwuA00 - 56.8
88
24 - - 13.6
90
23 - - 80.2
94
22 - - 65.8
109
22
3D
3uo3B01 - 70.1
93
22 - - 80.8
91
22 - - 82.8
95
22 - - 83.8
96
21 - - 80.7
98
20 - - 83.1
100
20 - - 74.7
99
20 - - 63.7
97
20 - - 74.8
101
19 - - 55.3
102
19 - - 15.9
104
19 - - 54.9
103
19 - - 67.3
106
19 - - 88.8
105
19 - - 35.7
107
18 - - 80.6
110
AFU_orthologue AFUA_2G13210
18 - - 86.8
108
18 - - 2.0
118
17 - - 7.7
119
17 - - 68.9
113
Hsp40
17 - - 90.6
116
17 - - 82.8
112
17 - - 81.0
114
17 - - 74.6
115
17 - - 74.9
117
17 - - 5.4
111
17 - - 10.2
124
16 - - 71.0
120
16 - - 48.2
122
16 - - 0.0
125
16 - - 58.5
121
16 - - 11.3
123
16 - - 6.3
127
15 - - 14.1
161
15
3D
1gh6A01 - 81.1
126
15 - - 32.6
128
15 - - 7.0
129
14 - - 89.2
130
Caj1
14 - - 80.3
135
13 - - 72.9
136
13 - - 57.9
138
13 - - 41.7
137
13 - - 72.4
131
13 - - 2.6
132
13 - - 9.2
133
13 - - 1.3
134
13 - - 4.0
139
12 - - 67.9
142
12 - - 76.1
140
12 - - 88.9
143
12 - - 70.3
141
12 - - 47.1
153
11 - - 49.1
145
11 - - 66.1
152
11 - - 70.6
144
11 - - 77.2
151
11 - - 50.7
150
11 - - 7.7
148
11 - - 2.6
147
11 - - 40.9
149
11 - - 32.0
146
11 - - 42.5
160
10 - - 55.9
155
10 - - 38.6
154
10 - - 73.5
159
10 - - 73.3
158
10 - - 83.4
157
10 - - 0.0
156
10 - - 13.4
163
9 - - 44.5
162
9 - - 18.1
165
9 - - 9.5
166
9 - - 40.4
164
9 - - 18.9
168
8 - - 13.4
177
Hsp40
8 - - 60.3
171
8 - - 25.7
176
8 - - 46.2
170
8 - - 63.1
167
8 - - 39.7
175
8 - - 73.7
174
8 - - 6.7
169
8 - - 35.2
172
8 - - 1.8
173
8 - - 59.4
178
7 - - 9.1
180
7 - - 57.6
189
7 - - 69.7
187
7 - - 75.1
182
7 - - 43.1
184
7 - - 9.0
181
7 - - 41.4
188
7 - - 74.1
183
7 - - 6.3
190
7 - - 81.7
186
7 - - 14.4
179
Prokaryotic heat shock protein
7 - - 33.8
185
7 - - 10.0
194
6 - - 74.2
193
6 - - 50.2
200
6 - - 1.7
197
6 - - 4.5
191
6 - - 38.9
192
6 - - 28.7
199
DnaJ family
6 - - 10.7
198
6 - - 0.0
202
6 - - 10.3
195
6 - - 79.2
201
6 - - 21.0
203
6 - - 64.9
204
6 - - 61.4
196
Hsp40
6 - - 5.5
206
5 - - 72.1
220
Hsp40
5 - - 64.2
211
5 - - 13.6
218
5 - - 13.3
221
5 - - 71.3
205
5 - - 73.9
213
5 - - 6.0
212
5 - - 15.1
207
5 - - 75.9
215
5 - - 8.2
208
5 - - 15.3
214
5 - - 11.4
222
5 - - 86.9
217
Hsp40
5 - - 36.7
223
5 - - 80.4
209
5 - - 11.4
216
5 - - 18.6
210
5 - - 11.9
219
5 - - 1.1
226
4 - - 34.3
236
4 - - 80.0
234
4 - - 44.0
244
4 - - 67.6
246
Prokaryotic heat shock protein
4 - - 17.8
237
4 - - 6.9
235
4 - - 84.0
224
4 - - 84.1
251
4 - - 55.5
227
4 - - 58.7
232
4 - - 39.7
225
4 - - 15.3
250
4 - - 64.2
245
4 - - 56.3
233
4 - - 45.3
241
4 - - 0.0
249
4 - - 70.0
240
4 - - 8.3
230
4 - - 69.0
229
4 - - 66.9
239
4 - - 0.0
243
4 - - 11.6
231
4 - - 60.7
247
4 - - 31.0
228
4 - - 36.7
238
4 - - 0.0
248
4 - - 50.8
242
4 - - 12.7
285
3 - - 42.5
288
3 - - 56.4
260
3 - - 7.7
286
3 - - 41.7
254
3 - - 4.6
265
3 - - 4.5
272
3 - - 5.0
287
3 - - 70.1
275
3 - - 9.4
262
3 - - 9.5
279
3 - - 2.8
256
3 - - 27.0
264
3 - - 1.2
255
3 - - 31.4
263
3 - - 1.2
274
3 - - 56.2
278
3 - - 2.4
267
3 - - 0.0
257
3 - - 36.1
276
3 - - 1.0
259
3 - - 8.0
280
3 - - 51.2
273
3 - - 35.7
270
3 - - 10.0
266
3 - - 5.2
281
3 - - 5.3
269
3 - - 6.9
261
3 - - 12.1
284
3 - - 37.3
268
