The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
5442
14442
EC
- - 58.9
32677
7315
EC
- - 87.9
32897
5030
EC
- - 75.0
2019
5011
EC
- - 70.1
32069
3622
EC
- - 83.2
32870
3564
EC
- - 92.8
32785
2820
EC
- - 90.5
32882
1955 - - 96.9
1412
Phosphorylase kinase, delta
1894
EC
- - 72.0
4326
1326
EC
- - 84.3
33022
1274
EC
- - 90.6
33121
1241 - - 86.2
32250
1221
EC
- - 85.5
407
1159 - - 84.9
33188
1082
EC
- - 94.0
4181
1066 - - 97.5
32080
1048
EC
- - 80.8
570
1031 - - 66.9
4988
1013
EC
- - 82.8
32884
945 - - 94.9
33122
810 - - 90.0
33456
777
EC
- - 94.2
32905
765 - - 84.9
32665
691
EC
- - 80.6
11876
665 - - 91.7
33093
654
EC
- - 81.1
32239
643
EC
- - 93.3
32889
617
EC
- - 94.4
32498
555 - - 90.9
31845
529 - - 88.9
14551
519 - - 96.1
32801
496
EC
- - 89.4
33135
491 - - 99.0
665
481 - - 86.4
32536
464 - - 94.5
32575
461 - - 94.5
32067
454 - - 87.7
12114
448
EC
- - 86.6
32468
431
EC
- - 95.3
32652
422 - - 75.6
32817
417
EC
- - 87.3
13331
380 - - 81.7
32060
375 - - 77.7
32671
360 - - 89.1
971
315 - - 89.5
15672
310
EC
- - 71.5
7045
302 - - 66.0
243
291 - - 86.8
14118
290
EC
- - 71.5
31913
285 - - 87.5
31996
263
EC
- - 98.9
7743
260 - - 94.4
33210
238
EC
- - 95.9
32347
237
EC
- - 76.9
32312
235 - - 71.8
32760
232
EC
- - 77.0
32059
228 - - 70.7
32344
226 - - 83.0
32587
226 - - 79.5
32541
220 - - 91.1
32578
219 - - 91.5
16751
219 - - 76.1
20953
217 - - 88.2
7227
212
EC
- - 88.9
4566
206
EC
- - 20.1
31928
203 - - 82.2
13256
200 - - 76.3
7335
193
EC
- - 89.0
32777
191
EC
- - 62.9
32105
187
EC
- - 79.9
33053
185 - - 94.4
33380
184 - - 70.3
8273
181 - - 93.8
10658
181 - - 74.2
32562
181 - - 78.6
9572
172 - - 59.4
32787
Skeletal
172 - - 48.0
32761
166
EC
- - 94.6
33402
165 - - 80.2
32634
164
EC
- - 85.2
15765
162 - - 54.9
13559
158 - - 86.8
16128
149
EC
- - 38.6
32915
144 - - 69.7
32264
143 - - 89.0
33071
137
EC
- - 85.5
1982
137 - - 11.6
21526
137 - - 47.4
32378
136 - - 67.4
6294
136
EC
- - 6.0
32669
135
EC
- - 80.2
32825
135
EC
- - 89.4
5082
134 - - 31.3
10747
134
EC
- - 86.3
6600
133
EC
- - 72.1
4015
132 - - 91.4
32351
130
EC
- - 61.7
3571
128
EC
- - 17.3
4549
128 - - 81.5
32032
128 - - 44.0
15954
123
EC
- - 38.1
17088
123
EC
- - 53.6
32373
118 - - 85.0
15872
116
EC
- - 50.4
8465
116 - - 35.9
32430
114 - - 71.0
24007
Predicted
112 - - 40.1
32619
112 - - 46.7
14657
108 - - 75.6
13064
108 - - 26.0
32515
107 - - 76.6
891
104 - - 60.8
15226
103 - - 62.8
2405
102 - - 47.7
