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CATH Superfamily 1.10.246.200

WPP domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
WPP domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: WPP domain

Structural domains comprising this superfamily share the structure of the WPP domain, thought to be exclusively found in plants. WPP stands for a tryptophan-proline-proline motif that is highly conserved in the domain PMID:11115866. This domains directs RanGAP (Ran GTPase-activating protein) to the nuclear envelope PMID:11752475. Non-RanGAP nuclear envelope proteins have also been shown to encode WPP domains, such as MFP1 attachment factor 1 (MAF1) PMID:11115866, WPP1 and WPP2 PMID:15548735.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.

PFAM:PF13943 (WPP)

GO Diversity

Unique GO annotations
16 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
124 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Function
Unique EC:
Unique GO: 16
Taxonomy
Unique Species: 124