3 - - 12.8
282
3 - - 34.0
253
3 - - 15.9
277
3 - - 0.0
258
3 - - 80.7
252
3 - - 49.8
283
3 - - 36.5
271
3 - - 3.9
331
2 - - 0.0
358
2 - - 0.0
325
2 - - 0.0
378
2 - - 40.5
350
2 - - 44.5
337
2 - - 0.0
382
2 - - 46.2
340
2 - - 3.1
311
2 - - 0.0
348
AFU_orthologue AFUA_5G03040
2 - - 0.0
364
2 - - 0.0
367
2 - - 0.0
324
2 - - 1.3
351
2 - - 42.1
379
2 - - 41.6
342
2 - - 0.0
295
2 - - 0.0
341
2 - - 12.0
312
2 - - 0.0
370
2 - - 41.1
309
2 - - 43.1
380
2 - - 21.9
300
2 - - 33.3
381
2 - - 42.9
308
Hsp40
2 - - 41.3
373
2 - - 0.0
301
2 - - 28.9
296
2 - - 2.2
366
2 - - 40.4
329
2 - - 0.0
294
2 - - 1.1
349
2 - - 0.0
346
2 - - 0.0
333
2 - - 0.0
323
2 - - 0.0
352
2 - - 16.7
369
2 - - 0.0
372
2 - - 0.0
359
2 - - 0.0
330
2 - - 0.0
360
2 - - 4.6
293
2 - - 0.0
322
2 - - 0.0
353
2 - - 0.0
375
2 - - 0.0
310
2 - - 22.8
303
2 - - 31.0
354
2 - - 0.0
332
2 - - 10.1
368
2 - - 1.1
316
2 - - 0.0
347
2 - - 3.9
292
2 - - 1.4
291
2 - - 13.5
374
2 - - 0.0
327
2 - - 0.0
320
2 - - 12.6
361
2 - - 0.0
385
2 - - 27.9
314
2 - - 1.1
307
2 - - 39.5
355
2 - - 0.0
326
AFU_orthologue AFUA_1G03520
2 - - 0.0
335
2 - - 0.0
334
2 - - 0.0
299
Hsp40
2 - - 20.3
377
2 - - 31.9
302
2 - - 30.0
315
2 - - 0.0
338
2 - - 0.0
305
2 - - 38.1
328
2 - - 0.0
363
2 - - 8.2
362
2 - - 13.3
317
2 - - 0.0
384
2 - - 41.4
376
2 - - 0.0
298
2 - - 15.8
313
2 - - 0.0
343
2 - - 0.0
321
2 - - 8.0
371
2 - - 0.0
289
2 - - 40.9
339
2 - - 0.0
345
DnaJ family
2 - - 0.0
319
2 - - 1.3
344
2 - - 0.0
357
2 - - 6.6
336
2 - - 0.0
383
2 - - 46.7
297
2 - - 13.4
290
2 - - 44.5
304
2 - - 34.6
365
2 - - 9.5
306
Prokaryotic heat shock protein
2 - - 43.2
318
2 - - 0.0
356
2 - - 19.7
443
1 - - 0.0
437
1 - - 0.0
463
1 - - 0.0
458
1 - - 0.0
451
1 - - 0.0
454
1 - - 0.0
431
1 - - 0.0
389
1 - - 0.0
418
1 - - 0.0
388
1 - - 0.0
485
1 - - 0.0
391
1 - - 0.0
460
1 - - 0.0
453
1 - - 0.0
410
1 - - 0.0
430
1 - - 0.0
447
1 - - 0.0
415
1 - - 0.0
452
1 - - 0.0
480
1 - - 0.0
438
1 - - 0.0
444
1 - - 0.0
417
1 - - 0.0
405
1 - - 0.0
416
1 - - 0.0
392
1 - - 0.0
399
1 - - 0.0
436
1 - - 0.0
456
1 - - 0.0
386
1 - - 0.0
445
Hsp40
1 - - 0.0
400
1 - - 0.0
468
1 - - 0.0
441
1 - - 0.0
475
1 - - 0.0
413
1 - - 0.0
432
1 - - 0.0
427
1 - - 0.0
446
1 - - 0.0
426
1 - - 0.0
483
1 - - 0.0
428
1 - - 0.0
414
1 - - 0.0
462
1 - - 0.0
477
1 - - 0.0
394
1 - - 0.0
476
1 - - 0.0
393
1 - - 0.0
449
1 - - 0.0
469
1 - - 0.0
387
1 - - 0.0
461
1 - - 0.0
425
1 - - 0.0
424
1 - - 0.0
395
1 - - 0.0
434
1 - - 0.0
442
1 - - 0.0
429
1 - - 0.0
409
1 - - 0.0
471
1 - - 0.0
465
1 - - 0.0
412
1 - - 0.0
479
1 - - 0.0
433
1 - - 0.0
440
1 - - 0.0
423
1 - - 0.0
467
1 - - 0.0
481
1 - - 0.0
474
1 - - 0.0
422
1 - - 0.0
402
1 - - 0.0
484
1 - - 0.0
464
1 - - 0.0
472
1 - - 0.0
439
1 - - 0.0
411
1 - - 0.0
478
1 - - 0.0
398
1 - - 0.0
407
1 - - 0.0
397
1 - - 0.0
459
1 - - 0.0
435
1 - - 0.0
401
1 - - 0.0
404
1 - - 0.0
420
1 - - 0.0
448
1 - - 0.0
455
1 - - 0.0
457
Hsp40
1 - - 0.0
419
1 - - 0.0
406
1 - - 0.0
396
1 - - 0.0
482
1 - - 0.0
470
Prokaryotic heat shock protein
1 - - 0.0
403
1 - - 0.0
466
1 - - 0.0
421
1 - - 0.0
450
1 - - 0.0
473
1 - - 0.0
390
1 - - 0.0
408
1 - - 0.0