32470
102 - - 60.0
32466
102
EC
- - 52.4
32879
102
EC
- - 84.4
15755
102
EC
- - 47.5
33075
100
EC
- - 80.4
32353
99
EC
- - 64.9
7470
97 - - 78.0
33311
97 - - 94.3
32477
96
EC
- - 37.1
33077
96 - - 92.4
32467
95 - - 45.0
32538
95 - - 65.4
32487
95 - - 15.7
12911
92 - - 77.3
32941
92
EC
- - 82.8
18327
92
EC
- - 60.8
32779
91 - - 41.9
32206
90 - - 80.2
32614
90 - - 77.5
32287
88 - - 56.8
11005
88 - - 89.2
9299
86
EC
- - 68.5
9788
84 - - 0.6
3340
84 - - 47.5
9952
83 - - 30.9
33074
80
EC
- - 70.7
16749
79 - - 4.2
18008
78 - - 76.1
16997
77 - - 49.0
12564
76 - - 85.0
10037
74
EC
- - 43.4
32744
73 - - 87.5
33439
73 - - 80.1
14249
71
EC
- - 30.1
32502
71 - - 63.9
32659
71
EC
- - 18.2
14819
67 - - 75.4
32539
66 - - 58.2
6741
66 - - 76.4
2856
62 - - 85.5
12808
62 - - 39.7
19213
61 - - 64.2
32390
61 - - 40.3
32617
59 - - 77.2
32463
57 - - 41.7
19430
57 - - 46.9
13360
56 - - 4.0
10737
55 - - 66.0
15586
55
EC
- - 56.9
33253
54 - - 47.8
33141
54 - - 86.2
6766
54 - - 83.2
32095
54 - - 62.7
17056
54 - - 0.0
27884
52 - - 14.6
16750
52 - - 59.5
32030
52 - - 51.9
32367
52
EC
- - 37.6
16224
51 - - 32.1
33313
50 - - 82.5
33145
49 - - 77.5
23073
48 - - 33.0
32399
48 - - 71.0
164
48 - - 7.0
1924
47
EC
- - 95.8
12441
47 - - 40.8
8448
43 - - 65.6
31925
42
EC
- - 43.0
32593
41 - - 24.4
22744
41
EC
- - 21.7
146
41 - - 71.4
15391
39
EC
- - 48.6
32756
39
EC
- - 76.8
14128
39 - - 90.0
17978
39 - - 18.5
32830
38 - - 98.3
32940
37 - - 74.3
14034
37 - - 43.7
32750
36 - - 68.0
33101
35 - - 59.3
32763
35 - - 81.0
33289
34
EC
- - 6.8
32584
33 - - 50.8
20391
33 - - 48.9
16481
33 - - 17.5
21071
33 - - 18.4
30475
32 - - 27.2
33131
29 - - 60.7
11786
27 - - 10.1
31919
27 - - 27.0
24874
26
EC
- - 56.9
32158
26 - - 59.3
32240
24
EC
- - 81.3
33382
24
EC
- - 88.3
13158
24 - - 14.1
380
23 - - 2.4
33056
22
EC
- - 49.4
5284
21
EC
- - 43.0
3512
21 - - 20.9
32200
21 - - 53.8
33332
20 - - 84.9
32293
20 - - 67.1
31970
20 - - 36.1
32945
20 - - 77.7
10815
19 - - 9.4
19874
19 - - 5.3
32699
18 - - 50.7
18909
18 - - 33.4
32197
18 - - 46.2
4178
18 - - 16.6
32346
17
EC
- - 25.0
32925
17 - - 68.8
23289
17 - - 40.3
22783
17 - - 17.4
14306
16 - - 64.2
5007
16 - - 8.6
11284
16 - - 28.8
9861
16 - - 30.8
14694
15
EC
- - 14.1
33068
15
EC
- - 80.6
20053
15 - - 34.6
19506
14 - - 0.0
9676
14 - - 16.9
32313
14 - - 13.1
32395
14 - - 8.2
32702
14 - - 50.8
33383
13 - - 81.9
32628
13 - - 7.1
16516
13 - - 41.1
32771
13 - - 0.8
32986
13 - - 56.6
6576
13 - - 39.9
29224
11
EC
- - 22.8
32856
11
EC
- - 77.0
15573
11 - - 20.6
32457
11 - - 90.8
26740
10 - - 18.4
1281
10 - - 29.5
32386
10 - - 40.6
32881
9 - - 69.1
8941
9 - - 31.7
2522
9 - - 60.7
31868
9
EC
- - 32.2
12069
9 - - 7.3
656
9 - - 12.8
33262
P
9 - - 86.7
16016
9
EC
- - 11.1
32737
8 - - 52.3
16741
8
EC
- - 13.8
32610
8 - - 0.7
32120
Endoplasmic reticulum
8 - - 12.6
20678
8 - - 0.0
8274
7 - - 28.0
19218
7
EC
- - 11.3
32991
7 - - 68.6
32108
7 - - 22.2
20991
7 - - 14.9
6112
7 - - 65.3
20028
7 - - 4.4
33242
7 - - 61.0
7446
7 - - 32.5
8492
6 - - 39.6
32127
6 - - 17.4
13715
6 - - 20.0
16344
6 - - 31.3
8916
6 - - 20.3
15218
6 - - 9.9
33004
6
EC
- - 25.9
33267
6 - - 79.1
7385
6 - - 16.5
21599
6 - - 3.3
32667
6 - - 45.8
27175
5
EC
- - 0.0
1628
5 - - 1.4
6797
5 - - 16.6
32365
5 - - 5.9
15473
5
EC
- - 6.7
32803
5 - - 0.0
14695
5 - - 7.8
19216
5
EC
- - 1.6
1031
4 - - 10.5
19888
4
EC
- - 5.9
32055
4 - - 13.4
13200
4 - - 0.0
15728
4 - - 0.0
17645
4 - - 21.2
16372
4
EC
- - 21.6
3195
4 - - 7.5
32646
4 - - 25.2
32828
3 - - 32.8
11084
3 - - 21.0
18656
3
EC
- - 0.0
7216
3 - -
31966
3
EC
- - 4.0
15194
3
EC
- - 14.1
11117
3 - - 0.0
33527
3 - - 0.0
22882
3 - - 9.5
1929
3 - - 10.6
8066
3
EC
- - 12.7
31852
3 - - 8.2
23016
3 - - 25.9
23128
2
EC
- - 0.0
653
2 - - 4.2
3931
2 - - 2.9
23171
2
EC
- - 0.0
19807
2 - -
17075
2 - - 0.0
20952
2 - - 3.7
8462
2 - - 1.5
3550
2 - - 4.3
32978
2 - - 32.1
15725
AFU_orthologue AFUA_3G13970
2
EC
- - 0.0
20423
2 - - 0.0
776
2 - - 3.6
20085
2 - - 1.3
32721
2 - -
4179
2
EC
- - 7.9
21762
2 - - 0.0
13079
2 - - 3.2
20086
2 - - 0.0
32570
2 - - 40.9
22529
2
EC
- - 0.0
31862
2 - - 11.8
33524
2 - - 47.1
33106
2 - - 14.1
32486
2 - -
20234
2 - - 0.0
20087
2 - - 0.0
10416
1 - - 0.0
23519
1 - - 0.0
32821
1 - -
21215
1 - - 0.0
21558
1 - - 0.0
20089
1 - - 0.0
32522
1
EC
- - 0.0
2848
1 - - 0.0
32056
1 - -
18301
1 - - 0.0
32010
1 - -
32931
1 - - 0.0
22168
1 - - 0.0
9310
1 - - 0.0
11197
1 - - 0.0
16080
1 - - 0.0
32318
1 - - 0.0
8756
1 - - 0.0
8522
1 - - 0.0
24009
1 - - 0.0
32727
1 - - 0.0
32627
1 - - 0.0
33459
1 - - 0.0
33228
1 - - 0.0
11139
1
EC
- - 0.0
33040
1
EC
- - 0.0
32795
1 - - 0.0
33429
1 - - 0.0
30038
1 - - 0.0
32123
1 - -
3352
1 - - 0.0
12721
1 - -
20658
1 - - 0.0
23305
1 - - 0.0
21243
1 - - 0.0
11513
1 - - 0.0
2125
1 - - 0.0
16551
1 - - 0.0
31177
1 - - 0.0
655
1 - - 0.0
33308
1 - - 0.0
27761
1 - - 0.0
11246
1 - - 0.0